What Is Schistosomiasis?

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Konsep:

Sasaran: traveler
Konten:
- Definisi: pt
- Epidemiologi: pt, insert picture
- Patofisiologi
- Faktor risiko: pt
- Life cycle of S: morfologi: pt
- Gejala klinis: pt, insert picture
- Pencegahan: pt
- Tagline: RAGIEL
Materials:
- Backsound
- Narrator
- Some pictures
Definisi:

What is schistosomiasis?
Narrator: Schistosomiasis, also known as snail fever, is a disease caused by
parasitic worms. Banyak jenis Schistosoma. Infection with Schistosoma
mansoni, S. haematobium, and S. japonicum causes illness in humans; less
commonly, S. mekongi and S. intercalatum can cause disease.
Pt:
-

also known as snail fever


caused by parasitic worms
Schistosoma mansoni, S. haematobium, and S. japonicum causes
illness in humans

Source:

Epidemiologi:
Distibution:

sources: journal

At least 249 million people required treatment for


schistosomiasis in 2013

While the actual number of people treated in 2012 was only 42.1 million.

Schistosomiasis is prevalent in tropical and subtropical areas


Schistosomiasis is especially prevalent in poor communities with unsafe
safe drinking-water sources and inadequate sanitation.
It is estimated that at least 90% of those requiring treatment for
schistosomiasis live in Africa.

Source:

Patofisiologi:
Source:

Infection occurs from exposure to infested freshwater

People can become infected during routine agricultural, domestic,


occupational and recreational activities which expose them to infested
freshwater sources.

Larval forms of schistosomiasis are released by snails

People become infected when larval forms of the parasite released by


freshwater snails penetrate the skin during contact with infested water

Life Cycle

Narrator: Freshwater becomes contaminated by Schistosoma eggs


when infected people urinate or defecate in the water. The eggs
hatch, and if certain types of freshwater snails are present in the
water, the parasites develop and multiply inside the snails. The
parasite leaves the snail and enters the water where it can survive
for about 48 hours. Schistosoma parasites can penetrate the skin of
persons who are wading, swimming, bathing, or washing in
contaminated water. Within several weeks, parasite mature into
adult worms, residing in the blood vessels of the body where the
females produce eggs. Some of the eggs travel to the bladder or
intestine and are passed into the urine or stool.

Eggs are eliminated with feces or urine


. Under optimal conditions
the eggs hatch and release miracidia
, which swim and penetrate
specific snail intermediate hosts
. The stages in the snail include 2
generations of sporocysts
and the production of cercariae
.
Upon release from the snail, the infective cercariae swim, penetrate
the skin of the human host
, and shed their forked tail, becoming
schistosomulae
. The schistosomulae migrate through several
tissues and stages to their residence in the veins ( ,
). Adult
worms in humans reside in the mesenteric venules in various
locations, which at times seem to be specific for each species
.
For instance, S. japonicum is more frequently found in the superior
mesenteric veins draining the small intestine
, and S. mansoni
occurs more often in the superior mesenteric veins draining the
large intestine
. However, both species can occupy either location,
and they are capable of moving between sites, so it is not possible
to state unequivocally that one species only occurs in one location.
S. haematobium most often occurs in the venous plexus of bladder
, but it can also be found in the rectal venules. The females (size
7 to 20 mm; males slightly smaller) deposit eggs in the small
venules of the portal and perivesical systems. The eggs are moved
progressively toward the lumen of the intestine (S. mansoni and S.

japonicum) and of the bladder and ureters (S. haematobium), and


are eliminated with feces or urine, respectively
. Pathology of S.
mansoni and S. japonicum schistosomiasis includes: Katayama
fever, hepatic perisinusoidal egg granulomas, Symmers pipe stem
periportal fibrosis, portal hypertension, and occasional embolic egg
granulomas in brain or spinal cord. Pathology of S. haematobium
schistosomiasis includes: hematuria, scarring, calcification,
squamous cell carcinoma, and occasional embolic egg granulomas in
brain or spinal cord.

What are the signs and symptoms of schistosomiasis?


Within days after becoming infected, you may develop a rash or
itchy skin. Fever, chills, cough, and muscle aches can begin within
1-2 months of infection. Most people have no symptoms at this
early phase of infection.
When adult worms are present, the eggs that are produced usually
travel to the intestine, liver or bladder, causing inflammation or
scarring. Children who are repeatedly infected can develop anemia,
malnutrition, and learning difficulties. After years of infection, the
parasite can also damage the liver, intestine, lungs, and bladder.
Rarely, eggs are found in the brain or spinal cord and can cause
seizures, paralysis, or spinal cord inflammation.

Symptoms of schistosomiasis are caused by the body's reaction to


the eggs produced by worms, not by the worms themselves.
Faktor resiko :
Anak anak

traveler

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