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    Site of Action of Drugs Acting On Adrenergic Neurohumoral Transmission PDF

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    Sunil
    This document outlines the sites of action of drugs acting on adrenergic neurohumoral transmission. It shows the pathways of tyrosine and dopamine synthesis and their conversion to norepinephrine, as well as the sites of action of various drugs that can stimulate or inhibit these pathways. These include (1) inhibitors of the enzymes involved in synthesis, (2) drugs similar to neurotransmitters that can be taken up, (3) uptake inhibitors, (4) receptor agonists and antagonists, and (5) inhibitors of the enzymes that break down the neurotransmitters.

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    Site of Action of Drugs Acting On Adrenergic Neurohumoral Transmission PDF

    Uploaded by

    Sunil
    269 views1 page
    This document outlines the sites of action of drugs acting on adrenergic neurohumoral transmission. It shows the pathways of tyrosine and dopamine synthesis and their conversion to norepinephrine, as well as the sites of action of various drugs that can stimulate or inhibit these pathways. These include (1) inhibitors of the enzymes involved in synthesis, (2) drugs similar to neurotransmitters that can be taken up, (3) uptake inhibitors, (4) receptor agonists and antagonists, and (5) inhibitors of the enzymes that break down the neurotransmitters.

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    Site of action of Drugs acting on Adrenergic Neurohumoral Transmission.pdf

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    Site of action of Drugs acting on Adrenergic Neurohumoral Transmission.pdf

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    This document outlines the sites of action of drugs acting on adrenergic neurohumoral transmission. It shows the pathways of tyrosine and dopamine synthesis and their conversion to norepinephrine, as well as the sites of action of various drugs that can stimulate or inhibit these pathways. These include (1) inhibitors of the enzymes involved in synthesis, (2) drugs similar to neurotransmitters that can be taken up, (3) uptake inhibitors, (4) receptor agonists and antagonists, and (5) inhibitors of the enzymes that break down the neurotransmitters.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    269 views1 page

    Site of Action of Drugs Acting On Adrenergic Neurohumoral Transmission PDF

    Uploaded by

    Sunil
    This document outlines the sites of action of drugs acting on adrenergic neurohumoral transmission. It shows the pathways of tyrosine and dopamine synthesis and their conversion to norepinephrine, as well as the sites of action of various drugs that can stimulate or inhibit these pathways. These include (1) inhibitors of the enzymes involved in synthesis, (2) drugs similar to neurotransmitters that can be taken up, (3) uptake inhibitors, (4) receptor agonists and antagonists, and (5) inhibitors of the enzymes that break down the neurotransmitters.

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    of 1

    SITE OF ACTION OF DRUGS ACTING ON ADRENERGIC NEUROHUMORAL TRANSMISSION

    Na+ LiverPhenyal alanine tyrosine K+


    STIMULATION INHIBITION

    TYROSINE

    ADRENERGIC NERVE TERMINAL

    1.ALPHA METHYL P-TYROSINE


    tyrosine hydroxylase

    DOPA
    DOPA decarboxylase

    2.ALPHA METHYL DOPA CARBIDOPA

    DOPAMNE
    SYNAPTIC VESICLE

    3.ALPHA METHYL DOPAMINE DOPAMNE


    Beta dopamine hydroxylase

    6.RESERPINE
    Inactive metabolites

    MAO
    Vesicula r uptake

    NOREPINEPHRINE [Type a quote from the document or (BOUND) the summary of an interesting point. You can position the text box NOREPINEPHRINE anywhere (FREE) in the document. Use the Text Box Tools tab to change the formatting of the pull quote text box.]

    Action PotentialCa2+

    7.MAO INHIBITORS NE NE
    EXOCYTOSIS

    4.TYRAMINE LIKE DRUGS: EPHEDRINE, TYRAMINE,AMPHETAMINE

    5.BRETYLIUM, GUANETHEDINE

    8.UPTAKE I INHIBITORS UPTAKE I 9. UPTAKE II INHIBITORS


    alpha 2 receptor

    10. ALPHA 2 AGONISTS


    NOR EPINEPHRINE COMT INHIBITORS

    COMT

    Inactive metabolites

    UPTAKE II

    11.ALPHA AGONISTS 12.BETA AGONISTS

    13. ALPHA BLOCKERS

    14.BETA BLOCKERS

    alpha 1 and 2 receptor

    EFFECTOR ORGAN RESPONSE/ EFFECT

    Beta receptor

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