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Introduction of Clinical Biochemistry

The document discusses clinical biochemistry and the functions of clinical laboratories. Clinical laboratories support the diagnosis, monitoring, and screening of diseases by analyzing samples like blood, urine, and cerebrospinal fluid. They examine metabolites, enzymes, electrolytes, proteins, hormones, antigens, antibodies, coagulation factors, blood types, and drugs. Immunoassay methods have evolved over generations to more accurately detect substances in samples, from early radioimmunoassays to current techniques like ELISA, IRMA, and MEIA.

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Hazrati Ummi
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29 views32 pages

Introduction of Clinical Biochemistry

The document discusses clinical biochemistry and the functions of clinical laboratories. Clinical laboratories support the diagnosis, monitoring, and screening of diseases by analyzing samples like blood, urine, and cerebrospinal fluid. They examine metabolites, enzymes, electrolytes, proteins, hormones, antigens, antibodies, coagulation factors, blood types, and drugs. Immunoassay methods have evolved over generations to more accurately detect substances in samples, from early radioimmunoassays to current techniques like ELISA, IRMA, and MEIA.

Uploaded by

Hazrati Ummi
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPT, PDF, TXT or read online on Scribd
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Introduction of

Clinical Biochemistry

The Function of Clinical


Laboratory
1. Supporting the diagnosis of
2.
3.
4.
5.
6.
7.

disease
Monitoring the course of the
disease (prognosis)
Monitoring therapy
(effectiveness of treatment)
Screening of the diseases or risk
factors
Check up (prevention)
Epidemiological studies
Supporting health research

The Clinical Laboratory


1. Chemistry
2. Hematology
3. Urine

analysis
4. Microbiology
5. Imunoserology
6. Therapeutic
drug
monitoring

Samples
1. Blood / serum/
2.
3.
4.
5.

plasma
Urine
Faeces
Cerebrospinal
fluid
Transudate /
exudate

Examination in the Clinical


Laboratory
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.

Metabolyte
Enzym
Electrolyte
Proteine
Hormone
AntigenBacteri/virus
Antibody
Allergen
Koagulation factors
ABO/Rhesus
HLA
Drugs
Trace elemen

Immuno-chemistry Methodes
Generation 1

(1980 early))
Generation 2
(1980 medio

Generation 3
(1990)

: RIA

: ELISA
EMIT
FPIA
Nephelometry
: IRMA
ELISA
Streptavidin-biotin
MEIA
CEDIA
ICMA

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