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    SOP Results - Alloxan Induced Mice

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    edgar_chieyahoocom
    The study tested the effects of Ampalaya Plus and Glipizide on blood glucose levels in mice. Tables 1 and 2 show that both treatments lowered blood glucose at 30 minutes, 6 hours, 12 hours, and 24 hours after administration compared to pre-administration levels. Table 3 shows that Glipizide reduced blood glucose levels more than Ampalaya Plus or a distilled water control. Statistical analysis in Tables 4 and 5 indicate that while both treatments lowered glucose compared to the control, Glipizide had a greater hypoglycemic effect than Ampalaya Plus.

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    SOP Results - Alloxan Induced Mice

    Uploaded by

    edgar_chieyahoocom
    71 views4 pages
    The study tested the effects of Ampalaya Plus and Glipizide on blood glucose levels in mice. Tables 1 and 2 show that both treatments lowered blood glucose at 30 minutes, 6 hours, 12 hours, and 24 hours after administration compared to pre-administration levels. Table 3 shows that Glipizide reduced blood glucose levels more than Ampalaya Plus or a distilled water control. Statistical analysis in Tables 4 and 5 indicate that while both treatments lowered glucose compared to the control, Glipizide had a greater hypoglycemic effect than Ampalaya Plus.

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    amapalaya

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    SOP Results- Alloxan Induced Mice

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    The study tested the effects of Ampalaya Plus and Glipizide on blood glucose levels in mice. Tables 1 and 2 show that both treatments lowered blood glucose at 30 minutes, 6 hours, 12 hours, and 24 hours after administration compared to pre-administration levels. Table 3 shows that Glipizide reduced blood glucose levels more than Ampalaya Plus or a distilled water control. Statistical analysis in Tables 4 and 5 indicate that while both treatments lowered glucose compared to the control, Glipizide had a greater hypoglycemic effect than Ampalaya Plus.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    71 views4 pages

    SOP Results - Alloxan Induced Mice

    Uploaded by

    edgar_chieyahoocom
    The study tested the effects of Ampalaya Plus and Glipizide on blood glucose levels in mice. Tables 1 and 2 show that both treatments lowered blood glucose at 30 minutes, 6 hours, 12 hours, and 24 hours after administration compared to pre-administration levels. Table 3 shows that Glipizide reduced blood glucose levels more than Ampalaya Plus or a distilled water control. Statistical analysis in Tables 4 and 5 indicate that while both treatments lowered glucose compared to the control, Glipizide had a greater hypoglycemic effect than Ampalaya Plus.

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    Ampalaya Plus on Alloxan Induced-Mice

    Statement of the Problem:


    1. What is the level of blood glucose of mice before and after 30minutes, 6hours, 12 hours, and
    12hours of administration of the following treatment:
    a. Ampalaya Plus
    b. Glipizide (Minidiab)

    Table 1. Blood Glucose of mice before and after 30minutes, 6hours, 12 hours, and 12hours
    of administration of Ampalaya Plus

    The table above showed that the mean blood glucose level of mice due to administration
    of Ampalaya Plus were the following: the mean blood glucose level 30minutes before
    administration of Ampalaya Plus 225.2222; 30 minutes after administration of Ampalaya Plus
    was 184.000; after 6 hours was 127.4444; after 12 hours was 97.4444; and after and 12hours was
    95.00.

    Table 2. Blood Glucose of mice before and after 30minutes, 6hours, 12 hours, and 12hours
    of administration of Glipizide

    The table above showed that the mean blood glucose level of mice due to administration
    of Glipizide were the following: the mean blood glucose level 30minutes before administration
    of Glipizide was 227.2222; 30 minutes after administration of Glipizide was 184.000; after 6
    hours was 127.4444; after 12 hours was 97.4444; and after and 12hours was 95.00.

    2. Which between Ampalaya Plus and Glipizide treatment exhibits a significantly lower glycemic
    level?
    Table 3. The Mean Blood Glucose Level after of administration of Glipizide, Distilled
    Water, and Ampalaya Plus

    The table above showed that the mean blood glucose level of mice due to administration
    of Glipizide 125.9722; for distilled water was 193.75; and for Ampalaya Plus was 148.9167.
    2

    From these results; the researchers inferred that the treatment which exhibited a
    significantly lower glycemic level was Glipizide.

    3. Is there any significant difference on the hypoglycemic effect of Glipizide and Ampalaya Plus
    on Alloxan induced mice?
    Analysis of Variance (ANOVA) was used to determine if significant difference
    existed for blood glucose level between the control groups and the experimental groups.
    Significance difference existed if significance (sig) is less than 0.05.

    Table 4. Significant difference between the mean blood glucose level in mebendazoletreated, water-treated, and Ampalaya Plus- treated mice

    Results above showed that there is significant difference (sig=0.000) between the mean
    blood glucose level in Glipizide-treated, water-treated, and Ampalaya Plus-treated mice.
    Test was conducted further to see where the differences were between the different
    groups using Least Square Difference (LSD). Results for LSD were given below.

    Table 5. Table for Least Square Difference (LSD)

    The LSD table showed that there was significant differences for the mean blood glucose
    level between: experimental group which was Ampalaya Plus-treated and positive control group
    which was Glipizide- treated (sig=0.019); experimental group and negative control group
    (sig=0.000).
    This significant difference between experimental group and the control groups ( positive
    and negative) showed that using Glipizide it will reduce significantly the blood glucose level of
    mice compared to using Ampalaya Plus or distilled water.

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