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Application of Acupuncture Therapy in Type 2 Diabetes Mellitus Patients

This study evaluated the effectiveness of acupuncture therapy in 20 patients with type 2 diabetes over 3 months. Key parameters such as fasting plasma glucose, HbA1c, lipid profiles, and body mass index were measured at baseline and during treatment. Acupuncture was administered to specific points daily for 10 days, followed by a 10 day rest, for a total of 3 months. The results suggested that acupuncture therapy significantly decreased several parameters and may be an effective complementary treatment for improving glycemic control and reducing diabetes complications in Indian patients.

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88 views4 pages

Application of Acupuncture Therapy in Type 2 Diabetes Mellitus Patients

This study evaluated the effectiveness of acupuncture therapy in 20 patients with type 2 diabetes over 3 months. Key parameters such as fasting plasma glucose, HbA1c, lipid profiles, and body mass index were measured at baseline and during treatment. Acupuncture was administered to specific points daily for 10 days, followed by a 10 day rest, for a total of 3 months. The results suggested that acupuncture therapy significantly decreased several parameters and may be an effective complementary treatment for improving glycemic control and reducing diabetes complications in Indian patients.

Uploaded by

ZulfaredaPutriI
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© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as RTF, PDF, TXT or read online on Scribd
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Vol-2, Issue-1, 2011 ISSN: 0976-7908

Ingle et al

PHARMA SCIENCE MONITOR


AN INTERNATIONAL JOURNAL OF PHARMACEUTICAL
SCIENCES

APPLICATION OF ACUPUNCTURE THERAPY IN TYPE


2
DIABETES MELLITUS PATIENTS
1

P. V. Ingle *, N. R. Samdani , P. H. Patil , M. S. Pardeshi , S. J. Surana

Department of Clinical Pharmacy, R. C. Patel Institute of Pharmaceutical Education & Research, Shirpur425405, Dist: Dhule, Maharashtra, India.
2
Smt. B.N.B. Swaminarayan Pharmacy College, Vapi, Pardi, Valsad, Gujarat, India.
3
Indira Gandhi Memorial Hospital, Shirpur-425405, Dist: Dhule, Maharashtra, India.

ABSTRACT
This study was design to observe the effectiveness of acupuncture therapy in type 2
diabetes mellitus patients. In this study 20 patients were selected for follow up on the
basis of inclusion & exclusion criteria. The main acupoints use were pishu (BL 20),
shenshu (BL 23), zusanli (ST 36), sanyinjiao (SP 6), hegu (LI 4), jianjing (GB21), quchi
(LI 11), waiguan (TW5), jiexi (St.41), taibai (Sp.3), taichong (Liv3), dazhui (Du14). All
the patients were punctured by using acupuncture needle with electric stimulation (Accu
Stimulator Apparatus), by DD wave, and the needles were retained for 20-30 minutes.
The treatment was given for 3 months time period. The parameter evaluated were fasting
plasma glucose, postprandial plasma glucose, glycosylated hemoglobin (HbA1c), lipid
profile and body mass index (BMI). At the end of study period it was observed that
acupuncture having overall good impact in most of the parameters. A significant
decreased were observed in patients after acupuncture therapy. This study was suggesting
that acupuncture therapy was effective in improving glycemic control, reducing HbA1c,
lipid profile and may helpful for reducing the complications in Indian patients with type 2
diabetes mellitus.
KEY WORDS: Diabetes Mellitus, acupuncture, glycosylated hemoglobin, lipid
profile, body mass index
INTRODUCTION
Diabetes mellitus is a group of metabolic disorders characterized by
hyperglycemia and abnormalities in carbohydrate, fat, and protein metabolism. Type 2
diabetes mellitus is chronic & progressive disorder characterized by impaired insulin
[1]

secretion and insulin resistance in the liver, adipose tissue & skeletal muscle . It is the
[2]

fourth leading cause of death in most developed countries . According to the World
Health Organisation estimates, India had 32 million diabetic subjects in the year 2000 and
www.pharmasm.com 18

Vol-2, Issue-1, 2011 ISSN: 0976-7908


[10]
resistance .
this number would increase to 80 million
by the year 2030

[3,4]

. The International

Ingle et al

So we design this study to assess the


role of acupuncture therapy in type 2

diabetes patients in concerned with the


Diabetes Federation (IDF) also reported
glycemic & lipid control.
that the total number of diabetic subjects in
India is 41 million in 2006 and that thisMATERIALS AND METHODS
would rise to 70 million by the yearStudy Design
[5]

2025 . It is quite evident from the above

The study protocol of this present

observations that diabetes has become astudy was approved by Institutional Human
major
health
problem
in
India.Ethical Committee of R. C. Patel Institute
Management of type 2 diabetes oftenof Pharmaceutical Education & Research,
necessitates changes in the patientsShirpur. The informed consent was taken
[6]

lifestyle . Management of type 2 includes from each patient before enrolling in the
diet, exercise and counseling regardingstudy at the hospital site. In an open label
[7]
complementary and alternative medicine study, we assess the effects of acupuncture

such as acupuncture, massage, hot tubtherapy in type 2 diabetes patients with a


therapy, biofeedback, yoga, herbalfollow up of up to 3 months. Men and
remedies also play important role inWomen were eligible to participate if they
[8]

reducing blood glucose level .

had uncontrolled type 2 diabetes, patients

Acupuncture is the practice ofwith HbA c 7 % and fasting plasma


1
inserting very fine needles into the skin to
glucose > 140 mg/dl.
stimulate specific anatomic points in the
Additional
exclusion
criteria
[9]
body for therapeutic purposes . Theincluded were a clinically relevant medical
probable

mechanism

by

which

acupuncture act in diabetes includes lower


blood glucose content, lower the release of
pancreatic glucagons, attenuate symptoms

and psychological condition, pregnant and


lactating women, alcoholic patient, history
of bleeding (G.I bleeding), chronic diabetes

andmellitus, patient who had known


polyuria), prevent slowing of motor nervehypersensitivity to oral hypoglycemic
conduction, improve microcirculation,agents, those who are on chronic
such

as

(polyphagia,

polydipsia

myocardial contractility, enhance bloodmedication


outflow and regulate vascular peripheral
www.pharmasm.com 19

Vol-2, Issue-1, 2011 ISSN: 0976-7908


Ingle et al
2. Clinical Investigation
All the laboratory investigation such
known to affect glucose metabolismas fasting and post prandial plasma
(Systemic or inhaled corticosteroid), renal
glucose level, HbA1c, and Lipid profile
disease or renal dysfunction, renal
(serum cholesterol, serum triglyceride, HDL
transplant, congestive heart failure, hepatic
Cholesterol, LDL Cholesterol)
insufficiency. Based on this inclusion anddetermination was done at the baseline.
exclusion criteria a total of 20 patients Body mass index (BMI) was calculated
were included in the study and takenbased on the height and weight of the
follow up during the treatment.

patients; because obesity is one of the major

There were 20 cases in this studyrisk factor in diabetes.


After taking the entire baseline

out of which 13 males and 07 female, the

average age was 52 1.6 years old. The readings of the various parameters, selected
average duration of disease was 7.7 1.4acupoints were use constantly for patients
years. The 14 patients found to have a those enrolled in the study. All the patients
family history of a diabetes mellitus and 6 were punctured by using acupuncture
patients with negative family history.

needle

after

arrival

of

the

needling

Treatment

sensation, the above acupoints were added

1. Acupoints

with electric stimulation (Accu Stimulator

After selecting the patients for thisApparatus), by DD wave, the intensity of


present study we have used the acupoints stimulation within the patient's tolerance,
like : Pishu (BL 20), Shenshu (BL 23), and the needles were retained for 20-30
Zusanli (ST 36), Sanyinjiao (SP 6), Hegu minutes. The treatment was given every day
(LI 4), Jianjing (GB21), Quchi (LI 11), for 10 days as one course of the treatments
Waiguan (TW5), Jiexi (St.41), Taibaiand after rest for 10 days; the second course
(Sp.3), Taichong (Liv3), Dazhui (Du14).of the treatment was started again. The
The acupoints used in this study wasentire

selected

selected based on various scientific studiesacupuncture

patient

therapy

for

undergone
3

months.

of acupuncture therapy in diabetes mellitusGenerally, the therapeutic effect could


and its complication.

appear after 1-2 courses of the treatments.


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