Acepromazine

0.050.2mg/kg IV, 0.10.3mg/kg, IM, SC

(maximum 3 mg)
0.52.0mg/kg q68h PO
Acetazolamide
Diamox
510mg/kg q812h PO
Glaucoma: 48mg/kg q812h PO
Acetylcysteine
Mucomyst
Antidote: 140 mg/kg (loading dose) PO, IV, then
70mg/kg q4h for 5 doses
Eye: 2% solution topically q2h
Acetylsalicylic acid (aspirin)
Analgesic:
Dog: 1025mg/kg q812h PO
Anti-inflammatory:
Dog: 2040mg/kg q12h PO
Cat: 1020mg/kg q48h PO
Antiplatelet:
Dog: 510mg/kg q2448h PO
Cat: 80 mg q48h PO
ACTH
See Corticotropin gel (ACTH)
Actinomycin D
Cosmegen
0.7mg/m2 IV (consult anticancer protocol for
intervals)
Activated charcoal
See Charcoal, activated
Albendazole
Valbazen
Dog: 25mg/kg q12h PO for 2 days for giardia
Allopurinol
Zyloprim
10mg/kg q8h then reduce to 10mg/kg q24h
Aluminum carbonate gel
Basaljel
Phosphate binder: 1030mg/kg q8h PO (with
meals)
Aluminum hydroxide gel
Amphojel
Phosphate binder: 1030mg/kg q8h PO (with
meals)
Amikacin
Amiglyde-V

510mg/kg q8h IV, IM, SC; or 1520mg/kg q24h

IV, IM,
SC
Aminopentamide
Centrine
Dog: 0.010.03mg/kg q812h IM, SC, PO
Cat: 0.02mg/kg q812h IM, SC, PO
Aminophylline
Dog: 10mg/kg q8h PO, IM, IV
Cat: 6.6mg/kg q12h PO
5-aminosalicylic Acid
See Mesalamine; Osalazine sodium
Amiodarone
Cordarone
Dog: 1020mg/kg q12h PO
Amitraz
Mitaban
Make a 0.025% solution (1 vial of Mitaban/2
gallons of
water). Apply every 2 weeks until no viable mites
are
found (see Chap. 43).
Amitryptyline
Elavil
Dog: 12mg/kg q12h PO
Cat: 510mg/cat q1224h PO
Amlodipine
Norvasc
Cat: 0.6251.25mg/cat q24h PO
Dog: 0.10.2mg/kg q24h or divided q12h PO
Ammonium chloride
Dog: 100mg/kg q12h PO
Cat: 800mg/cat (approximately 1/4 tsp) mixed
with
food daily
Amoxicillin
Amoxi-tabs
Amoxi-drops
1122mg/kg q812h PO
Amoxicillin plus clavulanate
Clavamox
Dog: 12.525mg/kg q12h PO
Cat: 62.5mg/cat q12h PO
Amphotericin B deoxycholate
Fungizone

0.250.5 mg/kg q48h IV (slow infusion), 3 times

per week to
a cumulative dose of 812 mg/kg in dogs and 4
8mg/kg
in cats
Amphotericin B lipid complex
AmBisome, Amphocil, Abelcet
1.0mg/kg q48h IV, 3 times per week to a
cumulative dose of
12mg/kg (see Chap. 20)
Ampicillin
Omnipen
1020mg/kg q68h IV, IM, SC (ampicillin
sodium)
Principen
2040mg/kg q8h PO
Ampicillin trihydrate
Polyflex
6.5mg/kg q12h, IM, SC
Amprolium
Amprol
Corid
1.25 g of 20% amprolium powder added to daily
feed, or
30ml of 9.6% amprolium solution to 3.8 L of
drinking
water for 7 days
Amrinone lactate
Inocor
13mg/kg IV (loading dose) followed by 30
100mg/kg/min
IV infusion
Antacid drugs
See Aluminum hydroxide gel; Calcium
carbonate;
Magnesium hydroxide
Apomorphine hydrochloride
0.020.04mg/kg IV, IM; 0.1 mg/kg SC; or instill
0.25 mg in
conjunctiva of eye (dissolve 6-mg tablet in 12
ml of
saline)
Ascorbic acid (vitamin C)
Diet supplement or for copper toxicity 100
500mg/animal
qd
Acetaminophen toxicity 30 mg/kg q6h for seven
treatments,

PO, SC
L-Asparaginase
Elspar
10,00030,000IU/m2 IM, SC, or IP as needed
(pretreat with
antihistamines, steroids); see Chapter 26.
Aspirin
See Acetylsalicylic acid
Atenolol
Tenormin
Dog: 6.2525mg/dog q12h PO or 0.251.0mg/kg
q1224h PO
Cat: 6.2512.5mg/cat q24h PO
Atracurium besylate
Tracrium
0.2 mg/kg IV initially, then 0.15mg/kg q30min
(or IV
infusion at 38mg/kg/min)
Atropine
0.020.04mg/kg q68h IV, IM, SC
Organophosphate and carbamate toxicosis: 0.2
0.5mg/kg
(as needed)
Auranofin (triethylphosphine gold)
Ridaura
0.10.2mg/kg q12h PO
Aurothioglucose
Solganal
Dog <10kg: 1 mg/dog IM first week, 2mg/dog IM
second week, 1mg/kg/wk maintenance
Dog >10kg: 5 mg/dog IM first week, 10mg/dog
IM
second week, 1mg/kg/wk maintenance
Cat: 0.51 mg/cat IM every 7 days
Azathioprine
Imuran
Dog: 2mg/kg q24h PO initially, then 0.5
1.0mg/kg
q48h
Cat: 0.30.5 mg/kg PO, q2448h (q48h is
preferred)
Azithromycin
Zithromax
Dog: 10mg/kg q24h PO 5 days or 3.3mg/kg
q24h
PO 3 days
Cat: 5mg/kg q48h PO
AZT (azidothymidine)

See Zidovudine
Baclofern
Lioresal
Dogs: 12mg/kg q8h PO
BAL
See Dimercaprol
Benazepril
Lotensin
Dog: 0.5mg/kg q1224h PO
Betamethasone1
Celestone
Betasone
0.10.2mg/kg q1224h PO
Bethanechol chloride
Urecholine
Dog: 2.525.0mg/dog q8h PO
Cat: 2.55.0mg/cat q8h PO
Bicarbonate
See Sodium bicarbonate
Bisacodyl
Dulcolax
Dog: 520 mg qd PO
Cat: 5 mg qd PO
Bismuth subcarbonate
0.53.0 g q4h PO
Bismuth subsalicylate
Pepto-Bismol
13ml/kg/d (in divided doses) PO
Bleomycin sulfate
Blenoxane
10U/m2 IV or SC for 3 days, then 10U/m2
weekly
(maximum cumulative dose: 200U/m2)
Bromide
See Potassium bromide
Budesonide
Entocort
Dog: 13mg q24h PO
Cat: 1mg q24h PO
Bunamidine
Scolaban
2050mg/kg PO
Bupivacaine hydrochloride
Marcaine
0.5mg/kg epidural
1mg/kg total dose for local nerve block
Buprenorphine
Temgesic

0.005mg/kg q48h IV, IM

Buspirone
BuSpar
Cat: 2.55mg/cat q1224h PO
Appendix 1945
Butorphanol
Torbutrol
Torbugesic
Dog: Analgesic: 0.10.2mg/kg IV, 0.10.4mg/kg
IM
or SC Antitussive: 0.551.1mg/kg PO q612h,
0.0550.11mg/kg SC q612h
Cat: Analgesic: 0.050.2mg/kg IV, 0.10.3mg/kg
IM,
SC
Calcitonin
Calcimar
46IU/kg SC initially q12h, then q8h for
hypercalcemia
Calcitriol
Rocaltrol
23 ng/kg/d divided q12h for 34 days, then 12
ng/kg/d
maintenance
Calcium carbonate
2550mg/kg/d PO
Camalox
60100mg/kg/d (in divided doses) as phosphate
binder
Calcium chloride (10% solution)
Hypocalcemia: 515mg/kg/h IV
Calcium citrate
Cat: 1030mg/kg q8h (with meals) PO
Calcium disodium EDTA
See Edetate calcium disodium (CaNa2, EDTA)
Calcium gluconate (10% solution)
0.51.5 ml/kg IV (slowly)
Calcium gluconate tablets
2550mg/kg/day PO
Calcium lactate
2550mg/kg/d PO
Captan
0.25% solution topically, 23 times/wk
Captopril
Capoten
Dog: 0.52.0mg/kg q812h PO
Cat: 3.126.25mg/cat q8h PO
Carbenicillin disodium

Geopen
Pyopen
4050mg/kg q68h IV, IM, SC
Carbenicillin indanyl sodium
Geocillin
Urinary tract infections: 10mg/kg q8h PO
Carbimazole
Neo-mercazole
Cat: 5mg/cat q8h PO (induction), followed by
5mg/cat q12h PO
Carboplatin
Paraplatin
Dog: 250300mg/m2 q3wk IV
Cat: 150250mg/m2 q4wk IV
Carnitine
See Levo-carnitine
Carprofen
Rimadyl
Dog: 2mg/kg q12h PO
Carvedilol
Coreg
See Chapter 146
Castor oil
Dog: 830ml/dog qd PO
Cat: 410ml/cat qd PO
Cefadroxil
Cefa-Tabs
Cefa-Drops
Dog: 22mg/kg q12h PO
Cat: 22mg/kg q24h PO
Cefazolin sodium
Ancef
Kefzol
2025mg/kg q68h IV, IM
Cefepime
Maxipime
Dog: 40 mg/kg q6h IM, IV
Cefmetazole sodium
Zefazone
15mg/kg q8h IV, IM, SC
Cefotaxime sodium
Claforan
2080mg/kg q6h IV, IM
Cefoxitin sodium
Mefoxin
1530mg/kg q68h IV
Ceftazidime
Fortaz

30 mg/kg q6h IV, IM

Ceftiofur
Naxcel
Dog: 2.24.4 mg/kg q24h SC
Cephalexin
Keflex
1030mg/kg q612h PO
Cephalothin sodium
Keflin
1030mg/kg q48h IV, IM
Cephapirin sodium
Cefadyl
1030mg/kg q48h IV, IM
Cephradine
Velosef
1025mg/kg q68h PO
Charcoal, activated
Acta-Char
SuperChar Vet/Powder or Vet/Liquid
Toxiban
14 g/kg PO (granules)
612ml/kg PO (suspension)
Chlorambucil
Leukeran
24mg/m2 q48h PO (see Chap. 26)
Cats (FIP): 20mg/m2 q23 wk PO
Chronic lymphocytic leukemia
20mg/m2 q12wks PO or 6mg/m2/day
Chloramphenicol
Chloromycetin
Dog: 3050mg/kg q68h IV, IM PO
Cat: 3050mg/cat q12h IV, IM PO
1946 Appendix
Chlorothiazide
Diuril
2040mg/kg q12h PO
Chlorpheniramine maleate
Phenetron
Chlor-Trimeton
Dog: 0.4mg/kg q812h PO
Cat: 2mg/cat q12h PO
Chlorpromazine
Thorazine
0.5mg/kg q68h IM, SC, PO
Prior to cancer chemotherapy: 2mg/kg q3h SC
Chlortetracycline
25mg/kg q68h PO
Cholecalciferol (vitamin D3)

5002000U/kg/d PO (1 mg = 40,000U)
Chorionic gonadotropin
See Gonadotropin, chorionic (hCG)
Cimetidine
Tagamet
510mg/kg q68h IV, IM, PO
Renal failure: 2.55.0mg/kg q12h IV, PO
Ciprofloxacin
Cipro
515mg/kg q12h PO
Cisapride
Propulsid
Dog: 0.250.5mg/kg q812h PO
Cat: 2.55mg q812h PO
Cisplatin
Platinol
5070mg/m2 q3wk IV drip (requires aggressive
diuresis); do
not use in cats
Clarithromycin
Biaxin
5mg/kg q12h PO
Clavamox
See Amoxicillin plus clavulanate
Clavulanate
See Amoxicillin plus clavulanate
Clemastine
Tavist, Contac 12-Hr Allergy
Dog: 0.050.1mg/kg q12h PO
Clindamycin
Antirobe
Cleocin
Dog: 510mg/kg q8h PO, IV, IM
Cat: 5.5 mg/kg q12h, or 11mg/kg q24h
(staphylococcal infections) PO; 11 mg/kg q12h,
or
22mg/kg q24h PO(anaerobic infections) PO
Toxoplasmosis: 2550 mg/kg/d PO (in divided
treatments)
for 23 weeks
Clofazimine
Lamprene
10mg/kg q24h PO
Clomipramine
Anafranil, Clomicalm
1mg/kg q1224h PO up to a maximum dose of
3mg/kg
q1224h PO

Clonazepam
Klonopin
0.5mg/kg q12h PO
Clorazepate dipotassium
Tranxene
2mg/kg q12h PO
Clotrimazole (1%)
Lotrimin
Topical intranasal infusion; 5060 ml per side
over
1 hour via indwelling catheter (for aspergillosis,
penicilliosis)
Cloxacillin sodium
Cloxapen
Orbenin
Tegopen
2040mg/kg q8h PO
Cod liver oil
1 tsp/10 kg once daily PO
Codeine
Dog: Analgesic: 0.51.0mg/kg q68h PO
Antitussive: 12mg/kg q612h PO
Colchicine
0.0250.03mg/kg q24h PO
Corticotropin gel (ACTH)
Acthar
Response test: collect pre-ACTH sample and
inject 2.2
IU/kg IM; collect post-ACTH sample at 2 hours in
dogs
and at 1 and 2 hours in cats
Cosyntropin
Cortrosyn
Response test: collect pre-ACTH sample and
inject 5mg/kg
IV in dogs and 125mg IV in cats; collect postACTH
sample at 1 hour
Cyanocobalamin (vitamin B12)
Dog: 100200mg/dog qd PO
Cat: 50100mg/cat qd PO
Cyclophosphamide
Cytoxan
Anticancer therapy: 50mg/m2 q48h PO, or
50mg/m2 once
daily 4 days/week PO, or 100300mg/m2 IV and
repeat in
21 days (see Chap. 26)

Immunosuppressive therapy: 50mg/m2 q48h PO

(see Chap. 24)
Cat: 200mg/m2 q23wk PO (see Chap. 26)
Cyclosporine
Sandimmune, Neoral, Optimmune ointment
Dog: 10mg/kg q12h PO
Cat: 5mg/kg q12h PO to 15mg/kg q24h (adjust
dose
via monitoring)
Perianal fistulae: 1.753.0mg/kg q12h PO
Topical treatment for keratoconjunctivitis sicca:
12%
solution in oil: instill 1 drop in eye q12hr
Cyclothiazide
Anhydron
0.51.0mg/kg q24h PO
Cyproheptadine
Periactin
Antihistamine: 0.51.0mg/kg q12h PO
Appetite stimulant in cat: 2mg/cat q12h PO
Appendix 1947
Cytosine arabinoside
Cytosar
Dog: 100mg/m2 once daily for 4 days IV, SC
(lymphoma) q34wk (see Chap. 26)
Cat: 100mg/m2 IV or SC once daily for 2 days
(see
Chap. 26)
Dacarbazine
DTIC
Dog: 1000mg/m2 IV drip for 68 hours, repeat
q3wk
(see Chap. 30)
Danazol
Danocrine
510mg/kg q12h PO
Dantrolene sodium
Dantrium
Dog: 15mg/kg q8h PO
Cat: 0.52.0mg/kg q12h PO
Dapsone
1.1mg/kg q8h PO
Deferoxamine mesylate
Desferal
10mg/kg IV, IM q2h for 2 doses, then 10 mg/kg
q8h for 24
hours

Delta-Albaplex (novobiocin plus prednisolone

plus
tetracycline hydrochloride)
Dog 37kg: 12 tablets/d PO
Dog 714kg: 24 tablets/d PO
Dog 1427kg: 46 tablets/d PO
Dog >27kg: 68 tablets/d PO
Cat: 1 tablet q12h PO
Deprenyl (L-deprenyl, selegiline)
Anipryl
Dog: 1mg/kg q24h PO
Deracoxib
Deramaxx
Dog: 34 mg/kg q24h PO for 7 days
Derm Caps (omega fatty acid)
1 capsule/9.1 kg daily PO
Desmopressin acetate
DDAVP
Diabetes insipidus: 24 drops q1224h
intranasally
von Willebrands disease: 1.0mg/kg SC, IV,
diluted in 20ml
saline over 10 minutes
Desoxycorticosterone pivalate (DOCP)
Percorten-V
1.52.2mg/kg q25d IM
Dexamethasone
Azium
Anti-inflammatory: 0.10.2mg/kg q1224h IV,
IM, PO
Shock: 2.24.4mg/kg IV
Dexamethasone sodium phosphate
Shock: 12mg/kg IV
Dextran-70
Gentran-70
1020ml/kg IV q24h to effect
Dextromethorphan
Benylin DM and others
0.52.0mg/kg q68h PO
Dextrose (5% solution)
4050ml/kg q24h IV
Diazepam
Valium
Preanesthetic: 0.10.25mg/kg IV, IM, SC
Status epilepticus: 0.250.5 mg/kg IV; repeat if
necessary; 1
mg/kg rectally

Appetite stimulant in cat: 0.10.2 mg/kg IV

(q1224h as
needed)
Functional urethral obstruction in dogs: 2
10mg/dog q8h
PO
Urinary disorder in cat: 1.252.5mg/cat q812h
PO
Diazoxide
Proglycem
10 mg/kg q12h PO, do not exceed 60mg/kg/d
Diclorophene
See Toluene
Dichlorphenamide
Daranide
24mg/kg q812h PO
Dichlorvos
Performer
Dog: 26.433mg/kg PO
Cat: 11mg/kg PO
Dicloxacillin
Dynapen
1155mg/kg q8h
Dicyclomine
Bentyl
0.2 mg/kg q812h PO
Diethylcarbamazine
Caricide
Filaribits
Heartworm prophylaxis: 6.6mg/kg q24h PO
Diethylstilbestrol (DES)
Urinary incontinence (dog): 0.11.0mg/dog
q24h PO for 3
days, then 1mg/wk PO
Digitoxin
Crystodigin
0.020.03mg/kg q8h PO
Digoxin
Lanoxin
Cardoxin
Dog: 0.22mg/m2 q12h PO, 0.00550.01mg/kg
q12h
PO, (reduce dose by 10% for elixir)
Cat: 0.01 mg/kg q48h, 0.007 mg/kg q48h (with
Lasix
and aspirin)
Dihydrotachysterol (vitamin D)
Hytakerol

DHT
Initial: 0.020.03mg/kg/day PO maintenance:
0.010.02mg/kg q2448h PO
Diltiazem hydrochloride
Cardizem
Dog: 0.51.5mg/kg q8h PO
Cat: 1.752.4mg/kg q812h PO
Dilacor XR
Cat: 30mg/cat q1224h PO
Cardizem CD
Cat: 10mg/kg q24hr PO
Dimenhydrinate
Dramamine (U.S.)
1948 Appendix
Gravol (Canada)
Dog: 48mg/kg q8h IV, IM, PO
Cat: 12.5 mg q8h IV, IM, PO
Dimercaprol
BAL in oil
4mg/kg q4h IM
Dinoprost tromethamine
See Prostaglandin F2a
Dioctyl calcium sulfosuccinate
See Docusate calcium
Dioctyl sodium sulfosuccinate
See Docusate sodium
Diphenhydramine hydrochloride
Benadryl
2.2mg/kg q812h IV, IM, PO
Diphenoxylate hydrochloride
Lomotil
Dog: 0.10.2mg/kg q812h PO
Cat: 0.050.1mg/kg q12h PO
Diphenylhydantoin
See Phenytoin
Diphosphonate disodium etidronate
See Etidronate disodium
Dipyridamole
Persantine
410mg/kg q24h PO
Disopyramide phosphate
Norpace
Dog: 615mg/kg q8h PO
Dithiazanine iodide
Dizan
6.611.0 mg/kg q24h PO for 710 days
Divalproex sodium
Depakote

Equivalent to valproic acid (see Valproic acid)

Dobutamine
Dobutrex
Prepare 250 mg in 1 L 5% dextrose
Dog: 2.520mg/kg/min IV infusion
Cat: 2.55.0mg/kg/min IV infusion
Docusate calcium
Surfak
Doxidan
Dog: 50100mg/dog q1224h PO
Cat: 50mg/cat q1224h PO
Docusate sodium
Colace
Dog: 50200mg/dog q812h PO
Cat: 50mg/cat q1224h PO
Dopamine hydrochloride
Intropin
210mg/kg/min IV infusion (prepare 40 mg in
500ml
lactated Ringers solution)
Doxapram hydrochloride
Dopram
510mg/kg IV
Neonate: 15 mg SC, sublingually, or via
umbilical vein
Doxorubicin
Adriamycin
Dogs 10kg and cats: 2025mg/m2 IV q3wk
Dogs > 10kg: 30mg/m2 IV q3wk (maximum
cumulative
dose 180240mg/m2) (see Chap. 26)
Doxycycline
Vibramycin
35mg/kg q12h PO
Lyme borreliosis:
10mg/kg q12h PO
Edetate calcium disodium (CaEDTA)
Havidote
25mg/kg q6h SC for 25 days
Edrophonium chloride
Tensilon
Dog: 0.110.22mg/kg IV
Cat: 2.5mg/cat IV
Enalapril maleate
Enacard
Dog: 0.5mg/kg q1224h PO
Cat: 0.250.5mg/kg q1224h PO
Enflurane

Ethrane
23% (induction); 1.53% (maintenance)
Enilconazole
Imaverol
Nasal aspergillosis: 10 mg/kg q12h instilled into
nasal sinus
for 1014 days (10% solution diluted 50 : 50
with water)
Dermatophytes: solution diluted to 0.2% and
lesion washed
with solution 4 times at 3- to 4-day intervals
Enrofloxacin
Baytril
2.55.0 mg/kg q12h PO, IM, SC, or 510mg/kg
q24h PO,
IM
Ephedrine
Urinary incontinence
Dog: 515mg/dog q8h PO
Cat: 24mg/cat q8h PO
Bronchodilator: 12mg/kg q8h PO
Epinephrine
Adrenalin
20mg/kg, or 0.10.5 ml of 1:1000 (1 mg/ml)
solution; or 15
ml of a 1:10,000 (0.1 mg/ml) solution IV, IM, SC,
IC,
intratracheally
Epogen
35100 IU/kg q48h SC until PCV rises, then
weekly
Epsiprantel
Cestex
Dog: 5.5mg/kg PO
Cat: 2.75mg/kg PO
Epsom salt
See Magnesium sulfate
Ergocalciferol (vitamin D2)
Calciferol
Initial: 40006000U/kg/d PO
Maintenance: 10002000U/kg q24hq7d PO
(see
Chap. 32)
Erythromycin
Antibiotic: 1020mg/kg q812h PO
Promotility: 0.51.0mg/kg q8h PO
Erythropoietin (r-HuEPO)
Epogen

Appendix 1949
75100U/kg SC 3 times weekly (adjust dose to
reach and
maintain hematocrit of 3034%)
Esmolol
Brevibloc
Dog: 50500mg/kg IV bolus every 5 minutes (up
to
500mg/kg)
Essential fatty acids
(See also Omega fatty acids)
EFA-Z Plus
<6.7 kg: 3.7ml/d PO
6.722.5 kg: 7ml/d PO
>22.5 kg: 14ml/d PO
Estradiol cypionate (ECP)
Depo-Estradiol
Dog: 0.020.04 mg/kg IM (total dose not to
exceed
1.0 mg) within 3 days of mating
Cat: 0.25 mg/cat IM within 3 days of mating
Use of ECP for mismating is discouraged
Ethanol (20%)
For ethylene glycol toxicity:
Dogs: 5.5 ml/kg IV q4h for 5 treatments, then
q6h for 4
treatments
Cats: 5.0 ml/kg IV q6h for 5 treatments, then
q8h for 4
treatments
Ethoxzolamide
Cardrase
Glaucoma: 4mg/kg q812h PO
Etidronate disodium
Didronel
510mg/kg q1224h PO
Etodolac
Dog: 1015mg/kg q24h PO
Etomidate
14mg/kg IV
Etretinate
Tegison
Dog: 0.751mg/kg q24h PO
Cat: 2mg/kg q24h PO
Famotidine
Pepcid
0.51.0 mg/kg q1224h IM, SC, IV, PO
Febantel

Rintal
10mg/kg q24h for 3 days PO
Febantel plus praziquantel
RM-Parasitacide; Drontal-Plus
15mg/kg FEB 1.5mg/kg PRA, PO, for 3 days
Felbamate
Initially 20mg/kg q8h PO (maximum dose:
3000mg/d)
(see Chap. 127)
Fenbendazole
Panacur
50mg/kg/d for 3 days PO
Fentanyl
Sublimaze
0.020.04mg/kg IV, IM, SC, or 0.01mg/kg IV, IM,
SC
(with acetylpromazine or diazepam)
Analgesia: 0.0020.005 mg/kg IV; 0.004
0.008mg/kg
IM, SC
Fentanyl transdermal patch
Duragesic
Dog: <10kg, 25mg/h, q72h 1020kg, 50mg/h,
q72h
2030kg, 75mg/h, q72h >30kg, 100mg/h, q72h
Cat: 25mg/h, q118h
Ferrous sulfate
Dog: 100300mg/dog q24h PO
Cat: 50100mg/cat q24h PO
Flavoxate
Urispas
100200 mg q1224h PO
Florifenicol
Nuflor
Dog: 20 mg/kg q6h PO, IM
Cat: 22 mg/kg q8h PO, IM
Fluconazole
Diflucan
2.55.0 mg/kg q1224h PO or IV (double loading
dose on
day 1)
(for CNS Cryptococcus: 1015mg/kg q1224h)
Flucytosine
Ancobon
Cryptococcosis: 50mg/kg q8h or 75mg/kg q12h,
PO
combined with Amphotericin B
Fludrocortisone acetate

Florinef Acetate
Dog: 0.20.8mg/dog (0.02mg/kg) q24h PO
Cat: 0.1mg/cat q24h PO
Flumethasone
Flucort
Dog: 0.06250.25mg/dog q24h IV, IM, SC, PO
Cat: 0.030.125mg/cat q24h IV, IM, SC, PO
Anti-inflammatory: 0.150.3mg/kg q1224h IV,
IM, SC, PO
Flunixin meglumine
Banamine
1.1mg/kg once IV, IM, SC, or 1.1 mg/kg/d for 3
days/wk
PO
Ophthalmic: 0.51.0mg/kg once IV
Fluorouracil
5-Fluorouracil
Dog: 150200mg/m2 q7d IV
Cat: do not use
Fluoxetin
Prozac
Dog: 0.51.0mg/kg q24h PO
Cat: 0.54mg/cat q24h PO
Folic acid
Folvite
Dog and cat: 0.0040.01mg/kg/d (410mg/kg/d)
Follicle-stimulating hormone (FSH)
See Urofollitropin
Furazolidone
Furoxone
4mg/kg q12h for 710 days PO
Furosemide
Lasix
Dog: 26mg/kg q812h (or as needed) IV, IM,
SC,
PO
Cat: 14mg/kg q12h IV, IM, SC, PO
1950 Appendix
Gabapentin
3060 mg/kg/d PO (divide bid or tid)
Gentamicin sulfate
Gentocin
Dog: 24mg/kg q68h IV, IM, SC, or 6mg/kg
q24h
Cat: 3mg/kg q8hr IV, IM, SC
Glipizide
Glucotrol
Cat: 2.55 mg/cat q812h with food

Glucosamine chondroitin sulfate

Cosequin and others
Dog: 12 RS (Regular Strength) capsules/d (24
capsules of DS (Double Strength) for large dogs)
Cat: 1 RS capsule/d
Glyburide (Glibenclamide)
Diabeta
Micronase
0.2mg/kg daily PO
Glycerin
Glyrol
Osmoglyn
Glaucoma: 11.5 gm/kg PO initially, then
500mg/kg q8h;
or 12 ml of 50% solution q8h
Glycopyrrolate
Robinul-V
0.0050.01mg/kg IV, IM, SC q812h as needed
Gold sodium thiomalate
Myochrysine
Immune-mediated arthritis: 1mg/kg once weekly
IM
Gonadorelin (GnRH, LHRH)
Factrel
Dog: 50100mg/dog q2448h IM
Cat: 25mg/cat once IM
Gonadotropin, chorionic (hCG)
Follutein
Dog: 22U/kg q2448h IM, or 44U/kg once IM
Cat: 250U/cat once IM
Gonadotropin-releasing hormone
See Gonadorelin
Griseofulvin (microsize)
Fulvicin U/F powder or tablets
50mg/kg q24h PO (maximum dose: 110
132mg/kg/d in
divided treatments)
Griseofulvin (ultramicrosize)
Fulvicin P/G
510mg/kg/d PO (in divided treatments)
Growth hormone
0.1 U/kg 3 times/wk for 46 weeks
Halothane
Fluothane
3% (induction); 0.51.5% (maintenance) (see
Chap. 2)
Heparin sodium
Liquaemin (U.S.)

Hepalean (Canada)
100200U/kg IV, loading dose; then 100
300U/kg q68h
SC (monitor clotting profiles)
Low-dose therapy (dog and cat): 70U/kg q812h
SC
Hetacillin potassium
Hetacin-K
2040mg/kg q8h PO
Hetastarch
See Hydroxyethyl starch
Hydralazine
Apresoline
Dog: 0.5 mg/kg (initial dose), titrated to 0.52.0
mg/kg q12h PO
Cat: 2.55mg/cat q1224h PO
Hydrochlorothiazide
Hydrodiuril
24mg/kg q12h PO
Hydrocodone
Hycodan
Dog: 0.22mg/kg q612h PO
Hydrocortisone
Cortef
Replacement therapy: 1mg/kg q12h PO
Anti-inflammatory: 2.55.0mg/kg q12h PO
Hydrocortisone sodium succinate
Solu-Cortef
Shock: 50150mg/kg IV
Hydromorphone
0.10.2mg/kg IV, IM, SC
Hydroxyethyl starch
Hetastarch
Dog: 20ml/kg/24h (5ml/kg over 15 min for
hypovolemia) (see Chap. 5)
Cat: 10ml/kg/24h (2.5ml/kg over 15 min for
hypovolemia) (see Chap. 5)
Hydroxyurea
Hydrea
For polycythemia vera: 30 mg/kg/d for 1 week,
then
15mg/kg/d until remission
Hydroxyzine
Atarax
Dog: 2.2mg/kg q812h PO
Cat: 10mg/cat q12h PO
Hyoscyamine
0.0030.006mg/kg q812h PO, SC

Imidocarb
5mg/kg IM SC once and repeated in 14 days
Imipramine
Dog: 1mg/kg q8h PO
Cat: 2.55.0mg/cat q12h PO
Insulin (NPH isophane)
Dog: 0.51.0 U/kg q1224h SC (to effect)
Cat: 15U/cat q12h SC (to effect) (see Chap. 34)
Insulin (PZI)
Dog: 0.51.0 U/kg q1224h SC (to effect)
Cat: 15 units/cat (0.21.0U/kg) q1224h SC
(adjust with monitoring) (see Chap. 34)
Insulin (regular crystalline)
Ketoacidosis:
See Chapter 34 for complete treatment protocol
Insulin, ultralente
Dog: 0.51.0 U/kg q1224h SC (to effect)
Cat: 15U/cat q1224h SC (to effect) (see Chap.
34)
Interferon-alpha
Roferon A; Intron A (dilute to 30U/ml)
Cat: 30U/cat q24h for 7 days on alternating
weeks
Appendix 1951
Interferon-omega (recombinant feline [rFeIFNomega])
Virbagen
FIP: 1,000,000 u/kg SC (See Chapters 810 and
14 for
treatment protocols)
Iodide
See Potassium iodide
Ipecac syrup
Dog: 12ml/kg up to 15ml PO
Cat: 26ml/cat PO
Iron
See Ferrous sulfate
Isoflurane
3.5% (induction); 1.52.5% (maintenance)
(see Chap. 2)
Isoproterenol
Isuprel
0.040.09mg/kg/min IV; 0.10.2mg/dog q46h
IM, SC
Isosorbide dinitrate
Isordil
Sorbitrate
2.55mg/animal q12h PO

Isotretinoin
Accutane
13mg/kg/d (maximum dose: 34mg/kg/d) PO
Itraconazole
Sporanox
Dog: 5mg/kg q1224h PO
Cat: 510mg/kg q12h PO, or 20mg/kg q24h
Ivermectin
Heartgard
Ivomec
Heartworm preventive in dog: 6mg/kg q30d PO
Cat: 24mg/kg q30d PO
Microfilaricide in dog: 50mg/kg PO 34 weeks
after
adulticide therapy
Ectoparasite therapy: 300600mg/kg q24h IM,
SC, PO
(do not use in collie and sheltie dogs)
Respiratory parasites: 200400mg/kg weekly SC,
PO (do not
use in collie and sheltie dogs)
Kanamycin sulfate
Kantrim
10mg/kg q68h IV, IM, SC
Kaolin plus pectin
Kaopectate
12ml/kg q26h PO
Ketamine
Ketalar
Ketaset
Cat: 410mg/kg IV, 1020 mg/kg IM, SC (see
Chap 2)
Dog: 1ml/10kg IV of ketamine : diazepam
mixture
(50 : 50)
Ketoconazole
Nizoral
Dog: 1015mg/kg q12h PO (Malassezia canis
infection: 10mg/kg q24h or 5mg/kg q12h PO)
Hyperadrenocorticism: 15mg/kg q12h PO
Cat: 510mg/kg q812h PO
Ketoprofen
Ketofen
Dog: 1.1mg/kg q24h IV, PO for up to 5 days
Cat: 2mg/kg q24h PO, SC initially, then 0.51.0
PO, SC
Lactated Ringers solution
4050ml/kg/d IV for maintenance requirements

Shock therapy:
Dog: 90ml/kg IV
Cat: 60ml/kg IV
Lactulose
Cephulac; Duphalac
Constipation: 1ml/4.5kg q8h PO (to effect)
Hepatic encephalopathy
Dog: 0.5ml/kg q8h PO
Cat: 2.55.0ml/cat q8h PO
Leucovorin (folinic acid)
Wellcovorin
With methotrexate administration: 3mg/m2 IV,
IM, PO
Antidote for pyrimethamine toxicosis: 1mg/kg
q24h PO
Levamisole
Levasole
Tramisol
Dog: 58mg/kg PO once, up to 10mg/kg PO for 2
days (hookworms); 10 mg/kg q24h PO for 610
days
(microfilaricide); 0.52.0mg/kg 3 times/wk PO
(immunostimulant)
Cat: 4.4mg/kg PO once
Levetiracetem
5004000 mg/d PO (divide bid or tid)
Levo-carnitine
Dog: 50mg/kg q8h PO
Cat: 250500mg/cat qd PO
Levodopa (l-dopa)
Larodopa
Hepatic encephalopathy: 6.8 mg/kg initially,
then 1.4mg/kg
q6h
Levothyroxine sodium
Soloxine
Thyro-Tabs
Synthroid
Dog: 0.010.02mg/kg q12h, PO
Cat: 0.010.02mg/kg q24h, PO
Lidocaine
Xylocaine
Antiarrhythmia in dog: 24mg/kg IV (maximum
dose:
8mg/kg over 10 min); 2575mg/kg/min IV
infusion;
6mg/kg q1.5h IM
Cat: 0.250.75mg/kg IV, slowly

Lime sulfur (23% solution)

Topically once/wk for 46 weeks
Lincomycin
Lincocin
1525mg/kg q12h IV, IM, PO
Liothyronine
Cytobin or Cytomel
4.4mg/kg q8h PO
Suppression testing: See Chapter 31 for protocol
Lisinopril
Prinivil
Dog: 0.250.5mg/kg q1224h
Lithium carbonate
Lithotabs
Dog: 10mg/kg q12h PO
Cat: not recommended
1952 Appendix
Lomustine
6090mg/m2 q2128d PO
Loperamide
Imodium
Dog: 0.10.2mg/kg q812h PO
Cat: 0.10.3mg/kg q1224h PO
Lufenuron
Program
Flea control
Dog: 10mg/kg q30d PO
Cat: 30mg/kg q30d PO
Coccidioidomycosis
5mg/kg PO q24h
Luteinizing hormone
See Gonadorelin
Magnesium citrate
Citroma, Citro-Nesia (U.S.)
Citro-Mag (Canada)
24ml/kg PO
Magnesium hydroxide
Milk of Magnesia
Antacid: 510 ml per dog or cat PO
Cathartic:
Dog: 1550ml/dog PO
Cat: 26ml/cat q24h PO
Magnesium sulfate
Dog: 825 g/dog q24h PO
Cat: 25 g/cat q24h PO
Mannitol
Osmitrol
Diuretic: 1 g/kg of 525% solution IV

Glaucoma or CNS edema: 0.51.0 g/kg of 15

25% solution
over 1560 minutes IV (repeat in 46 hours if
necessary)
Marbofloxacin
Marbocyl, Zeniquin
Dog: 2.755.55mg/kg q24h PO
Mebendazole
Telmintic
22mg/kg (with food) q24h for 3 days
Meclizine hydrochloride
Bonine
Dog: 25mg/dog q24h PO (motion sickness:
administer 1 hour before traveling)
Cat: 12.5mg/cat q24h PO
Meclofenamic acid
Meclomen
Meclofen
Arquel
Dog: 1mg/kg/d for 5 days, then 0.5mg/kg q24h
PO
Medetomidine
Domitor
Dog: 0.0070.02 mg/kg IV; 0.010.04mg/kg IM,
SC
Cat: 0.010.03mg/kg IV; 0.030.08mg/kg IM, SC
Medium-chain triglycerides (MCTs)
MCT oil
12ml/kg daily in food
Medroxyprogesterone acetate
Depo-Provera
1.12.2mg/kg q7d IM
Megestrol acetate
Ovaban
Dog: Proestrus: 2.2 mg/kg q24h PO for 8 days
Anestrus: 0.55 mg/kg q24h PO for 30 days
Behavior
problems: 24 mg/kg q24h for 8 days (reduce
dose
for maintenance)
Cat: dermatologic therapy or urine spraying:
2.5
5.0 mg/cat q24h PO for 1 week, then reduce to
2.5
5.0 mg once or twice/wk; suppress estrus:
5mg/cat
for 3 days, then 2.55 mg once/wk for 10 weeks
Melarsomine

Immiticide
Dog: 2.5 mg/kg, IM, q24h for 2 doses, Alternate:
2.5 mg/kg, IM once; then after 12 months give
2.5 mg/kg IM, q24h for 2 additional doses
Meloxicam
Metacam
Dog: 0.2 mg/kg PO, SC initially, then 0.1 mg/kg
q24h
for 23 days
Cat: 0.3 mg/kg SC, one time only
Melphalan
Alkeran
24mg/m2 q2448h PO (see Chap. 26)
Meperidine
Demerol
Dog: 0.42mg/kg IV, 1.04.0mg/kg IM, SC
6-Mercaptopurine
Purinethol
50mg/m2 q24h PO
Mesalamine
Asacol; Pentasa
Dogs: 20mg/kg q812h PO
(See also Osalazine sodium; Sulfasalazine)
Metaproterenol
Alupent
Metaprel
0.3250.65mg/kg q46h PO
Metaraminol bitartrate
Aramine
0.1mg/kg IM, SC
Methazolamide
Neptazane
24mg/kg q812h PO
Methenamine hippurate
Hiprex
Dog: 500mg/dog q12h PO
Cat: 250mg/cat q12h PO
Methenamine mandelate
Mandelamine
1020mg/kg q812h PO
Methimazole
Tapazole
Cat: 2.5 mg/cat q812h PO (initial), increase to
510mg/cat q812h PO by monitoring T4
Methionine (l-methionine, dl-methionine)
Uroeze
Methio-Form
Dog: 150300mg/kg/d PO

Cat: 10001500mg/cat PO (added to food each

day)
(use in adult cats only)
Appendix 1953
Methocarbamol
Robaxin-V
44mg/kg q8h PO on the first day, then 22
44mg/kg q8h
PO
Methotrexate (MTX)
2.5mg/m2 q24h PO; or 23 times per week;
1520mg/m2 IV q3wk (see Chap. 26)
Methoxamine
Vasoxyl
200250mg/kg IM, or 4080mg/kg IV
Methscopolamine bromide
Pamine
0.31.0 mg/kg q8h PO (use cautiously in cats)
Methylene blue (1% solution)
Dog: for pancreatic tumor identification: 3mg/kg
IV
slowly, diluted in isotonic saline (can cause
hemolytic
anemia)
Cat: do not use
Methylprednisolone
Medrol
Dog: 0.220.44mg/kg q1224h PO
Methylprednisolone acetate
Depo-Medrol
Dog: 1mg/kg IM q13wk
Cat: 1020mg/cat IM q13wk
Methylprednisolone sodium succinate
Solu-Medrol
For spinal cord trauma: 30mg/kg IV, repeat at
15mg/kg IV
in 26 hours
4-Methylpyrazole (fomepizole)
Antizol-Vet
20mg/kg initially IV, then 15 mg/kg at 12- and
24-hour
intervals, then 5 mg/kg at 36h.
Methyltestosterone
Android
Fluoxymestrone
Dog: 1.0mg/kg q48h PO
(see also Testosterone cypionate; Testosterone
propionate),

for sex hormone dematoses in dogs: 1 mg/kg

(up to
30mg total dose)
Cat: 1.02.5mg/cat q48h PO
Metoclopramide
Reglan
Maxolon
0.20.5mg/kg q68h IV, IM, SC, PO, or 12mg/kg
q24h via
continuous IV infusion
Metoprolol tartrate
Lopressor
Dog: 550mg/dog q8h PO
Cat: 215mg/cat q8h PO
or: 0.251.0mg/kg q8h PO (dog and cat)
Metronidazole
Flagyl
Dog: for giardia: 5065 mg/kg q24h PO for 57
days;
Antibacterial: 1015mg/kg q812h PO
Cat: for giardia: 50 mg/kg q24h PO for 5 days;
Antibacterial: 10mg/kg q8h or 15mg/kg q12h PO
Mexiletine
Mexitil
Dog: 58mg/kg q812h PO (use cautiously)
Mibolerone
Cheque
Dog: (2.65.0mg/kg/d PO) 0.4511.3 kg: 30mg
11.822.7 kg: 60mg 2345.3 kg: 120mg >45.8
kg: 180mg
Cat: safe dose not established
Midazolam
Versed
0.10.25mg/kg IV, IM, or 0.10.3 mg/kg/h IV
infusion
Milbemycin oxime
Interceptor
Dog: 0.5mg/kg q30d PO
For demodex: 12mg/kg q24h PO
For scabies: 2 mg/kg PO twice at 14-day
intervals
Milk of magnesia
See Magnesium hydroxide
Milk thistle
Marin
6100mg q24h PO
Minocycline
Minocin

5.012.5mg/kg q12h PO
Misoprostol
Cytotec
Dog: 35mg/kg q68h PO
Mitotane (o,p-DDD)
Lysodren
For pituitary-dependent hyperadrenocorticism:
50mg/kg/d
PO (may be given in divided doses) for 510
days, then
5070mg/kg/wk PO
Adrenal tumor: 5075 mg/kg/d for 10 days PO,
then 75100
mg/kg/wk PO (see Chap. 33)
Mitoxantrone
Novantrone
56mg/m2 IV q3wk
Morphine
Dog: 0.20.6 mg/kg IM, SC (as needed);
0.1mg/kg
epidural
Cat: 0.1 mg/kg IM, SC (as needed)
Nadolol
Corgard
0.250.5mg/kg q12h PO
Nafcillin sodium
Unipen
10mg/kg q6h IM, PO
Nalbuphine
Dog: 0.52.0mg/kg IV, IM, SC
Cat: 0.51.5mg/kg IV, IM, SC
Nalorphine
Nalline
0.44mg/kg IV, IM, SC (1 mg for every 10 mg of
morphine)
Naloxone
Narcan
0.0030.01mg/kg IV, IM, for opiate reversal
Naltrexone hydrochloride
Trexan
Behavior problems: 2.2mg/kg q12h PO
Nandrolone decanoate
Deca-Durabolin
Dog: 1.01.5mg/kg qwk IM
Cat: 1mg/cat qwk IM
1954 Appendix
Neomycin
Biosol

1020mg/kg q612h PO
Neostigmine bromide
Prostigmin bromide
2mg/kg/d PO (in divided doses, to effect)
Neostigmine methylsulfate
Prostigmin
Antimyasthenic: 10mg/kg IM, SC, as needed
(atropine may
be administered to counteract side effects)
Antidote for curiform block: 40mg/kg IM, SC
(administer
with atropine)
Diagnostic aid for myasthenia gravis: 40mg/kg
IM, or
20mg/kg IV
Nitrofurantoin
Furadantin
Macrodantin
4mg/kg q8h PO
Nitroglycerin ointment
Nitrol Ointment
Nitro-Bid Ointment
Nitrostat Ointment
(1 inch of ointment is approximately 15 mg)
Dog: 1/41 inch topically q1224h
Cat: 1/4 inch topically q1224h
Nitroprusside
Nipride
2.515mg/kg/min constant IV infusion
Nizatidine
Axid
2.55mg/kg q24h PO
Norfloxacin
Noroxin
22mg/kg q12h PO
Novobiocin
See Delta-Albaplex
Olsalazine
Dipentum
Dog: 2030mg/kg q812h PO
Omega fatty acids
See also Derm Caps
1 capsule q12h PO (see also Essential fatty acids)
Omeprazole
Prilosec
Dog: 20mg/dog or 0.71.0mg/kg q24h PO
Cat: Not recommended
Ondansetron

Zofran
0.10.5mg/kg q612h IV, SC
0.51.0mg/kg q612h PO
o,p-DDD
See Mitotane
Ormetroprim
See Primor
Oxacillin
Prostaphlin
Bactocill
2240mg/kg q8h PO
Oxazepam
Serax
Appetite stimulant: 2.5mg/cat q12h PO
Oxtriphylline
Choledyl SA
Dog: 47mg/kg (equivalent to 30 mg/kg
theophylline)
q12h PO
Oxybutynin chloride
Ditropan
5.0mg/dog q812h PO
Oxymetholone
Anadrol
15mg/kg q24h PO
Oxymorphone hydrochloride
Numorphan
Analgesia:
Dog: 0.050.1mg/kg IV 0.10.3mg/kg IM, SC
Cat: 0.010.04mg/kg IV 0.050.1mg/kg IM, SC
For preanesthesia or sedation: see Chapter 2
Oxytetracycline
Terramycin
20mg/kg q8h PO; 7.510.0mg/kg q8h IV
Oxytocin
Dog: 520 units/dog IM, repeat q30min for
primary
inertia
Cat: 35 units/cat IM
2-PAM
See Pralidoxime chloride
Pamidronate
Aredia
1.32.0 mg/kg in 150 ml 0.9% saline in 2-hour IV
infusion;
can repeat in 13 weeks
Pancreatic enzyme (pancrelipase)
Viokase

Pancrezyme
2 tsp per 20 kg body weight, or 13 tsp/0.45 kg
of food,
mixed with food 20 minutes prior to feeding
Pancuronium bromide
Pavulon
0.1mg/kg IV
Pantoprazole
Protonix
0.71.0 mg/kg q24h IV, PO
Paregoric
Corrective Mixture
0.050.06mg/kg q12h PO (5ml of paregoric
corresponds to
approximately 2 mg of morphine)
D-Penicillamine
Cuprimine
1015mg/kg q12h PO
Penicillin G potassium
20,00040,000 U/kg q68h, IV, IM
Penicillin G procaine
20,00040,000U/kg q1224h IM
Penicillin G sodium
20,00040,000U/kg q68h IV, IM
Penicillin V
10mg/kg q8h PO
Pentazocine
Talwin
Dog: 1.653.3mg/kg q4h IM
Cat: 2.23.3mg/kg IV, IM, SC
Appendix 1955
Pentobarbital
Anesthesia: 2530 mg/kg IV (first 1/2 of the
dose
administered rapidly, then remaining
administered to
effect)
Pentoxifylline
Trental
1015mg/kg q8h PO
Petrolatum, white (flavored)
Laxatone
Cat: 15ml/cat q24h PO
Phenobarbital
Luminal
Dog: 28mg/kg q12h PO
Cat: 12mg/kg q12h PO

For seizures: Initially: 2.5mg/kg q12h PO (see

Chap. 127)
and adjust by plasma concentration
Status epilepticus (dog or cat): 1020 mg/kg IV
(to effect)
or IV loading protocol (preferred; see Chap. 127)
Phenoxybenzamine hydrochloride
Dibenzyline
Dog: 0.250.5mg/kg q8h PO
Cat: 2.5mg/cat q812h PO
Phentolamine mesylate
Regitine (U.S.)
Rogitine (Canada)
0.020.1 mg/kg IV (as needed to maintain
normal blood
pressure)
Phenylbutazone
Butazolidin
Dog: 1015mg/kg q8h PO (maximum dose:
800 mg)
Cat: not recommended
Phenylephrine hydrochloride
Neo-Synephrine
0.01mg/kg q15min IV
0.1mg/kg q15min IM, SC
Phenylpropanolamine hydrochloride
Propagest
Dexatrim
Dog: 12mg/kg q12h PO
Cat: 1mg/kg q12h PO
Phenytoin
Dilantin
Antiepileptic in dog: 2035mg/kg q8h PO
Antiarrhythmic in dog: 30mg/kg q8h PO or
10mg/kg IV
over 5 minutes
Phytonadione
See Vitamin K1
Phytomenadione
See Vitamin K1
Pimobendan
Vetmedin
Dog: 0.30.6mg/kg/d divided q12h PO
Piperazine
4466mg/kg PO once
Piroxicam
Feldene
Dog: 0.3 mg/kg q48h PO (use cautiously)

Cat: dosage not established

Polyethylene glycol electrolyte solution
GoLYTELY
25ml/kg, then repeat in 24 hours PO
Polysulfated glycosaminoglycans
Adequan
12mg/kg IM once every 4 days for 7 injections
Potassium bromide
Dog and cat: 30 mg/kg q24h PO (in food) (see
Chap.
127)
Potassium chloride
0.5 mEq/kg/d (do not administer at a rate faster
than
0.5 mEq/kg/h)
1040 mEq/500ml of fluids, depending on
serum potassium
(see Chap. 5)
Potassium citrate
Urocit-K
Dog: 5075mg/kg q12h PO
Potassium gluconate
Kaon elixir
Tumil-K
2.2 mEq/100 kcal of energy/day PO
Cat: 26 mEq/cat daily PO
Potassium iodide
30100mg/cat daily (in single or divided doses)
for 1014
days
Potassium (or sodium) phosphate (potassium or
sodium)
0.010.03 mmol phosphate/kg/hr for 36 hours
(or,
2.5 mg/kg over 6 hours) (3mmol/ml or 93mg/ml
phosphate)
Pralidoxime chloride (2-PAM)
Protopam Chloride
Organophosphate toxicosis: 20 mg/kg q812h
(initial dose
slow IV, or IM; subsequent doses IM, SC)
Praziquantel
Droncit
Dog (PO): <6.8 kg: 7.5mg/kg once >6.8 kg:
5mg/kg
once
Dog (IM, SC): 2.3 kg: 7.5mg/kg once 2.74.5
kg:

6.3mg/kg once 5kg: 5mg/kg once

Cat (PO): <1.8 kg: 6.3mg/kg once >1.8 kg:
5mg/kg
once
Cat (IM, SC): 5 mg/kg IM, SC paragonimiasis:
25mg/kg q8h for 2 days
Liver flukes: 20 mg/kg qd for 3 days; PO, SC
Prazosin
Minipress
0.52.0mg/animal q812h PO
Prednisolone
Anti-inflammatory:
Dog: 0.51.0mg/kg q1224h IV, IM, PO initially
then
taper to q48h
Cat: 2.2mg/kg q1224h IV, IM, PO initially, then
taper to q48h
Immunosuppressive (dog and cat): initially 2.2
6.6mg/kg/d
IV, IM, PO, then taper to 24mg/kg q48h
Prednisolone sodium succinate
Solu-Delta-Cortef
Shock: 1530mg/kg IV, then repeat in 46 h
CNS trauma: 1530mg/kg IV, then taper to 1
2mg/kg
q12h
1956 Appendix
Prednisone
See Prednisolone
Primidone
Mylepsin
Mysoline
Initial dosage: 510mg/kg q8h PO
Primor (ormetroprim plus sulfadimethoxine)
25mg/kg on first day, followed by 12.5mg/kg
q24h PO
Procainamide
Pronestyl
Dog: 1020mg/kg q6h PO (maximum dose:
40mg/kg); 820mg/kg IV, IM; 2550mg/kg/min
IV
infusion
Cat: 38mg/kg IM, PO q68h
Procainamide (extended-release tablets)
Procan-SR
Dog: 2050mg/kg q8h PO
Cat: 62.5mg/cat q8h PO
Prochlorperazine

Compazine
0.250.5mg/kg q68h IM, SC
Progesterone, repositol
See Medroxyprogesterone acetate
Promazine
Tranquazine
12mg/kg q68h IV, IM, PO
Promethazine hydrochloride
Phenergan
0.20.4mg/kg q68h IV, IM, PO (maximum dose:
1mg/kg)
Propantheline bromide
For detrusor hyperreflexia and urge
incontinence:
Dog: 7.530.0 mg/dog q824h PO (start low)
Cat: 7.5mg/cat q2472h PO
For diarrhea: 0.25mg/kg q812h PO
Propofol
26mg/kg IV for anesthesia (see Chap. 2)
Propranolol hydrochloride
Inderal
Dog: 2060mg/kg over 510 min q8h IV, 0.21.0
mg/kg q8h PO
Cat: 2.55.0 mg/cat (0.41.2mg/kg) q812h PO
Prostaglandin E
See Misoprostol
Prostaglandin F2a
Lutalyse
Pyometra: Dog: 0.10.25 mg/kg, once daily for
35 days SC
(see Chap. 90)
Abortion:
(See Chap. 90 for protocol)
Psyllium
Metamucil
Dog: 13 tbsp/d (added to food)
Cat: 13 tsp/d (added to food)
Pyrantel pamoate
Nemex, Strongid
Dog: <2.5 kg: 10mg/kg PO >2.5 kg: 5mg/kg PO
Cat: 20mg/kg PO
Pyridostigmine bromide
Mestinon
Regonol
Antimyasthenic: 0.020.04mg/kg q2h IV, or 0.5
3.0mg/kg
q812h PO
Antidote (curariform): 0.150.3mg/kg IM, IV

Pyrimethamine
Daraprim
Dog: 1mg/kg q24h PO for 1428 days (5 days for
Neosporum caninum)
Cat: 0.51.0 mg/kg q24h PO for 1428 days
Quinacrine hydrochloride
Atabrine hydrochloride
Dog: 6.6 mg/kg q12h PO for 5 days
Cat: 11mg/kg q24h PO for 5 days
Quinidine gluconate
Quinaglute
Duraquin
Dog: 620mg/kg q6h IM; 620mg/kg q68h PO
(of base)
(324 mg quinidine gluconate = 202 mg quinidine
base)
Quinidine polygalacturonate
Cardioquin
Dog: 620mg/kg q6h PO (of base)
(275 mg quinidine polygalacturonate = 167 mg
quinidine
base)
Quinidine sulfate
Clin-Quin
Quinora
Dog: 620mg/kg q68h PO (of base)
(300 mg quinidine sulfate = 250 mg quinidine
base)
Ranitidine
Zantac
Dog: 2mg/kg q812h IV, PO
Cat: 2.5 mg/kg q12h IV; 3.5mg/kg q12h PO
Retinoids
See Isotretinoin; Retinol; Etretinate
Retinol
Aquasol-A
625800IU/kg q24h PO
Riboflavin (vitamin B2)
Dog: 1020mg/d PO
Cat: 510mg/d PO
Rifampin
Rifadin
1020mg/kg q24h PO
Ringers solution
4050ml/kg/d IV, SC, IP for maintenance
requirements
Salicylate
See Acetylsalicylic acid (aspirin)

Selegiline
See Deprenyl (Anipryl)
Senna
Senokot
Cat: 5ml/cat q24h (syrup); 1/2 tsp/cat q24h with
food
(granules)
SMS 201-995
Octreotide
1020mg q812h SC
Appendix 1957
Sodium bicarbonate (NaHCO3)
Acidosis: 0.51.0 mEq/kg IV, monitor blood
gases
(8.5% solution = 1 mEq/ml of NaHCO3)
Renal failure: 10 mg/kg q812h PO (adjust as
necessary)
Alkalinization of urine: 50 mg/kg q812h PO (1
tsp is
approximately 2 g)
Sodium chloride (0.9%)
4050ml/kg/d IV, SC, IP
Sodium chloride 7% (hypertonic saline)
28ml/kg/ IV for shock therapy
Sodium iodide (20%)
2040mg/kg q812h PO
Sodium nitroprusside
See Nitroprusside sodium
Sodium thiomalate
See Gold sodium thiomalate
Sotalol
Betapace
Dog: 13.5mg/kg q12h PO
Cat: 1/8 of 80 mg tab q12h PO
Spironolactone
Aldactone
12mg/kg q12h PO
Stanozolol
Winstrol-V
Dog: 14mg/dog q12h PO; 2550mg/dog/wk IM
Cat: 1mg/cat q12h PO; 25mg/cat/wk IM
Streptozotocin
(See Chapter 35 for administration protocol)
Sucralfate
Carafate
Dog: 0.51.0 g/dog q812h PO
Cat: 0.25 g/cat q812h PO
Sufentanil

Sufenta
2mg/kg IV, up to a maximum dose of 5mg/kg
(premedicate
with acepromazine)
Sulfadiazine
100mg/kg IV, PO (loading dose), followed by
50mg/kg
q12h IV, PO (see also Trimethoprim)
Sulfadimethoxine
Albon, Bactrovet
55mg/kg PO (loading dose), followed by
27.5mg/kg q12h
PO (see also Primor)
Sulfaguanidine
100200mg/kg q8h PO for 5 days
Sulfamethazine
100mg/kg PO (loading dose), followed by
50mg/kg q12h
PO
Sulfamethoxazole
Gantanol
100mg/kg PO (loading dose), followed by
50mg/kg q12h
PO
Sulfamethoxazole plus trimethoprim
Bactrim
Septra
See Trimethoprim plus sulfadiazine
Sulfasalazine (Sulfapyridine plus mesalamine)
Azulfidine (U.S.)
Salazopyrin (Canada)
Dog: 1030mg/kg q812h PO
Cat: 1020mg/kg q1224h PO
(See also Mesalamine, Olsalazine)
Sulfisoxazole
Gantrisin
50mg/kg q8h PO (urinary tract infections)
Tacrolimus
Prototopic (ointment)
Apply topically q24h
Taurine
Dog: 250500mg/dog q12h PO
Cat: 250mg/cat q12h PO
Tegaserod
Zelnorm
Dog: 0.050.1mg/kg q12h PO
Telezol
See Tiletamine plus zolazepam

Temaril-P (Trimeprazine plus prednisolone)

0.71.1 mg/kg (of trimeprazine) q1224h PO
Tepoxalin
Zubrin
Dog: 1020 mg/kg q24h PO then 10mg/kg q24h
PO
Terbinafine
Lamasil
Dog: 30 mg/kg q24h PO for 2128 days
Cat: 3040 mg/kg q24h PO for 2128 days
Terbutaline
Brethine, Bricanyl
Dog: 2.55.0mg/dog q8h SC, PO
Cat: 0.625mg/cat q12h SC, PO
Testosterone cypionate
Andro-Cyp
12mg/kg q24wk IM (see also
Methyltestosterone)
Testosterone propionate
Testex
Malogen
0.51.0 mg/kg 23 times/wk IM (see also
Methyltestosterone)
Tetanus toxoid (equine antitoxin)
100500U/kg (maximum 20,000U); IV slowly
over 510
minutes
Tetracycline
Panmycin
Achromycin
1522mg/kg q68h PO
4.411.0mg/kg q812h IV, IM
(See also Oxytetracycline, Doxycycline,
Minocycline)
Theophylline
Dog: 9mg/kg q68h PO
Cat: 4mg/kg q812h PO
(See also Aminophylline)
Theophylline (long-acting)
Theo-Dur
Slo-bid Gyrocaps
Dog: 20mg/kg q12h PO (Theo-Dur) 30mg/kg
q12h
PO (Slo-bid)
Cat: 25mg/kg q24h PO at night
Thiabendazole
Omnizole
1958 Appendix

Equizole
Dog: 50mg/kg q24h for 3 days, repeat 1 month
Cat (Strongyloides): 125mg/kg q24h for 3 days
Thiacetarsamine sodium
Caparsolate
2.2 mg/kg IV twice daily for 2 days
Thiamine (vitamin B1)
Dog: 10100mg/dog/d PO
Cat: 530mg/cat/d PO (up to a maximum dose
of
50mg/cat/d)
Thiomalate sodium
See Gold sodium thiomalate
Thiopental sodium
Pentothal
Dog: 610mg/kg IV (to effect)
Thiotepa
0.20.5mg/m2 intracavitary or IV
Thyroid hormone
See Levothyroxine, Liothyronine
Thyrotropin (TSH)
Thytropar
Dog: collect baseline sample, followed by
0.1IU/kg IV
(maximum dose is 5 IU); collect post-TSH sample
at
6 hours
Cat: collect baseline sample, followed by
2.5IU/cat IM
and collect post-TSH sample at 812 hours
Ticarcillin
Ticar
3350mg/kg q46h IV, IM
Tiletamine plus zolazepam
Telezol
0.54.0mg/kg IV, 410mg/kg IM, SC
Tobramycin
Nebcin
2mg/kg q8hr IV, IM, SC
Tocainide
Tonocard
Dog: 1020mg/kg q8h PO
Toluene
267mg/kg PO (of Toluene), repeat in 24 weeks
Topiramate
210mg/kg q12h PO
Tramadol
Dog: 1mg/kg q12h PO

Triamcinolone
Vetalog
Aristocort
Anti-inflammatory: 0.51.0 mg/kg q1224h PO,
taper dose
to 0.51.0mg/kg q48h PO
Triamcinolone acetonide
Vetalog
0.10.2 mg/kg IM, SC, repeat in 710 days
Intralesional: 1.21.8 mg, or 1 mg for every cm
diameter of
tumor q2wk
Tribrissen: see Trimethoprim sulfadiazine
Trientine hydrochloride
Syprine
1015mg/kg q12h, PO (1 hr before meals, do
not give
concurrently with other medications).
Triflupromazine
Vesprin
0.10.3mg/kg IM, PO q812h
Tri-iodothyronine
See Liothyronine
Trimeprazine
Panectyl
0.5 mg/kg q12hr PO (also see Temaril-P)
Trimethobenzamide
Tigan, Trimazide
Dog: 3mg/kg q8h IM, PO
Cat: not recommended
Trimethoprim plus sulfadiazine
Tribrissen
15mg/kg q12hr IM, PO, or 30mg/kg q1224h SC,
PO
(for Toxoplasma: 30mg/kg q12h PO)
Tripelennamine
Pelamine
1mg/kg q12h PO
TSH (thyroid-stimulating hormone)
See Thyrotropin
Tylosin
Tylocine, Tylan
2040mg/kg q12h PO
Urofollitropin
Metrodin
Cat: 2mg/cat q24h IM
Ursodiol (ursodeoxycholate)
Actigall

1015mg/kg q24h PO
Valproic acid
Depakene
Dog: 60200mg/kg q8h PO; or 25105mg/kg
q24h
PO when administered with phenobarbital
Vancomycin
Vancocin
Dog: 15mg/kg q68h IV
Cat: 1215mg/kg q8h IV
Vasopressin (ADH)
Pitressin
Aqueous (20U/ml): 10U IV, IM (see also
Desmopressin
acetate)
Verapamil
Calan
Isoptin
Dog: 0.05mg/kg q1030 min IV (maximum
cumulative dose is 0.15 mg/kg); oral dose is not
established
Cat: 1.12.9mg/kg q8h PO
Vermiplex
See Toluene
Vinblastine
Velban
2mg/m2 q714d IV
Vincristine
Oncovin
Antitumor: 0.50.75mg/m2 q7d IV
Thrombocytopenia: 0.025mg/kg once/wk IV
Viokase (See Pancreatic enzyme)
Appendix 1959
Vitamin A (Retinoids)
See Isotretinoin (Accutane), Retinol (Aquasol A),
or
Etretinate (Tegison)
Vitamin B complex
Dog: 0.52.0 ml q24hr IV, IM, SC
Cat: 0.51.0 ml q24hr IV, IM, SC
Vitamin B1
See Thiamine
Vitamin B2
See Riboflavin
Vitamin B12
See Cyanocobalamin
Vitamin C
See Ascorbic acid

Vitamin D
See Dihydrotachysterol; Ergocalciferol
Vitamin E (Alpha tocopherol)
Aquasol E
100400IU q12h PO (or 400600IU q12h PO for
immune-mediated skin disease, hepatitis, and
copper-associated liver disease)
Vitamin K1
AquaMEPHYTON
Mephyton
Short-acting rodenticide toxicity: 1mg/kg/d SC,
PO for
1014 days; long-acting rodenticide toxicity: 3
5mg/kg/d
SC, PO for 34 weeks; birds: 2.55.0mg/kg q24h
Severe cholestatic liver disease: 1mg/kg q12hr
SC or IM
Warfarin
Dog: 0.10.2 mg/kg q24h PO (adjust dose by
monitoring clotting time)
Cat: 0.060.1 mg/kg (monitor clotting time)
Xylazine
Rompun
Dog: 0.30.8mg/kg IV, 0.5 1.5mg/kg IM, SC
Cat: 0.41.0mg/kg IV, 0.81.8mg/kg IM, SC
Yohimbine
Yobine
For xylazine reversal: 0.10.4mg/kg IV
Zinc
Liver copper chelation: 510mg/kg q12hr PO (1
2 hr
separate from meals)
Zidovudine (AZT)
Retrovir
Cat: 15 mg q12h to 20mg/kg q8h PO
Zolazepam
See Tiletamine plus zolazepam
Zonisamide
510mg/kg/d PO (divide bid or tid)