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Mefenamic Acid

Mefenamic acid is an anti-inflammatory, analgesic, and antipyretic drug used to treat moderate pain for no more than one week and primary dysmenorrhea. It works by inhibiting prostaglandin synthesis. It should be used cautiously in patients with asthma, renal or liver dysfunction, peptic ulcer disease, gastrointestinal bleeding, hypertension, CHF, pregnancy or lactation. The recommended dosage is 500 mg orally every 6 hours as needed for pain, not to exceed one week, or 500 mg orally followed by 250 mg every 6 hours starting at the onset of menstruation for dysmenorrhea for up to 3 days. Adverse effects include headaches, dizziness, gastrointestinal issues,

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114 views1 page

Mefenamic Acid

Mefenamic acid is an anti-inflammatory, analgesic, and antipyretic drug used to treat moderate pain for no more than one week and primary dysmenorrhea. It works by inhibiting prostaglandin synthesis. It should be used cautiously in patients with asthma, renal or liver dysfunction, peptic ulcer disease, gastrointestinal bleeding, hypertension, CHF, pregnancy or lactation. The recommended dosage is 500 mg orally every 6 hours as needed for pain, not to exceed one week, or 500 mg orally followed by 250 mg every 6 hours starting at the onset of menstruation for dysmenorrhea for up to 3 days. Adverse effects include headaches, dizziness, gastrointestinal issues,

Uploaded by

Shedrann Johan
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© Attribution Non-Commercial (BY-NC)
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Generic Name: Mefenamic Acid Brand Name: APO-Mefenamic Acid PMS-MEFENAMIC MEFENEMIC ACID PONSTAN, PONSTEL Drug classification:

Anti inflammatory, Analgesic, Antipyretic activities related to inhibition of prostaglandin synthesis Mode of Action: anti-inflammatory, analgesic, and antipyretic activities related to inhibition of prostaglandin synthesis;exact mechanism of action are not known. Indications: relief of moderate pain when therapy will not exceed one week. Treatment of primary dysmenorrhea Contraindications: contraindicated with hypersensitivity with mefenamic acid Use cautiously with asthma, renal or liver dysfunction, peptic Ulcer disease, gastrointestinal bleeding, hypertension, CHF, pregnancy and lactation. Suggested dose: 500 mg PO q 6 hrs. Ordered dose: Capsule 250 mg; adults and patients 14 yr and above, initially, 500 mg PO followed by 250 mg q 6 hr as needed. Do not exceed one week of therapy. this is for acute pain. 5oomg PO then 250 mg q 6 hr starting with the onset of bleeding. Can be initiated at start of mense and should not necessary for two to three days. For primary dysmenorrheal. Patient below 14 are not given this meds. Adverse effects CNS: headache, dizziness, somnolence, insomnia, fatigue, tiredness, tinnitus, ophthalmic effects. Dermatologic: rash, prumitus, sweating,dry mucos membranes, stomatitis GI: dysuria, renal impairment Hematologic: bleeding, platelet inhibition in higher doses, neutropenia, eosinophilia, leucopenia, pancytonea, thrombocytopenia, agranalocytosis, granalucytopenia, aplastic anemia, decrease Hgb OR hCT, bone marrowdepression,menorrhagia. Respiratory: dyspnea, hemoptysis, pharyngitis, bronchospasm, rhinitis Nursing responsibilities: 1. Give drugs with food or milk to decrease gastrointestinal upset. 2. Give prescribed dosage of drug to prevent Overdose or under dose administering of drug may result to trauma and further injury to the patients health. 3. Rendered health teaching such as: patient instructed to: a. does not share medicine with other patient; b. report signs of allergies or any unusualities. c. discuss some adverse effect of drug 4. Stay at the patient bedside during drug intake to insure that the patient take the medicine, 5. Give exact dose of drug and administer drug in the appropriate route.

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