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JNTU Old Question Papers 2007

This document contains 4 sets of questions for a Bioinformatics exam. Each set contains 8 questions related to topics in Bioinformatics. The questions cover topics such as the definition and scope of Bioinformatics, sequence alignment algorithms like BLAST and Smith-Waterman, multiple sequence alignment, protein structure classification databases like CATH, phylogenetic tree construction methods like UPGMA, genome structure of prokaryotes and eukaryotes, gene prediction, and computer skills for Bioinformaticians. Students are instructed to answer any 5 questions out of the 8 in each set.

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578 views4 pages

JNTU Old Question Papers 2007

This document contains 4 sets of questions for a Bioinformatics exam. Each set contains 8 questions related to topics in Bioinformatics. The questions cover topics such as the definition and scope of Bioinformatics, sequence alignment algorithms like BLAST and Smith-Waterman, multiple sequence alignment, protein structure classification databases like CATH, phylogenetic tree construction methods like UPGMA, genome structure of prokaryotes and eukaryotes, gene prediction, and computer skills for Bioinformaticians. Students are instructed to answer any 5 questions out of the 8 in each set.

Uploaded by

Srinivasa Rao G
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
You are on page 1/ 4

Code No: RR322303 Set No.

1
III B.Tech II Semester Supplimentary Examinations, Aug/Sep 2007
BIO-INFORMATICS
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆⋆⋆⋆⋆

1. What is Bioinformatics? Describe its scope in modern biology? [16]

2. Write short notes on:

(a) Gapped BLAST


(b) PSI-BLAST
(c) BLAST (2) [16]

3. What is multiple sequence alignment? Describe the applications of multiple se-


quence alignments? [16]

4. Describe the following:

(a) Structural classifications of proteins


(b) The CATH (Class, Architecture, Topology, Homology) databases [16]

5. Explain Database searching with Smith-waterman Dynamic programming method?


[16]

6. Describe about Phylogenetic tree construction by using UPGMA method? [16]

7. Define Genome? Outline the structure and composition of prokaryotic and Eukary-
otic genomes? [16]

8. Write short notes on:

(a) GRAIL II
(b) ORF [16]

⋆⋆⋆⋆⋆

1 of 1
Code No: RR322303 Set No. 2
III B.Tech II Semester Supplimentary Examinations, Aug/Sep 2007
BIO-INFORMATICS
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆⋆⋆⋆⋆

1. Describe the following:

(a) Uniform Resource Locator (URL)


(b) Role of Internet in Bioinformatics [16]

2. Write a note on Parametric sequence alignment? [16]

3. How to multiply Aligned sequences and assessing quality of alignment? [16]

4. Define Secondary databases? Give an overview of secondary databases? [16]

5. What is Block Substitution Matrices (BLOSUM)? Describe them in detail? [16]

6. Write short notes on:

(a) Star decomposition


(b) PHYLIP programs [16]

7. Define Genome? Outline the structure and composition of prokaryotic and Eukary-
otic genomes? [16]

8. Write an essay on gene Prediction in Eukaryotes? [16]

⋆⋆⋆⋆⋆

1 of 1
Code No: RR322303 Set No. 3
III B.Tech II Semester Supplimentary Examinations, Aug/Sep 2007
BIO-INFORMATICS
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆⋆⋆⋆⋆

1. What are the basic Computer skills required for Bioinformatician? Write elemen-
tary commands in Linux operating system? [16]

2. Explain about different BLAST programs in detail with a neat flow charts and how
are they useful? [16]

3. How to multiply Aligned sequences and assessing quality of alignment? [16]

4. Write short notes on:

(a) Tr-EMBL
(b) P-fam [16]

5. Name the Database search algorithm employed in alignment of sequences and ex-
plain in detail about any one of it? [16]

6. Discuss in detail about Character based methods in phylogenetic Analysis? [16]

7. Describe briefly about different types of Gene mapping? [16]

8. Write short notes on:

(a) GRAIL II
(b) ORF [16]

⋆⋆⋆⋆⋆

1 of 1
Code No: RR322303 Set No. 4
III B.Tech II Semester Supplimentary Examinations, Aug/Sep 2007
BIO-INFORMATICS
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆⋆⋆⋆⋆

1. Write short notes on the following:

(a) Domain and Domain name


(b) Modem
(c) Routers
(d) FQDN [16]

2. Describe the following:

(a) Importance of GAPs and GAP penalties in sequence alignment


(b) Edit distance of two strings
(c) Dot matrix Analysis [16]

3. What is a multiple alignment and why we do it? [16]

4. Write short notes on:

(a) PDB
(b) SCOP [16]

5. What is Block Substitution Matrices (BLOSUM)? Describe them in detail? [16]

6. Describe about Phylogenetic tree construction by using UPGMA method? [16]

7. Write short notes on:

(a) Computer tools for sequencing


(b) DNA fingerprinting [16]

8. Write short notes on:

(a) GRAIL II
(b) ORF [16]

⋆⋆⋆⋆⋆

1 of 1

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