Almazan, Jan Aira E-PH (Type Text)

Preparation 11 (Cinnamon Water)
- amber prescription bottle

- White Label
Aromatic waters
- clear, aqueous solutions saturated with volatile oils or other
aromatic or volatile substances
- odors and tastes should be dependent on the volatile
substances from which they are prepared
- should be free from empyreumatic (smoke-like) and other
foreign odors
- generally used as flavored and perfumed vehicle
- the volatile substance should be of pharmacopoeial quality or
of best quality if finest flavor is desired in case of unofficial
preparation
Aromatic waters can be prepared by 2 Official processes
1. Distillation
- most satisfactory method
- slowest and most expensive
- eg. Strong Rose Water
>Cohobation
- the process of repeatedly using the distillate to distill with
fresh portions of flowers/plant materials to minimize loss of
water soluble components
Eg. Orange/ Rose flowers
2. Solution
a. Direct Solution Method
Procedure:
- repeatedly shaking 2g or 2mL of the volatile substance with
1000 mL if purified water
- 12 hours set aside
- filtered with wetted filter paper
- made to volume by adding purified water through filter paper
>more convenient than distillation in terms of time and
equipment
>Do not agitate when drawing off aromatic water if the excess
volatile oil is allowed to remain.
b. Alternate Solution Method
Procedure:
- incorporating the volatile oil with 15g of talc or sufficient
amount of siliceous earth or pulped filter paper
- Add 1000mL of purified water
- mixture is agitated for 10 minutes
- water is then filtered (just add water when kulang)
Liquid Preparation:
1. 1 Phase system
- 1 homgenous layer (aromatic water, solution, elixir, syrup,
spirit)
2. 2 Phase system
- 2 layers; Thixotrophy (2 layers: standing :: 1 layer:shaking)
- GELOMAMI (Gel, Emulsion, Lotion, Magma, Mixture,
Suspension)
3. Extractives
- Galenical Products
> Tincture (Iodine tincture)
> Fluid extract
> Extract
4. Sterile Products
Note:
> Choosing a container
- Viscosity of Preparation
+ very viscous wide
+ less narrow
- light sensitivity
+ Very Amber
+ Not Flint
> Shake vigorously because oil and water are immiscible
> Small globules saturated solution
> Oil is denser than water
> Moistened Filter paper> so oil wont join the filtrate
Preparation 12 (Concentrated Peppermint Water)
- amber prescription bottle
- white label
- alternate solution method
Note:
> Aromatic water - no preservative (should be freshly
prepared)
Preparation 13 (Calcium Hydroxide Topical Solution)
- flint narrow bottle
- red label
Solutions
- liquid preparations that contain one or more chemical
substances dissolved in a suitable solvent or mixture of
mutually miscible solvents
- homogenous mixture of 2 or more substances
- should note the solubility and stability of each solute with
regard to the solvent or solvent system
Relative Terms of Solubility
Descriptive Term
Very Soluble
Freely Soluble
Soluble
Sparingly Soluble
Slightly Soluble
Very slightly soluble
Practically insoluble or
insoluble
Parts of Solvent Required

for 1 Part of solute
<1
1-10
10-30
30-100
100-1000
1000-10,000
>10,000
Methods of preparing solutions:
Almazan, Jan Aira E-PH[Type text]
Page 1
1. Simple Solution
- prepared by dissolving the solute in a suitable solvent
- eg. NaCl solution, Strong Iodine soln, Ca(OH)2
2. Solution by Chemical Reaction
- prepared by reacting two or more solute with each other in a
suitable solvent
- eg. Aluminum subacetatesoln, Magnesium citrate soln,
Sulfurated Lime soln
3. Solution by Distillation
- for volatile oil
4. Solution by extraction
- dug or pharmaceutical necessities of vegetable or animal
origin
- also called extractives
Different methods of extraction
a. Maceration submerging the solute
b. Percolation submerging with percolator
c. Digestion with the aid of gentle heat
d. Infusion blanching; addition of hot water
e. Decoction boiling for 15 minutes
In each 100 mL
- 4.5-5.5 g of iodine
- 9.5-10.5 g of potassium iodide
>1g of iodine dissolves in 2950mL
>solutions of iodides dissolve in large quantities of iodine
>Strong Iodine solution is a solution of polyiodides in excess
iodide
Procedure:
1. Dissolve KI in H2O
2. Add I2 to KI solution
- weigh with glass / porcelain
- very volatile (very difficult to remove)
- very reactive to meal
3. q.s. ad H2O
Preparation 15 (Magnesium Citrate Oral Solution)
Magnesium citrate OS
- colorless- slightly yellow clear effervescent liquid
- have sweet, acidulous taste, and lemon flavor
- excellent medium for the growth of molds
- and any mold spores present during the manufacture of the
solution must be killed if the preparation is to remain stable
Calcium Hydroxide very soluble in cold water

CaO ------------------>Ca(OH)2 ------------------> CaCO3
Slaking (5 min)
CO2
(white ppt)
Insoluble in water
Prevention of CaCO3
- cover it properly
CaO> H2O > Cold Water
*no shaking just mix
Preparation 14 (Strong Iodine Solution)
- amber narrow bottle
- red label
Almazan, Jan Aira E-PH[Type text]
Page 2
Procedure:
1.Dissolve citric acid in Hot H2O
2. Dissolve MgCO3 in 12 mL H2O
3. Mix 1 and 2
4. Add syrup then boil, then let it stand
5. Mortar; Triturate talc +lemon (flavoring agent). Triturate
6. Add 5 & 4
7. Filter while Hot > sterile container
8. Collect filtrate: qs ad water (60mL) purified
water/ordinary H2O stopper (cotton)
9. Attach the label
10. add Potassium Carbonate (KHCO3), submit and lay on its
side

Almazan, Jan Aira E-PH (Type Text)

Uploaded by

Copyright:

Available Formats

Almazan, Jan Aira E-PH (Type Text)

Uploaded by

Document Information

Original Description:

Original Title

Copyright

Available Formats

Share this document

Share or Embed Document

Sharing Options

Did you find this document useful?

Is this content inappropriate?

Copyright:

Available Formats

Almazan, Jan Aira E-PH (Type Text)

Uploaded by

Copyright:

Available Formats

Preparation 11 (Cinnamon Water)

- amber prescription bottle

Parts of Solvent Required

Methods of preparing solutions:

Almazan, Jan Aira E-PH[Type text]

Calcium Hydroxide very soluble in cold water

Almazan, Jan Aira E-PH[Type text]

You might also like