Peppermint Water

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Romulus Jacob A.

Calanza 2011-51392

1. Official title: Peppermint Water, NF Category: Pharmaceutical Necessity Synonyms: Peppermint oil in purified water Uses: used principally as flavored or perfumed vehicle, carminative

Official definition: Peppermint water is a clear saturated solution of peppermint oil in purified water prepared by one of the processes described under aromatic waters

2.

Review of basic concepts: Name other examples of aromatic waters:

Strong Rose Water, USP Orange flower water Camphor water 3. Talc: (2 mL/ 1000 mL) (x g/ 10 mL)= 0.02 g Peppermint oil: (15 g/ 1000 mL) (x g/ 10 mL)= 0.15 g Determine the amount of ingredients needed to prepare 10 mL of Peppermint Water, NF:

4.

Give the use of each ingredient in the preparation:

Talc- breaks volatile substances into minute particles thereby exposed to solvent; it removes excess of the volatile substance and is insoluble in water, therefore easy to remove. It is also a dispersing agent. Peppermint oil- the gives flavor and taste Substitutes for talc- kielseghur, siliceous earth (clay), charcoal, chalk, magnesium carbonate

5.

What are the two methods of preparing aromatic waters:

Distillation- is the most ideal way for efficiency and quality of yield. It is slow and decomposition of essential oils and it may volatilize due to heat. Solution- more convenient in terms of time and equipment but the excess oils may be drawn off by water.

6. a.

Quality control parameters: Procedure:

Mix thoroughly 0.02 mL peppermint oil with 0.15 g talc. Add 7 mL purified water then shake for 10 minutes. Filter until it is clear and pass purified water through the filter to make 10 mL. b. Product:

Appearance- clear colorless solution Volume- 10 mL % Alcohol content- 0 % Pourability- easily pourable Physical stability- no floating impurities, no precipitation, no mold

7.

Packaging, labeling, and storage requirements:

Packaging: Packaging requirement- pack in tight containers Label- keep away from intense light Container- Amber narrow mouth bottle Cap- black with cap liner

Reference: Ansel, Howard, et. al. 2011. Ansels Pharmaceutical Dosage Forms and Drug Delivery Systems. New York. Wolters Kluwer.

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