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    2012 SLICC SLE Criteria - RheumTutor

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    The document outlines the 2012 Systemic Lupus International Collaborating Clinics (SLICC) criteria for systemic lupus erythematosus (SLE). It lists 11 clinical and 6 immunologic criteria that can be used to classify SLE. The criteria are cumulative and do not need to be present concurrently. Some examples of clinical criteria include malar rash, discoid rash, oral ulcers, arthritis, serositis, and renal disease. Immunologic criteria include positive tests for antinuclear antibodies, anti-double stranded DNA, anti-Smith antibodies, and low complement levels. A patient must meet at least 4 criteria, either clinical or immunologic, to be classified as having SLE.

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    2012 SLICC SLE Criteria - RheumTutor

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    gkrgag
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    The document outlines the 2012 Systemic Lupus International Collaborating Clinics (SLICC) criteria for systemic lupus erythematosus (SLE). It lists 11 clinical and 6 immunologic criteria that can be used to classify SLE. The criteria are cumulative and do not need to be present concurrently. Some examples of clinical criteria include malar rash, discoid rash, oral ulcers, arthritis, serositis, and renal disease. Immunologic criteria include positive tests for antinuclear antibodies, anti-double stranded DNA, anti-Smith antibodies, and low complement levels. A patient must meet at least 4 criteria, either clinical or immunologic, to be classified as having SLE.

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    2012 SLICC SLE Criteria _ RheumTutor

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    The document outlines the 2012 Systemic Lupus International Collaborating Clinics (SLICC) criteria for systemic lupus erythematosus (SLE). It lists 11 clinical and 6 immunologic criteria that can be used to classify SLE. The criteria are cumulative and do not need to be present concurrently. Some examples of clinical criteria include malar rash, discoid rash, oral ulcers, arthritis, serositis, and renal disease. Immunologic criteria include positive tests for antinuclear antibodies, anti-double stranded DNA, anti-Smith antibodies, and low complement levels. A patient must meet at least 4 criteria, either clinical or immunologic, to be classified as having SLE.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    161 views3 pages

    2012 SLICC SLE Criteria - RheumTutor

    Uploaded by

    gkrgag
    The document outlines the 2012 Systemic Lupus International Collaborating Clinics (SLICC) criteria for systemic lupus erythematosus (SLE). It lists 11 clinical and 6 immunologic criteria that can be used to classify SLE. The criteria are cumulative and do not need to be present concurrently. Some examples of clinical criteria include malar rash, discoid rash, oral ulcers, arthritis, serositis, and renal disease. Immunologic criteria include positive tests for antinuclear antibodies, anti-double stranded DNA, anti-Smith antibodies, and low complement levels. A patient must meet at least 4 criteria, either clinical or immunologic, to be classified as having SLE.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
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    7/10/2014

    2012 SLICC SLE Criteria | RheumTutor.com

    RheumTutor.com
    Providing quality
    education in
    rheumatology

    2012 SLICC SLE Criteria


    Criteria are cumulative and need not be present concurrently. See notes below.

    CLINICAL CRITERIA
    (1) Acute Cutaneous Lupus OR Subacute Cutaneous Lupus
    Acute cutaneous lupus: lupus malar rash (do not count if malar discoid), bullous
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    lupus, toxic epidermal necrolysis variant of SLE, maculopapular lupus rash,


    photosensitive lupus rash (in the absence of dermatomyositis)
    Subacute cutaneous lupus: nonindurated psoriaform and/or annular polycyclic
    lesions that resolve without scarring, although occasionally with postinflammatory
    dyspigmentation or telangiectasias)
    (2) Chronic Cutaneous Lupus
    Classic discoid rash localized (above the neck) or generalized (above and below the
    neck), hypertrophic (verrucous) lupus, lupus panniculitis (profundus), mucosal lupus,
    lupus erythematosus tumidus, chillblains lupus, discoid lupus/lichen planus overlap
    (3) Oral Ulcers OR Nasal Ulcers
    Oral: palate, buccal, tongue
    Nasal ulcers
    In the absence of other causes, such as vasculitis, Behcets disease, infection
    (herpesvirus), inflammatory bowel disease, reactive arthritis, and acidic foods
    (4) Nonscarring alopecia
    Diffuse thinning or hair fragility with visible broken hairs, in the absence of other
    causes such as alopecia areata, drugs, iron deficiency, and androgenic alopecia
    (5) Synovitis involving 2 or more joints
    Characterized by swelling or effusion
    OR tenderness in 2 or more joints and at least 30 minutes of morning stiffness
    (6) Serositis
    Typical pleurisy for more than 1 day OR pleural effusions OR pleural rub
    Typical pericardial pain (pain with recumbency improved by sitting forward) for more
    than 1 day OR pericardial effusion OR pericardial rub OR pericarditis by
    electrocardiography
    In the absence of other causes, such as infection, uremia, and Dresslers pericarditis
    (7) Renal
    Urine proteinto-creatinine ratio (or 24-hour urine protein) representing 500 mg
    protein/24 hours OR red blood cell casts
    (8) Neurologic
    Seizures, psychosis, mononeuritis multiplex(in the absence of other known causes
    such as primary vasculitis), myelitis, peripheral or cranial neuropathy (in the absence
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    of other known causes such as primary vasculitis, infection, and diabetes mellitus),
    acute confusional state (in the absence of other causes, including toxic/metabolic,
    uremia, drugs)
    (9) Hemolytic anemia
    (10) Leukopenia (<4000/mm3) OR Lymphopenia (<1000/mm3)
    Leucopenia at least once: In the absence of other known causes such as Feltys
    syndrome, drugs, and portal hypertension.
    Lymphopenia at least once: in the absence of other known causes such as
    corticosteroids, drugs, and infection
    (11) Thrombocytopenia (<100,000/mm3)
    At least once in the absence of other known causes such as drugs, portal
    hypertension, and thrombotic thrombocytopenic purpura
    IMMUNOLOGIC CRITERIA
    (1) ANA level above laboratory reference range
    (2) Anti-dsDNA antibody level above laboratory reference range (or 2-fold the reference
    range if tested by ELISA)
    (3) Anti-Sm: presence of antibody to Sm nuclear antigen
    (4) Antiphospholipid antibody positivity, as determined by
    Positive test for lupus anticoagulant
    False-positive test result for rapid plasma reagin
    Medium- or high-titer anticardiolipin antibody level (IgA, IgG, or IgM)
    Positive test result for anti2-glycoprotein I (IgA, IgG, or IgM)
    (5) Low complement (C3, C4, or CH50)
    (6) Direct Coombs test (in the absence of hemolytic anemia)

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