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    Iron It Out

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    The document discusses the connection between hemochromatosis and the Black Plague. It explains that having more iron in the body makes a person more vulnerable to the plague, as bacteria need iron to live and are able to take iron from white blood cells called microphages. During the plague, microphages from people with hemochromatosis did not have excess iron, leaving the bacteria weak and allowing the microphages to better kill the plague bacteria. This provided an evolutionary advantage during the pandemic.

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    Iron It Out

    Uploaded by

    api-296981910
    144 views8 pages
    The document discusses the connection between hemochromatosis and the Black Plague. It explains that having more iron in the body makes a person more vulnerable to the plague, as bacteria need iron to live and are able to take iron from white blood cells called microphages. During the plague, microphages from people with hemochromatosis did not have excess iron, leaving the bacteria weak and allowing the microphages to better kill the plague bacteria. This provided an evolutionary advantage during the pandemic.

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    The document discusses the connection between hemochromatosis and the Black Plague. It explains that having more iron in the body makes a person more vulnerable to the plague, as bacteria need iron to live and are able to take iron from white blood cells called microphages. During the plague, microphages from people with hemochromatosis did not have excess iron, leaving the bacteria weak and allowing the microphages to better kill the plague bacteria. This provided an evolutionary advantage during the pandemic.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    144 views8 pages

    Iron It Out

    Uploaded by

    api-296981910
    The document discusses the connection between hemochromatosis and the Black Plague. It explains that having more iron in the body makes a person more vulnerable to the plague, as bacteria need iron to live and are able to take iron from white blood cells called microphages. During the plague, microphages from people with hemochromatosis did not have excess iron, leaving the bacteria weak and allowing the microphages to better kill the plague bacteria. This provided an evolutionary advantage during the pandemic.

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    © All Rights Reserved
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    Download as pptx, pdf, or txt
    of 8

    THE BLACK PLAGUE

    AND
    HEMOCHROMATOSIS
    By Jared

    Why would you take a pill that was


    guaranteed to kill you in forty years?

    SURVIVAL OF THE SICKEST


    BY SHARON MOALEM
    PAGE 14
    PARAGRAPH 1

    The Bubonic Plague

    Started in 1347
    Killed over 25 million
    (1/3 of Europe)
    Highly contagious
    Painfully Swells Lymph
    nodes

    Picture from "Black Death." Black Death. N.p., n.d. Web. 24


    Sept. 2015.
    <https://faculty.history.wisc.edu/sommerville/123/123%20161%
    20Black%20Death.htm>.

    Iron and the Plague

    The more iron in your body the more


    vulnerable you are to the plague.

    Microphages

    White Blood Cells


    Find, Surround,
    Subdue or Kill
    Bacteria
    Brings bacteria
    back to the lymph
    nodes
    Have iron (like all
    other cells)

    Picture from
    http://medicalxpress.com/news/2015-04-monocytes-macrophages-human-cancergrowth.html

    Iron and the Plague

    The more iron in your body the more


    vulnerable you are to the plague.
    Iron is needed for bacteria to live.
    Bacteria take iron from the microphages
    Bacteria grow stronger and over take our
    immune system due to iron from the
    microphages

    Hemochromatosis

    All cells have excess iron except one:


    microphages.
    Iron depriving microphages leave the
    bacteria weak and are better adapted to
    kill off bacteria such as in the black
    death.

    Why would you take a pill that was


    guaranteed to kill you in forty years?

    Because it will save you


    tomorrow.
    SURVIVAL OF THE SICKEST
    BY SHARON MOALEM
    PAGE 14
    PARAGRAPH 1

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