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Nanotechnology in Medicine: A Presentation by Ruben Dax Sonz-Barnes & Sankarsh Ramachandra

Nanotechnology has applications in medicine known as nanomedicine. It can help develop improved biosensors and biomarkers to detect diseases through molecular imaging techniques. Nanoparticles can be tagged with luminescent markers to track cells and drug movement, capture functional information, and aid in disease diagnosis. Nanomedicine also aims to enhance drug delivery by using nanoparticles as vesicles to transport drugs, though early applications in the 1960s-1970s demonstrated nanoparticles could accidentally alter cell structure and trigger cell death due to their highly reactive surfaces.

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Nguyen Huu Hieu
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103 views5 pages

Nanotechnology in Medicine: A Presentation by Ruben Dax Sonz-Barnes & Sankarsh Ramachandra

Nanotechnology has applications in medicine known as nanomedicine. It can help develop improved biosensors and biomarkers to detect diseases through molecular imaging techniques. Nanoparticles can be tagged with luminescent markers to track cells and drug movement, capture functional information, and aid in disease diagnosis. Nanomedicine also aims to enhance drug delivery by using nanoparticles as vesicles to transport drugs, though early applications in the 1960s-1970s demonstrated nanoparticles could accidentally alter cell structure and trigger cell death due to their highly reactive surfaces.

Uploaded by

Nguyen Huu Hieu
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PPTX, PDF, TXT or read online on Scribd
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Nanotechnology in Medicine

A presentation by Ruben Dax SonzBarnes & Sankarsh Ramachandra

What is Nanotechnology?
Nanotechnology is the construction and use of functional structures designed from atomic or molecular scale with at least one characteristic dimension measured in nanometers. Their size allows them to exhibit novel and significantly improved physical, chemical, and biological properties, phenomena, and processes.
Source: http://www.nanoscience.gatech.edu/zlwang/research/nano.html

Nanomedicine
Nanomedicine is the medical application of nanotechnology, and ranges from the implementation of nanoelectric biosensors, to enhancement of drug delivery methods, and even possible future applications of molecular nanotechnology. Nanomedicine has incredible potential to revolutionize the detection and treatment of disease.

Biosensors/Biomarkers
Via molecular imaging, we can utilize nanotechnology to: Track groups of cells/movement of drugs with luminescent tags which attach themselves to proteins Capture functional information on both cellular/molecular processes Capture anatomical detail on molecular structure Identify/diagnose tumors and other diseases Yield better disease analysis in conjunction with nanoparticle usage to protect markers
Source: http://www.azonano.com/article.aspx?articleid=1242

White light nanoparticles Picture courtesy of: Nanogloss [http://nanogloss.com/nanoparticles/ white-lightnanoparticles/#axzz1OoeandDa]

Drug Delivery (Before)


In the 60s & 70s, applications of nanoparticles such as liposomes and dendrimers were used as vesicles to transport drugs into the body. This was dangerous, however, as those nanoparticles had the ability to accidentally alter cell structure and trigger apoptosis (cell death). The nanoparticles also possessed a high surface to volume ratio, which could make them extremely catalytic/reactive, increasing their susceptibility to cytotoxicity.
Source: Marshall, Maryann. "The Dangers of Nanoparticles." Independent News on Natural Health, Nutrition and More. Web. 25 May 2011.

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