Anatomy and Structures
Anatomy and Structures
PHYSIOLOGY:
The lymphatic system has three primary functions. First of all, it returns excess interstitial fluid to the
blood. Of the fluid that leaves the capillary, about 90 percent is returned. The 10 percent that does not
return becomes part of the interstitial fluid that surrounds the tissue cells. Small protein molecules may
"leak" through the capillary wall and increase the osmotic pressure of the interstitial fluid. This further
inhibits the return of fluid into the capillaries, and fluid tends to accumulate in the tissue spaces. If this
continues, blood volume and blood pressure decrease significantly and the volume of tissue fluid
increases, which results in edema (swelling). Lymph capillaries pick up the excess interstitial fluid and
proteins and return them to the venous blood. After the fluid enters the lymph capillaries, it is called
lymph.
The second function of the lymphatic system is the absorption of fats and fat-soluble vitamins from the
digestive system and the subsequent transport of these substances to the venous circulation. The
mucosa that lines the small intestine is covered with fingerlike projections called villi. There are blood
capillaries and special lymph capillaries, called lacteals, in the center of each villus. The blood capillaries
absorb most nutrients, but the fats and fat-soluble vitamins are absorbed by the lacteals. The lymph in the
lacteals has a milky appearance due to its high fat content and is called chyle.
The third and probably most well known function of the lymphatic system is defense against invading
microorganisms and disease. Lymph nodes and other lymphatic organs filter the lymph to remove
microorganisms and other foreign particles. Lymphatic organs contain lymphocytes that destroy invading
organisms.