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Accepted Name: Arogenate Dehydratase Reaction:: Click Here

Arogenate dehydratase is an enzyme that catalyzes the reaction of L-arogenate to form L-phenylalanine, water, and carbon dioxide. It also acts on prephenate and D-prephenyllactate. Arogenate dehydratase is also known as carboxycyclohexadienyl dehydratase or L-arogenate hydro-lyase (decarboxylating; L-phenylalanine-forming).

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68 views1 page

Accepted Name: Arogenate Dehydratase Reaction:: Click Here

Arogenate dehydratase is an enzyme that catalyzes the reaction of L-arogenate to form L-phenylalanine, water, and carbon dioxide. It also acts on prephenate and D-prephenyllactate. Arogenate dehydratase is also known as carboxycyclohexadienyl dehydratase or L-arogenate hydro-lyase (decarboxylating; L-phenylalanine-forming).

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Iseng Iseng
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EC 4.2.1.

91
Accepted name: arogenate dehydratase
Reaction: L-arogenate = L-phenylalanine + H2O + CO2
For diagram click here.
Other name(s): carboxycyclohexadienyl dehydratase; L-arogenate hydro-lyase
(decarboxylating)
Systematic name: L-arogenate hydro-lyase (decarboxylating; L-phenylalanineforming)
Comments: Also acts on prephenate and D-prephenyllactate. cf. EC 4.2.1.51,
prephenate dehydratase.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS
registry number: 76600-70-9
References:
1. Fischer, R. and Jensen, R. Arogenate dehydratase. Methods Enzymol. 142 (1987)
495-502. [PMID: 3600377]
2. Zamir, L.O., Tiberio, R., Devor, K.A., Sauriol, F., Ahmad, S. and Jensen, R.A.
Structure of D-prephenyllactate. A carboxycyclohexadienyl metabolite
from Neurospora crassa. J. Biol. Chem. 263 (1988) 17284-17290. [PMID: 2972718]
3. Siehl, D.L. and Conn, E.E. Kinetic and regulatory properties of arogenate
dehydratase in seedlings of Sorghum bicolor (L.) Moench. Arch. Biochem.
Biophys. 260 (1988) 822-829. [PMID: 3124763]
[EC 4.2.1.91 created 1992, modified 2005]

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