This document summarizes information about the drug Depakene (valproic acid) including its generic and trade names, route of administration, dosage, drug class, mode of action, indications, contraindications, adverse reactions, drug interactions, and nursing considerations. Depakene is an anti-convulsant used to treat absence seizures. It works by increasing GABA levels in the brain. Nurses should monitor patients for side effects like asthenia and headache and educate patients about taking the drug as directed and avoiding alcohol and other CNS depressants.
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This document summarizes information about the drug Depakene (valproic acid) including its generic and trade names, route of administration, dosage, drug class, mode of action, indications, contraindications, adverse reactions, drug interactions, and nursing considerations. Depakene is an anti-convulsant used to treat absence seizures. It works by increasing GABA levels in the brain. Nurses should monitor patients for side effects like asthenia and headache and educate patients about taking the drug as directed and avoiding alcohol and other CNS depressants.
Generic Name: Valproic acid Trade Name: Depakene Available Stock: syrup 250mg/5ml Route of Administration: oral Dosage: 10-15mg/kg/day Drug Class Mode of Indications/ Adverse Drug Nursing Considerations Health Teachings Action Contraindic. Reactions Interactions Anti - Increase Indications: Asthenia, Alcohol - ↑CNS *to minimize GI irritation- *take with food or after convulsant GABA levels For treatment of headache, Depression intiate at lower dose, give meals to minimize GI In brain Simple or somnolence, Cimetidine - with food upset complex dizziness, ↑pharmacologic *to minimize CNS *take only as directed and Absence tremor, effects depression, give at do not stop abruptly seizures insomnia bedtime Mimic or Contra CNS: Penobarbital - *reduce starting dose in * do not drive until drug Enhance -indications: Hyperammo- ↑effects and geriatric patients effects are realized. Inhibitory Liver disease or nemic toxicity of * avoid alcolhol, CNS effect of Dysfunction encephalopathy phenobarbital depressants GABA Urea cycle *report for periodic cbc, disorders serume glucose, and liver Lactationa function tests Acute *do not take if pregnant pancreatitis Hematologic: hemorrhage Arthralgia Stevens Johnson syndrome Prepared by: AMR Morelos, MD