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    20-Inorganic Pharmaceutical Chemistry

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    work. The laboratory work takes place 3 hours once per week in the laboratories of the School of Pharmacy.

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    20-Inorganic Pharmaceutical Chemistry

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    thucinor
    294 views4 pages
    work. The laboratory work takes place 3 hours once per week in the laboratories of the School of Pharmacy.

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    Inorganic pharmaceticual

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    work. The laboratory work takes place 3 hours once per week in the laboratories of the School of Pharmacy.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    294 views4 pages

    20-Inorganic Pharmaceutical Chemistry

    Uploaded by

    thucinor
    work. The laboratory work takes place 3 hours once per week in the laboratories of the School of Pharmacy.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 4

    20-INORGANIC PHARMACEUTICAL CHEMISTRY

    Aims of the course: Understanding by the students of inorganic drug, including


    chemical properties and biological role as well as of elements (metals and metalloids)
    involved in its structure and synthesis. Aims comprise knowledge and skill (capacity)
    of synthesis, qualitative control, characterization, quantitative control of
    pharmaceutical preparations which contain inorganic drugs, their mechanism of action
    at the molecular level as well as their use and side effects.

    Scills: Familiarity with basic knowledge: a) biological activity of metals-metalloids b)


    biological activity of inorganic compounds of pharmaceutical interest, c) their
    interaction
    with
    biological
    targets
    and
    d)
    their
    characterization

    qualitative/quantitative control.
    Teaching methods:
    Lectures and Laboratory work.
    Contents of the course:
    Inspection of elements in the groups of periodic table in respect with ChemistryPharmacological/Toxicological activity, biological activity of metals-metalloids,
    inorganic compounds of pharmaceutical interest: synthesis/origin , quality/quantity
    control, properties, uses, side effects and their chemical explanation.
    Group
    Lithium. Lithium carbonate. Natrium (sodium), natrium carbonicum
    and bicarbonicum, natrium sulfuricum, natrium thiosulfatum, natrium
    citricum,natrium tetraboracium, natrium fluoratum, natrium chloratum,
    natrium phosphoricum bibasicum andbiphosphoricum.
    Potassium. Kalium iodatum, kalium permanganicum,potassium
    chloride.
    Group
    . Magnesium, magnesium oxydatum, magnesium
    carbonicum leve, magnesium sulfuricum, magnesium steaticum and
    trisylicicum, magnesium hydroxidatum , magma magnesiamagnesium
    chloratum.
    Calcium. Calcium phosphoricum dibasicum, calcium phosphate,calcium
    chloride , calcium glyconicum, calcium sulfuricum, calcium
    hydroxidatum, calcium hydroxidatum solution, CalcciumPharmacology.
    Barium. Barium sulfuricum .
    Group
    Borium. Acidum boricum.
    Aluminium. Aluminium hydroxidatum, colloidale, aluminium
    hydroxidatum gelatum siccum, alumen.
    Group V
    Carboneum, carboneum activate.
    Silicium. Bentonitum, Kaolinum leve- Bolus-alba laevigata, talcum
    purificatum.
    Pliumbum.
    Group V
    Nitrogenum. Oxydum nitrosum, ammonia concentrate,ammonium
    hydricum solutum, ammonium carbonicum,ammonium chloratum.
    Arsenicum.Acidum arsenicum. Toxicity of arsenicums compounds and
    their antidotes.
    Stibium, Stibio-kalium tartaricum.
    Bismuthum.
    Group V

    Oxygenium. Aqua destilata.Hydrogenium peroxidatum.


    Sulfur. Sulfur praecipitatum..
    Group V
    Halogens.Acidum hydrochloricum, cxalcaria chlorata (calcium
    hypochlorosum.
    Iodum. Tinctura iodi.
    Magganium as trace element.
    Sub-groip
    Cuprum. Cuprum sulfuricum. Role of cuprum in organism. Cuprum
    sulfuricum.
    Argentum. Argentum nitricum.Argentum compounds .
    Sub-group
    Zincum.Zincum oxidatum. Zincum as trace element. Consequences of
    its deficient in organism.. Interaction of zincum with vitamines..
    Hydrargirum. Hydrargyrum oxidatum flavum.Hydrargyrum
    bichloratum.. Hydrargirum cyanicum.
    Group V
    Ferrum. Ferrum as trace element. Ferrum glyconicum. Ferrum
    sulfuricum.
    Also:
    Tungsten, Thallium, Cadmium, Cobalt, Selenium, Vanadium, Nickel,
    Platinum and compounds in pharmaceutical use as drugs.
    Proposed Literature:
    1. Remingtons:Pharmaceutical Sciences 14 Ed.Mac.Publishing Co.,
    Easton, 1970.
    2. Rogers Inorganic Pharmaceutical Chemistry, 8th ed., by T.O.Soine
    and C.O.Wilson, Lea and Felinger, Filadelfia, 1967.
    3. Bio-inorganic Chemistry R.W.Hay, editor llis Horwood (in Greek
    language by . - & . ). Editor Papazisis, 1992
    4. Bioinorganic Chemistry: Inorganic Elements in the Chemistry and
    Life. An Introduction and Guide. W. Kaim & B. Schwderski. Editor
    Wiley, 1994
    5. National Formulary, National Drug Organization 2007

    Educational activities:
    Lectures and laboratory work.
    Evaluation process and methods: Advance written exams (A), exams in the end of
    semester (B).
    Examination is based on some questions which should be answered according to the
    obtained knowledge during semester as well as to the ability to combine knowledge
    with information and the critical thought of the students.
    Exams in the end of semester take place on date and hours as well as in auditoriums
    announced by the Department.
    Duration of exams is 3 h.
    Marks are rotatable.
    ) Advance examination
    The right to participate in this examination is given to students of the 3d semester
    who have attended the lectures (3 among 6 lectures).
    There are two examinations, one in the middle of the course and another to the end.
    Only students who have succeeded (mark 5 or higher) in the first examination can

    participate in the second. Students succeeded in this examination are relieved from
    the examination in the end of semester and the total mark is an average of two
    examinations.
    During laboratory practice students present the composition of their results. At the
    end of laboratory practice students have a written examination. Success in laboratory
    practice (average of notebook and test should be 5 at least) is obliged for the
    participation in exams in the end of semester. The laboratory practice mark
    represents the 20% of the final mark.
    Use of IC / Electronic distribution of the lectures:
    Tutors:
    1) A. Geronikaki
    Lectures are presented as Powerpoint.
    2) Dimitra Hadjipavlou-Litina, professor
    Lectures, notes, statements etc are presented in the corresponding place of the
    website of the School of Pharmacy.
    Teaching:
    ) Lectures. The lectures take place 1 hour twice per week uditorium D12, in the
    building of the School of Natural Sciences.

    Lecture
    1
    2-4
    5
    6
    7
    8
    9

    10
    11
    12
    13
    14

    15
    16
    17
    18
    19
    20-21

    Title
    Quality and quantity control
    Group .Introduction. Lithium, lithium
    carbonicum. Natrium and its compounds
    Compounds of sodium and potassium
    Group .Introduction. Magnesium and
    its compounds
    Magnesium and its compounds. Calcium
    Compounds of calcium
    Compounds of calcium,its
    pharmacology. Barium. Barium
    sulfuricum.
    Group . Borium and its compounds
    Group . Aluminum and its compounds
    Aluminum and its compounds
    Group IV.Carboneum.Carboneum
    activate. Silicium
    Group IV.Bentonite, Kaolin and talcum.
    Pliumbum, its absorption, toxicity and
    therapy.
    Group V.Nutrogenum and its
    compounds
    Bismuthium. Group V. xygenium
    Aqua destilata, hydrogenium
    peroxidatum
    Sulfur. Group V. Halogens, fluoride as
    trace element , hydrochloric acid, ,
    calcaria chlorata
    odine . Manganium
    Arsenic-Antinonium

    Tutor
    A. Geronikaki
    A. Geronikaki
    A. Geronikaki
    A. Geronikaki
    A. Geronikaki
    A. Geronikaki
    A. Geronikaki

    A.
    A.
    A.
    A.

    Geronikaki
    Geronikaki
    Geronikaki
    Geronikaki

    A. Geronikaki

    A. Geronikaki
    A. Geronikaki
    A. Geronikaki
    A. Geronikaki
    A. Geronikaki
    D.Hadjipavlou-

    22

    Tungsten, Thallium, Cadmium, Cobalt

    23-24

    Selenium,Vanadium,Nickel,Platinum

    25-26

    Copper, Mercury, Zinc

    Laboratory
    1-3

    Title
    Preparation of boric acid and calcium
    phosphoricum bibasicum.
    Praparation of original solutions

    4-5

    Quantitative determination of borax


    and boric acid

    6-8

    Quantitative determination of tincture


    iodine (I2 + KI)

    Quantitative determination of ferrum


    sulfuricum and potassium
    permanganicum
    Quantitative determination of cuprum
    sulfuricum

    10

    11

    Quantitative determination of
    magnesium sulfuricum

    12

    Quantitative determination of KMnO4


    by chromatometric method

    13

    Quantitative determination of sodium


    sulfuricum

    Litina
    D.HadjipavlouLitina
    D.HadjipavlouLitina
    D.HadjipavlouLitina
    Tutor
    Geronikaki,
    HadjipavlouLitina, Gavalas
    Geronikaki,
    HadjipavlouLitina, Gavalas
    Geronikaki,
    HadjipavlouLitina, Gavalas
    Geronikaki,
    HadjipavlouLitina, Gavalas
    Geronikaki,
    HadjipavlouLitina, Gavalas
    Geronikaki,
    HadjipavlouLitina, Gavalas
    Geronikaki,
    HadjipavlouLitina, Gavalas
    Geronikaki,
    HadjipavlouLitina, Gavalas

    )
    Laborator
    y

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