Worksheet - Enzymes - Review
Worksheet - Enzymes - Review
Worksheet - Enzymes - Review
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Part A: Definitions: Define the following terms, IN YOUR OWN WORDS, IN AS FEW WORDS AS
CLARITY AND COMPLETENESS ALLOW.
metabolism
substrate
enzyme
active site
apoenzyme
coenzyme
metabolic pathway
activation energy
13. Label all missing parts on the graphs to the right. Highlight the energy of activation on both graphs.
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Progress of Reaction
Progress of Reaction
14. Which graph below best represents a graph of the Enzyme activity vs pH?
Part C: Thinking Questions - Answer on separate sheets of paper, in your OWN WORDS.
1. What advantages can you see in having complex metabolic pathways within body cells to produce various
substances, such as amino acids and ATP?
What gland produces the hormone thyroxin? What is the function of thyroxin in metabolism?
3. Explain, using a good example, how a metabolic pathway can be self-regulating (that is, how it can shut itself on
and off).
4. How does the Lock and Key theory of enzyme action differ from the Induced Fit theory? Use diagrams to help
your explanation.
5. Why do you think each enzyme has its own preferred pH at which it operates?
6. What is the effect of lowering the temperature on enzyme activity. How about raising the temperature? Draw a graph
to show these relationships.
7. Describe three factors that can lead to the denaturing of enzymes. How would denaturing an enzyme affect its
activity?
8. What happens to the rate of product formation if you continue to add to an enzyme-catalyzed reaction the following:
a) substrate b) enzyme c) an inhibitor d) Lead, mercury, or cadmium e) H+ ions f) OH= ions
9. Explain, using diagrams, how competitive inhibitors differ from non-competitive inhibitors in the way they act on
enzymes.
10. Discuss, using examples, the effects of reversible and non-reversible inhibitors on enzyme activity.
11. Explain the role of vitamins in metabolic reactions. List at least 2 examples.
12. Explain why a genetic defect that affects only one enzyme in a metabolic pathway can have serious consequences.
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