Drug Study

Medication Metronidazole
Classification Antibacterial Antiprotozoal Amebicide
Action (THERAPEUTIC) Hinders growth of selected organisms including most anaerobic bacteria and protozoal (CHEMICAL) Direct acting trichomonacide and amebicide that works at both intestinal and extraintestinal sites.
Indications Amebic hepatic abscess Intestinal amebiasis Trichomoniasis Refractory trichomoniasis Bacterial infection cause by anaerobic microorganism Post-operative infection Bacterial vaginosis
Contraindications Patients hypersensitivity to drugs and other metronidazole derivatives Use cautiously in patients receiving hepatotoxic drugs and on patients with history of blood dysecrasia, retinal or visual field changes hepatic disease or alcoholism
Adverse effect CNS: Depression Drowsiness Fever Headache Fatigue Irritability CV: Edema Flushing Thrombophlebitis EENT: Eye tearing GI: Abdominal cramping Anorexia Constipation Nausea and vomiting Diarrhea GU: Darkened urine Dysuria Incontinence
Nursing considerations Give drug with meals to minimize GI distress Give it at least 1-2 hours after meals Tell patient not to use alcohol or drugs that contain alcohol during therapy and at least 48 hours therapy is completed Instruct patient in proper hygiene Urge patient to complete full course of therapy even if he feels better
Chlorampenico
Anti-infective
Exerts bacteriostatic activity by binding with SOS subunit of ribosomes and inhibiting protein synthesis
Serious infection when less potentially dangerous drugs are ineffective or contra indicated
Hypersensitivity to drug Sever renal or hepatic impairment Prophylaxis for bacterial infection Acute porphyria
CNS: Confusion Depression EENT: Optic neuritis Vision loss GI: Nausea and vomiting Diarrhea Dry mouth
Monitor patient for signs and symptoms of aplastic anemia; which may occur n weeks or months after therapy ends. Monitor CBC count closely
SKIN: Rash Itching Angioedema OTHERS: Fever anaphylaxis
Assess hepatic enzyme levels in patient with hepatic disease Monitor creatinine levels in patients with renal insufficiency
Generic name : Ampicillin Brand Name : Rimacilin
Antiineffective
Destroys bacteria by inhibiting bacterial celwall synthesis during microbial multiplication
Hypersensitivity to penicillins, cephalosporins, imipenem or other beta lactamase inhibitors.
GI or urinary tract infection, including Neisseria gonorrheae infection in women
GI : >Nause and vomiting >Diarrhea >abdominal pain >Entercolitis >Gastritis >Stomatitis
>Watch out for sign and symptoms of hypersensitivit y reaction >Monitor for bleeding tendency or hemorrhage >Instruct patient to immediately report signs and symptoms of hypersesitivity reaction, such as rash, fever or chills >Watch out for sign and symptoms of hypersensitivit y reaction
Generic name : Ranitidine hydrochloride
Histamine receptor antagonist >Anti ulcer
Reduces gastric acid secretion and increase gastric mucus
>Active duodenal ulcer >Gastro
Hypersentivity to drugs.
GI : >Nausea and vomiting
Brand name : Zantac
drug
and bicarbonate production, creating a protective coating on gastric mucosa
esophageal reflux disease
>Diarrhea >constipation >Abdominal discomfort or pain
>Monitor for bleeding tendency or hemorrhage >Instruct patient to immediately report signs and symptoms of hypersesitivity reaction, such as rash, fever or chills
Name
Classification
Action
Indication
Contraindication
Adverse Reaction
Nursing Consideration
Generic Name: Tetracycline Hydrochloride
Anti-infectives
Brand Name: Achromycin
Unknown. Thought to exert bacteriostatic effect by binding to the 30s and possibly 50s ribosomal subunits of microorganisms, thus inhibiting protein synthesis. Also, alter cytoplasmic membrane of susceptibe microorganisms.
Infection caused by susceptible gram positive and negative bacteria, including entamoeba hystolytica.
Contraindication to patient hypersensitive to drug or other tetracyclines.
- Intracranial hypertension - Glossitis, nausea and vomiting - neutropenia
- Obtain specimen for culture and sensitivity test before giving first dose. - Dont expose to heat. - Drug isnt indicated for treatment of neurosyphilis.

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Drug Study

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Medication Metronidazole

Classification Antibacterial Antiprotozoal Amebicide

SKIN: Rash Itching Angioedema OTHERS: Fever anaphylaxis

Generic name : Ampicillin Brand Name : Rimacilin

Destroys bacteria by inhibiting bacterial celwall synthesis during microbial multiplication

Hypersensitivity to penicillins, cephalosporins, imipenem or other beta lactamase inhibitors.

GI or urinary tract infection, including Neisseria gonorrheae infection in women

GI : >Nause and vomiting >Diarrhea >abdominal pain >Entercolitis >Gastritis >Stomatitis

Generic name : Ranitidine hydrochloride

Histamine receptor antagonist >Anti ulcer

Reduces gastric acid secretion and increase gastric mucus

>Active duodenal ulcer >Gastro

GI : >Nausea and vomiting

Brand name : Zantac

and bicarbonate production, creating a protective coating on gastric mucosa

esophageal reflux disease

>Diarrhea >constipation >Abdominal discomfort or pain

Generic Name: Tetracycline Hydrochloride

Brand Name: Achromycin

Contraindication to patient hypersensitive to drug or other tetracyclines.

- Intracranial hypertension - Glossitis, nausea and vomiting - neutropenia

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