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    GENERIC NAME: Ranitidine BRAND NAME: Zantac CLASSIFICATION Therapeutic: Anti-Ulcer Agents

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    ehnna
    Ranitidine (brand name Zantac) is an anti-ulcer drug that works by inhibiting histamine at gastric parietal cells, reducing stomach acid production. It is used to treat conditions like heartburn and acid indigestion. Side effects may include dizziness, diarrhea, altered taste, and skin reactions. Cefuroxime (brand name Ceftin) is a cephalosporin antibiotic used to treat respiratory, skin, urinary, and bone infections. It works by inhibiting bacterial cell wall synthesis. Contraindications include penicillin allergy. Common adverse effects are nausea, vomiting, diarrhea, and changes in liver enzymes.

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    GENERIC NAME: Ranitidine BRAND NAME: Zantac CLASSIFICATION Therapeutic: Anti-Ulcer Agents

    Uploaded by

    ehnna
    9K views4 pages
    Ranitidine (brand name Zantac) is an anti-ulcer drug that works by inhibiting histamine at gastric parietal cells, reducing stomach acid production. It is used to treat conditions like heartburn and acid indigestion. Side effects may include dizziness, diarrhea, altered taste, and skin reactions. Cefuroxime (brand name Ceftin) is a cephalosporin antibiotic used to treat respiratory, skin, urinary, and bone infections. It works by inhibiting bacterial cell wall synthesis. Contraindications include penicillin allergy. Common adverse effects are nausea, vomiting, diarrhea, and changes in liver enzymes.

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    Ranitidine (brand name Zantac) is an anti-ulcer drug that works by inhibiting histamine at gastric parietal cells, reducing stomach acid production. It is used to treat conditions like heartburn and acid indigestion. Side effects may include dizziness, diarrhea, altered taste, and skin reactions. Cefuroxime (brand name Ceftin) is a cephalosporin antibiotic used to treat respiratory, skin, urinary, and bone infections. It works by inhibiting bacterial cell wall synthesis. Contraindications include penicillin allergy. Common adverse effects are nausea, vomiting, diarrhea, and changes in liver enzymes.

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    Download as doc, pdf, or txt
    9K views4 pages

    GENERIC NAME: Ranitidine BRAND NAME: Zantac CLASSIFICATION Therapeutic: Anti-Ulcer Agents

    Uploaded by

    ehnna
    Ranitidine (brand name Zantac) is an anti-ulcer drug that works by inhibiting histamine at gastric parietal cells, reducing stomach acid production. It is used to treat conditions like heartburn and acid indigestion. Side effects may include dizziness, diarrhea, altered taste, and skin reactions. Cefuroxime (brand name Ceftin) is a cephalosporin antibiotic used to treat respiratory, skin, urinary, and bone infections. It works by inhibiting bacterial cell wall synthesis. Contraindications include penicillin allergy. Common adverse effects are nausea, vomiting, diarrhea, and changes in liver enzymes.

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    GENERIC NAME: Ranitidine

    BRAND NAME: Zantac

    CLASSIFICATION
    Therapeutic:
    Anti-ulcer agents

    MECHANISM OF ACTION
    • Inhibits the action of histamine at the H2 receptor site
    located primarily in gastric parietal cells, resulting in
    inhibition of gastric acid secretion.

    • In addition, ranitidine bismuth citrate has some


    antibacterial action against H. pylori.

    INDICATION
    •Treatment and prevention of heartburn, acid indigestion,
    and sour stomach.

    CONTRA INDICATIONS
    Contraindicated in:

    •Hypersensitivity, Cross-sensitivity may occur; some oral


    liquids contain alcohol and should be avoided in patients
    with known intolerance.

    Use Cautiously in:

    • Renal impair- ment


    • Geriatric patients (more
    susceptible to adverse CNS reactions)
    • Pregnancy or Lactation

    SIDE EFFECTS/ ADVERSE EFFECTS


    • CNS:
    Confusion, dizziness, drowsiness, hallucinations,
    headache

    • CV:
    Arrhythmias

    • GI:
    Altered taste, black tongue, constipation, dark stools,
    diarrhea, drug-induced hepatitis, nausea

    • GU:
    Decreased sperm count, impotence

    • ENDO:
    Gynecomastia

    • HEMAT:
    Agranulocytosis, Aplastic Anemia, neutropenia,
    thrombocytopenia

    • LOCAL:
    Pain at IM site

    • MISC:
    Hypersensitivity reactions, vasculitis

    GENERIC NAME: Cefuroxime

    BRAND NAME: Ceftin


    CLASSIFICATION
    Mechanism of Action:

    Inhibits bacterial cell wall synthesis by binding to one or more of the penicillin-binding proteins
    (PBPs) which in turn inhibits the final transpeptidation step of peptidoglycan synthesis in
    bacterial cell walls, thus inhibiting cell wall biosynthesis. Bacteria eventually lyse due to
    ongoing activity of cell wall autolytic enzymes (autolysins and murein hydrolases) while cell
    wall assembly is arrested.

    Contraindications:

    • Hypersensitivity to cefuroxime, any component of the formulation, or other


    cephalosporins

    • Patients with known allergy to penicillins or cephalosphorins

    iNDICATION :

    · Both cefuroxime sodium and cefuroxime axetil is used in treating infections of Upper and
    Lower respiratory tract, skin and soft tissue, UTI, bone & joint infections and gonococcal
    infections.

    · Cefuroxime sodium on addition is indicated in treating serious infection pending


    bacteriological identification, Meningitis, Prophylaxis against infection in surgical procedures,
    Urinary infections, Patients with renal failure undergoing CAPD (continuous ambulatory
    peritoneal dialysis).

    · Cefuroxime axetil is also indicated in treating and preventing Lyme disease.

    ADVERSE REACTIONS :

    Anaphylaxis, pseudomembranous colitis, nausea and vomiting, transient elevation of liver


    enzymes.

    Adverse Reactions

    GI
    Nausea; vomiting; diarrhea; anorexia; abdominal pain or cramps; flatulence; colitis, including
    pseudomembranous colitis.

    Genitourinary

    Pyuria; renal dysfunction; dysuria; reversible interstitial nephritis; hematuria; toxic nephropathy.

    Hematologic

    Eosinophilia; neutropenia; lymphocytosis; leukocytosis; thrombocytopenia; decreased platelet


    function; anemia; aplastic anemia; hemorrhage.

    Hepatic

    Hepatic dysfunction; abnormal LFT results.

    Miscellaneous

    Hypersensitivity, including Stevens-Johnson syndrome, erythema multiforme, toxic epidermal


    necrolysis; candidal overgrowth; serum sickness–like reactions (eg, skin rashes, polyarthritis,
    arthralgia, fever); phlebitis, thrombophlebitis, and pain at injection site.

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