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Receptor-Mediated Endocytosis: Process Diagrams Step-by-Step

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ENDOCYTOSIS

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Figure 3.

12 Receptor-mediated Endocytosis

Process Diagrams Step-by-Step

Copyright 2007 by John Wiley & Sons, Inc.

1 Binding Receptor-LDL complex LDL particle Receptor

Plasma membrane

Clathrin-coated pit

Invaginated plasma membrane

1 Binding Receptor-LDL complex LDL particle Receptor

Plasma membrane

Clathrin-coated pit

Invaginated plasma membrane 2 Vesicle formation Clathrin-coated vesicle

1 Binding Receptor-LDL complex LDL particle Receptor

Plasma membrane

Clathrin-coated pit

Invaginated plasma membrane 2 Vesicle formation Clathrin-coated vesicle 3 Uncoating

Uncoated vesicle

1 Binding Receptor-LDL complex LDL particle Receptor

Plasma membrane

Clathrin-coated pit

Invaginated plasma membrane 2 Vesicle formation Clathrin-coated vesicle 3 Uncoating

Uncoated vesicle 4 Fusion with endosome

Endosome

Transport vesicle

1 Binding Receptor-LDL complex LDL particle Receptor

Plasma membrane

Clathrin-coated pit

Invaginated plasma membrane 2 Vesicle formation Clathrin-coated vesicle 3 Uncoating

Transport vesicle

Uncoated vesicle 4 Fusion with endosome

5 Recycling of receptors to plasma membrane

Endosome

Transport vesicle

1 Binding Receptor-LDL complex LDL particle Receptor

Plasma membrane

Clathrin-coated pit

Invaginated plasma membrane 2 Vesicle formation Clathrin-coated vesicle 3 Uncoating

Transport vesicle

Uncoated vesicle 4 Fusion with endosome

5 Recycling of receptors to plasma membrane

Endosome

Transport vesicle

6 Degradation in lysosome

Digestive enzymes
Lysosome

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