Sagittal Imbalance of Spine
Sagittal Imbalance of Spine
Sagittal Imbalance of Spine
Sagittal Imbalance
Peter D. Angevine, MD, MPHa,*, Keith H. Bridwell, MDb
a
Sagittal imbalance is a general term encompassing spinal deformities that include a signicant
component of forward postural instability. Conceptually, sagittal imbalance results from a loss
of harmony between the normal regional contours
of the spine. Bernhardt and Bridwell [1] determined that a well-balanced spine generally has between 10 and 30 more lumbar lordosis than
thoracic kyphosis. A relative loss of lumbar lordosis, increase in thoracic kyphosis, or combination
of the two may result in an anterior progression of
the proximal spine relative to the distal spine and
pelvis resulting in sagittal imbalance. Underlying
causes may include ankylosing spondylitis, spinal
arthrodesis in suboptimal alignment, pseudarthrosis, post-traumatic kyphosis, or degenerative disk
disease [25].
Sagittal imbalance may be segmental (type 1)
or global (type 2). Segmental sagittal imbalance
refers to a regional relative kyphosis (loss of
normal lordosis, frank kyphosis of normally
lordotic segment, or hyperkyphosis) with preserved C2 or C7 plumb line alignment (centered
over L5-S1 disk). To maintain overall normal
sagittal balance in the setting of regional relative
kyphosis, a distal hyperlordosis is generally present. Global sagittal imbalance is a deformity that
results in positive overall sagittal balance (C2 or
C7 plumb line O5 cm ventral to L5-S1 disk) [3].
Patients with sagittal imbalance may present
with complaints referable to the segmental or
* Corresponding author.
E-mail address: [email protected]
(P.D. Angevine).
1042-3680/06/$ - see front matter 2006 Elsevier Inc. All rights reserved.
doi:10.1016/j.nec.2006.04.005
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Deformity evaluation
Evaluation of the spinal deformity begins with
the clinical examination. The surgeon evaluates the
overall clinical sagittal and coronal balance and
associated factors, such as the ability of the patient
to maintain forward gaze while standing and
walking. Because a patient may compensate for
the spinal deformity with hip and knee exion, the
surgeon must account for the conguration of these
joints when evaluating overall balance (Fig. 1). The
exibility of the deformity also is evaluated. The patient is asked to lie supine and prone to determine
the amount of correction obtained with these postural changes. In some cases, the patient might
need to remain supine for a time to allow relaxation
and spontaneous correction.
The most important radiographic studies in
developing the surgical plan are the upright and
supine anteroposterior and lateral radiographs of
the entire spine. The supine and upright views are
compared carefully. Assessing regional and global
sagittal balance with appropriate Cobb angles and
plumb lines using the same landmarks on each
radiograph may reveal signicant exibility in an
otherwise formidable deformity. In some patients,
Fig. 1. (A) Patients may compensate for xed spinal deformities with knee and hip exion. (B) Full knee extension
reveals the extent of the positive global sagittal balance.
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Fig. 2. A 56-year-old woman with a history of spinal fracture treated with noninstrumented arthrodesis approximately
30 years before presentation. Chief complaints included back pain, leg pain, and postural changes with increasing forward and leftward tilt. Clinical examination was signicant for positive sagittal balance (A) and left-sided (negative) coronal imbalance (B). Anteroposterior (C) and lateral (D) upright radiographs show xed coronal and sagittal deformity.
The patient underwent an asymmetric L3 PSO with T8 to pelvis-instrumented fusion. Postoperative anteroposterior (E)
and lateral (F) upright radiographs and clinical photographs (G) show improved coronal and sagittal balance.
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Fig. 3. Algorithm for osteotomy type based on the character of the sagittal deformity. PSO, pedicle subtraction osteotomy; VCR, vertebral column resection.
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superior facet. Thoracic facetectomies are performed with a sharp 1/4- or 1/2-inch osteotome. A
sagittal cut is made at the medial aspect of the
inferior facet extending 5 mm or less proximally.
An axial cut is made with care not to use excessive
force, which risks facet fracture and a potentially
devastating neurologic injury. The underlying
superior facet protects against entry into the
spinal canal with the osteotome. Lumbar facetectomies are performed most easily and rapidly with
a Leksell rongeur oriented parallel to the articular
surfaces.
Obtaining xation
Correction of a signicant sagittal plane deformity requires the application and maintenance
of signicant forces to the spine; this mandates
multiple secure points of xation through which
corrective forces can be transmitted. Options for
segmental spinal instrumentation for deformity
correction include hooks (pedicle, laminar, and
transverse process) and pedicle screws [3]. Although hooks have been used in the thoracic spine
for a longer time and are more familiar to many surgeons, pedicle screws oer advantages that hooks
do not. As with any complex spinal instrumentation technique, the safe, appropriate use of hooks
or pedicle screws requires thorough training.
Closure of osteotomies requires strong xation. Although there are no iron-clad rules, fewer
than four points of xation proximal and distal to
an osteotomy may not be adequate to close and
hold an osteotomy without loosening of the
implant-bone interface [14].
Osteotomies
In cases of rigid kyphoses, partial facetectomies
may not loosen the deformity suciently to allow
adequate correction and restore normal sagittal
balance. Osteotomies provide further exibility to
the spine and, in the case of pedicle subtraction
osteotomies, allow correction in the setting of
circumferential fusion. These procedures must be
performed with meticulous attention to detail to
minimize the risk of neurologic injury.
Smith-Petersen osteotomy
The SPO (opening wedge or chevron osteotomy) allows the surgeon to shorten the posterior
column about an axis of rotation in the middle
column. The standard SPO involves removing the
ligamentum avum and the superior and inferior
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results in a shorter spinal canal. Greater correction can be obtained at a single level with a PSO
than with an SPO. An asymmetric PSO may be
used to correct sagittal imbalance combined with
a coronal deformity. SPOs may result in an
increase in coronal deformity particularly if signicant rotation is present [15].
The PSO technique has been described elsewhere, and a detailed description of the procedure
is beyond the scope of this article [11,12]. A few pitfalls in these technically demanding procedures can
be avoided. The posterior elements are completely
removed, and the pedicles are isolated. All removed
bone is saved for use as bone graft. Maintaining the
pedicle walls intact, particularly on the medial and
inferior aspects, facilitates bony removal from the
vertebral body by protecting the lateral dura and
the nerve root (Fig. 6). Bleeding can be brisk from
the vertebral body. Using hemostatic agents and alternating between sides can help to minimize blood
loss. After the cancellous bone has been removed
from the vertebral body, the dorsal cortex is pushed
into the defect with a down-going curette or Woodson elevator. The lateral cortical wall is the last portion of bone to be removed (Fig. 7). The surgeon
should not disarticulate the spine completely, but
should leave a ventral hinge of cortical bone.
This hinge helps to prevent a coronal shift in the
alignment, which, once it has occurred, can be
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Postoperative
Perioperative
The postoperative care of the patient begins in
the operating room. Procedures to correct sagittal
imbalance are often long and involve signicant
blood loss and large volumes of intravenous uid
and blood and blood products. The patient may
have signicant facial and laryngeal swelling. In
these circumstances, it may be advisable for patient
safety and comfort to keep the patient intubated
overnight to allow diuresis before extubation.
Whether the patient is extubated in the operating room or not, he or she should be awakened
suciently to perform a comprehensive neurologic examination. Particularly after the closure of
a lumbar PSO, individual myotome function
should be carefully examined bilaterally. Any
new decit should be investigated expeditiously
and treated appropriately, which may include
obtaining additional radiographic studies,
Fig. 9. Patient who underwent a previous lumbarinstrumented fusion. (A) Global (type II) sagittal imbalance developed as a result of a combination of
proximal and distal adjacent segment degeneration. (B)
Circumferential surgery consisting of extension of the
posterior instrumentation and fusion and an anterior
L5-S1 diskectomy and interbody fusion restored her
lumbar lordosis and overall sagittal balance.
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Fig. 10. Lateral postoperative radiograph shows proximal adjacent segment degeneration. Supine (A) and upright lateral (B) radiographs show the unstable/hypermobile spondylolisthesis at T9-10 proximal to instrumented construct.
arthrodesis should be examined on follow-up radiographs for signs of degeneration and progressive kyphosis. Attention should be paid to the
upper instrumented vertebra and the level immediately proximal to it to ensure that the regional
alignment is unchanged from previous radiographs (Fig. 10). A brief history and physical examination should be directed toward detecting
signs or symptoms of loss of correction or neural
compression in adjacent segments.
Summary
Sagittal imbalance may cause signicant pain
and functional limitations for patients. Successful
surgical treatment of sagittal plane deformities
can result in a signicant improvement in quality
of life for the patient. These complex procedures
may be associated with a relatively high rate of
complications. Careful planning, meticulous surgical technique, and vigilant postoperative followup may help to minimize the occurrence of
complications and optimize patient outcomes.
References
[1] Bernhardt M, Bridwell KH. Segmental analysis of
the sagittal plane alignment of the normal thoracic
and lumbar spines and thoracolumbar junction.
Spine 1989;14:71721.
[2] Gelb DE, Lenke LG, Bridwell KH, et al. An analysis
of sagittal spinal alignment in 100 asymptomatic
middle and older aged volunteers. Spine 1995;20:
13518.
[3] Booth KC, Bridwell KH, Lenke LG, et al. Complications and predictive factors for the successful
treatment of atback deformity (xed sagittal imbalance). Spine 1999;24:171220.
SAGITTAL IMBALANCE
[4] Lagrone MO, Bradford DS, Moe JH, et al. Treatment of symptomatic atback after spinal fusion.
J Bone Joint Surg Am 1988;70:56980.
[5] Bridwell KH, Lenke LG, Lewis SJ. Treatment of spinal stenosis and xed sagittal imbalance. Clin
Orthop 2001;384:3544.
[6] Glassman SD, Bridwell KH, Dimar JR, et al. The
impact of positive sagittal balance in adult spinal deformity. Spine 2005;30:20249.
[7] Berven SH, Deviren V, Smith JA, et al. Management
of xed sagittal plane deformity: outcome of combined anterior and posterior surgery. Spine 2003;
28:17106.
[8] Edwards CC 2nd, Bridwell KH, Patel A, et al. Thoracolumbar deformity arthrodesis to L5 in adults: the
fate of the L5S1 disc. Spine 2003;28:212231.
[9] Smith-Peterson MN, Larson CB, Aufranc OE.
Osteotomy of the spine for the correction of deformity in rheumatoid arthritis. J Bone Joint Surg Am
1945;45:111.
[10] Van Royen BJ, Slot GH. Closing-wedge posterior
osteotomy for ankylosing spondylitis: partial corpectomy and transpedicular xation in 32 cases.
J Bone Joint Surg Br 1995;77:11721.
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