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Asthma Algorithm

The document provides guidelines for managing asthma in children through a stepwise treatment approach. It describes the preferred and alternative treatment options for children ages 0-4 and 5-11 at different steps. The treatment recommendations are based on various levels of evidence from clinical studies in children and adults.

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23 views1 page

Asthma Algorithm

The document provides guidelines for managing asthma in children through a stepwise treatment approach. It describes the preferred and alternative treatment options for children ages 0-4 and 5-11 at different steps. The treatment recommendations are based on various levels of evidence from clinical studies in children and adults.

Uploaded by

1bsbfan
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOCX, PDF, TXT or read online on Scribd
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Key: Alphabetical order is used when more than one treatment option is listed within either preferred or alternative

therapy. ICS, inhaled corticosteroid; LABA, inhaled long-acting beta2-agonist; SABA, inhaled short-acting beta2-agonist

Key: Alphabetical order is used when more than one treatment option is listed within either preferred or alternative therapy. ICS, inhaled corticosteroid; LABA, inhaled long-acting beta2-agonist; SABA, inhaled short-acting beta2-agonist

y y y

STEPWISE APPROACH FOR MANAGING ASTHMA IN CHILDREN 0-4 YEARS OF AGE The stepwise approach is meant to assist, not replace, the clinical decision making required to meet individual patient needs. If alternative treatment is used and response is inadequate, discontinue it and use the preferred treatment before stepping up. If clear benefit is not observed within 4 6 weeks and patient/family medication technique and adherence are satisfactory, consider adjusting therapy or alternative diagnosis. Studies on children 0 4 years of age are limited. Step 2 preferred therapy is based on Evidence A. All other recommendations are based on expert opinion and extrapolation from studies in older children.

y y

STEPWISE APPROACH FOR MANAGING ASTHMA IN CHILDREN 5-11 YEARS OF AGE Theophylline is a less desirable alternative due to the need to monitor serum concentration levels. Step 1 and step 2 medications are based on Evidence A. Step 3 ICS + adjunctive therapy and ICS are based on Evidence B for efficacy of each treatment and extrapolation from comparator trials in older children and adults comparator trials are not available for this age group; steps 4 6 are based on expert opinion and extrapolation from studies in older children and adults. Immunotherapy for steps 2 4 is based on Evidence B for house-dust mites, animal danders, and pollens; evidence is weak or lacking for molds and cockroaches. Evidence is strongest for immunotherapy with single allergens.

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