Revised Matrix / Table of Specifications (TOS) for the Licensure Examination
(Finalized with PASMETH & PAMET on June 6, 2009)
SUBJECT & TOTAL WEIGHT
TOPIC & SUB-TOPIC
Clinical Chemistry (20%)
1
2
3
4
5
7
8
Hematology (20%)
1
2
Page 1 of 10
Revised Matrix / Table of Specifications (TOS) for the Licensure Examination
(Finalized with PASMETH & PAMET on June 6, 2009)
SUBJECT & TOTAL WEIGHT
TOPIC & SUB-TOPIC
Blood Banking,
Immunology and Serology
(20%)
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
Page 2 of 10
Revised Matrix / Table of Specifications (TOS) for the Licensure Examination
(Finalized with PASMETH & PAMET on June 6, 2009)
SUBJECT & TOTAL WEIGHT
TOPIC & SUB-TOPIC
Clinical Microscopy (10%)
1
2
3
4
5
6
Page 3 of 10
Revised Matrix / Table of Specifications (TOS) for the Licensure Examination
(Finalized with PASMETH & PAMET on June 6, 2009)
SUBJECT & TOTAL WEIGHT
TOPIC & SUB-TOPIC
Microbiology/ Parasitology
(20%)
1
2
3
4
5
8
Page 4 of 10
Revised Matrix / Table of Specifications (TOS) for the Licensure Examination
(Finalized with PASMETH & PAMET on June 6, 2009)
SUBJECT & TOTAL WEIGHT
TOPIC & SUB-TOPIC
Histopath, MT Laws,
Related Laws & Code of
Ethics (10%)
4
5
6
7
8
9
Page 5 of 10
PROFESSIONAL REGULATION COMMISSION
Board of Medical Technology
Revised Matrix / Table of Specifications (TOS) for the Licensure Examination
(Finalized with PASMETH & PAMET on June 6, 2009)
WEIGHT
(%)
TOPIC & SUB-TOPIC
Specimen collection
Instrumentation (Principles, Methods, Calibration, Others)
Reagent preparation and laboratory mathematics
Quality assurance
5%
5%
5%
10%
Metabolic Blood Tests (Principles, Procedures, Diseases/Disorders, Reference values)
50%
5.1. Water balance and electrolytes
5.2. NPN and other metabolic intermediaries and inorganic ions
5.3. Carbohydrates
5.4. Lipids and dysproteinemia
5.5. Specific proteins
5.6. Liver function tests
5.7. Clinical enzymology
Endocrinology and Toxicology (Principles, Procedures, Diseases/Disorders, Reference values)
6.1. Endocrinology
6.1.1. Thyroid Hormones
6.1.2. Sex Hormones
6.1.3. Other Hormones (Pituitary, Adrenal)
6.2. Toxicology & Therapeutic Drug Monitoring (TDM)
6.2.1. Substance of Abuse
8%
8%
6%
8%
6%
6%
8%
16%
4%
3%
3%
2%
6.2.2. Other poisons/toxic agents (Alcohol, Carbon monoxide, Mercury, Lead, Arsenic)
2%
6.2.3. TDM - Anticonvulsants and other drugs
2%
Blood gas analysis and other tests (Principles, Procedures, Diseases/ Disorders, Reference values)
4%
Laboratory safety
5%
Total
Blood collection, anticoagulants and others (including Safety)
Hematology tests and procedures
2.1. Routine
2.2. Automation
2.3. Special
Hematopoiesis, Diseases/Disorders and Reference values
3.1. Hematopoiesis (in general)
3.2. Erythropoiesis and RBCs
3.3. Leukopoiesis and WBCs
3.4. Thrombopoiesis and Platelets
Coagulation (Principles, Procedures, Diseases/Disorders and Reference values)
4.1. Hemostasis - Theories/Concepts, Mechanisms
4.2. Coagulation procedures/tests
4.3. Coagulation factors, diseases/disorders & reference values
Quality assurance
Page 6 of 10
100%
5%
30%
15%
10%
5%
40%
6%
12%
12%
10%
20%
2%
8%
10%
5%
PROFESSIONAL REGULATION COMMISSION
Board of Medical Technology
Revised Matrix / Table of Specifications (TOS) for the Licensure Examination
(Finalized with PASMETH & PAMET on June 6, 2009)
TOPIC & SUB-TOPIC
Total
WEIGHT
(%)
100%
Blood Banking (50%)
ABO and Rh Blood Group Systems
5%
Other Major Blood Group Systems: Kell, Duffy, Kidd, Lewis, MNSs, Lutheran, P, I
3%
Minor Blood Group Systems: Diego, Cartwright, Chido, XG, Scianna, Gerbich, Milton, Knops, Bg,
Indian, etc
Basic Genetics
Blood donor selection and processing
Blood preservation and banking
Component preparation
Transfusion therapy
Transfusion reactions
Transfusion-transmitted diseases
1%
2%
5%
5%
5%
2%
3%
3%
BB techniques and procedures : typing, compatibility testing, antibody detection and identification
8%
Hemolytic Disease of the Newborn (HDN) and Auto-immune Hemolytic Anemia
4%
Quality management (structure, set-up/ equipment, Laboratory Information System/LIS)
4%
Sub-Total
50%
Immunology/Serology (50%)
Historical background
2%
Natural (innate) immunity, including role of macrophages, monocytes and granulocytes
5%
Acquired immunity - humoral responses, immunogens, immunoglobulins, B cells
8%
Acquired immunity - cellular responses, T cells, cytokines and chemokines
Complement System
MHC, HLA and Transplantation
Immunologic tests for detection of antigens & antibodies - principles, procedures, interpretation of
results
20.1. Bacterial infections and STD
20.2. Viral infections, including Hepatitis and HIV
20.3. Fungal infections
20.4. Parasitic infections, including malaria
20.5. Autoimmune disorders
Tumor immunology (Tumor markers, Oncoproteins)
Hypersensitivity
Instrumentation and quality management
Sub-Total
5%
2%
3%
Page 7 of 10
16%
5%
5%
1%
2%
3%
3%
1%
5%
50%
PROFESSIONAL REGULATION COMMISSION
Board of Medical Technology
Revised Matrix / Table of Specifications (TOS) for the Licensure Examination
(Finalized with PASMETH & PAMET on June 6, 2009)
TOPIC & SUB-TOPIC
Total
Urine
1.1. Anatomy and physiology of the kidney
Formation of urine
1.2. Macroscopic examination
1.3. Chemical analyses
1.4. Microscopic examination
1.5. Pregnancy testing
1.6. Renal calculi
Feces
Other Body Fluids
3.1. CSF
3.2. Seminal Fluid
3.3. Amniotic Fluid
3.4. Gastric Fluid and Duodenal Content
3.5. Sputum and Bronchial Washings
3.6. Synovial Fluid
3.7 Peritoneal, Pleural, and Pericardial Fluids
Collection, preservation and handling of specimens
Microscope, automation, other instruments
Quality assurance and laboratory safety
WEIGHT
(%)
100%
53%
5%
10%
18%
15%
2%
3%
3%
21%
5%
5%
3%
2%
2%
2%
2%
10%
5%
8%
Total
Page 8 of 10
100%
PROFESSIONAL REGULATION COMMISSION
Board of Medical Technology
Revised Matrix / Table of Specifications (TOS) for the Licensure Examination
(Finalized with PASMETH & PAMET on June 6, 2009)
TOPIC & SUB-TOPIC
WEIGHT
(%)
Microbiology (70%)
Bacteriology
1.1. Collection, transport , processing and staining of specimens
1.2. Culture media
1.3. Bacteria (Aerobes)
1.3.1. Morphology and staining characteristics
1.3.2. Cultural characteristics
1.3.3. Work-up for identification: biochemical, differential and confirmatory tests
1.3.4. Serologic/molecular tests
1.3.5. Susceptibility tests
1.3.6. Bacteriologic examination of water, food, milk, and utensils
1.4. Bacteria (Anaerobes)
1.5. Mycobacteria
1.6. Other bacteria with unusual growth requirements (Spirochetes, Chlamydia, Mycoplasma,
Rickettsia)
Mycology
2.1. Collection, transport and examination of clinical specimens
2.2. Culture
Virology
3.1. General characteristics, transmission and diseases
3.2. Collection, transport and examination of clinical specimens
Equipment and instrumentation
4.1. Manual
4.2. Automated
Quality assurance and safety
5.1. Collection of specimen
5.2. Quality control
5.3. Safety - patient/staff
5.4. Safety - workplace/environment
Sub-Total
Parasitology (30%)
Parasites - life cycle, morphological characteristics,epidemiology, prevention and control, manner of
reporting, counting
6.1. Nematodes
6.2. Trematodes
6.3. Cestodes
6.4. Protozoa
6.5. Ectoparasites
Parasitologic Techniques
7.1. Routine
7.2. Concentration
7.3. Others
Quality assurance
Page 9 of 10
49%
5%
5%
5%
5%
14%
3%
4%
2%
2%
2%
2%
4%
2%
2%
4%
2%
2%
5%
3%
2%
8%
2%
2%
2%
2%
70%
21%
5%
5%
5%
5%
1%
5%
2%
2%
1%
4%
PROFESSIONAL REGULATION COMMISSION
Board of Medical Technology
Revised Matrix / Table of Specifications (TOS) for the Licensure Examination
(Finalized with PASMETH & PAMET on June 6, 2009)
TOPIC & SUB-TOPIC
8.1. Collection and preservation of specimen
8.2. Quality control
WEIGHT
(%)
2%
2%
Sub-Total
30%
Total
100%
Histopathology (65%)
Histology and Pathology
1.1. Terminologies
1.2. Etiology of disease
1.3. Signs, symptoms and course of disease
1.4. Cellular and tissue changes
Histopathologic techniques and procedures
2.1. Preservation and handling of specimen
2.2. Tissue processing and procedures
2.2.1. Routine- Manual
2.2.2. Routine- Automation
2.2.3. Special - Frozen section, Microwave
2.3. Staining
2.3.1. Routine
2.3.2. Special (Immunohistochemistry)
Cytological techniques and procedures
3.1. Preservation and handling of specimen
3.2. Processing
3.2.1. Manual
3.2.2. Automation
3.3. Staining
Autopsy
4.1. Terminologies
4.2. Handling, processing and documentation
Quality assurance
10%
4%
2%
2%
2%
35%
10%
7%
5%
3%
5%
5%
8%
2%
2%
2%
2%
2%
1%
1%
Sub-Total
10%
65%
Sub-Total
10%
10%
10%
5%
35%
Total
100%
MT Laws, Related Laws and Code of Ethics (35%)
MT Laws
Laboratory Management
Related Laws
Code of Ethics including Bioethics
Page 10 of 10