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Pathway DBD

Virus dengue infection causes a virus-antibody complex that depresses bone marrow function and activates the complement system, leading to bleeding and low platelet count. Increased permeability of membranes results in plasma leakage, hypovolemia, and hypotension. This causes metabolic acidosis.

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awliya
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100% found this document useful (1 vote)
516 views

Pathway DBD

Virus dengue infection causes a virus-antibody complex that depresses bone marrow function and activates the complement system, leading to bleeding and low platelet count. Increased permeability of membranes results in plasma leakage, hypovolemia, and hypotension. This causes metabolic acidosis.

Uploaded by

awliya
Copyright
© © All Rights Reserved
Available Formats
Download as DOC, PDF, TXT or read online on Scribd
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PATHWAY DBD

Infeksi virus dengue

Kompleks virus- antibody


depresi sumsum tulang

Aktivasi komplemen
perdarahan, trombositopenia

Antihistamin dilepaskan
PK Perdarahan

Permeabilitas membran meningkat

Kebocoran plasma

Hipovolemi

Renjatan hipovolemi, hipotensi

Asidosis metabolik

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