Drug Name Mechanism of Action Indications Contraindications Adverse Effect Nursing Considerations
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Katrina PonceDrug Name Mechanism of Action Indications Contraindications Adverse Effect Nursing Considerations
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Katrina PonceDrug Name Generic name: Salbutamol
Mechanism of Action
Indications To control and prevent reversible airway obstruction caused by asthma or chronic obstructive pulmonary disorder (COPD) Quick relief for bronchospasm For the prevention of exercise-induced bronchospasm Long-term control agent for patients with chronic or persistent bronchospasm
Contraindications
Adverse Effect Nervousness Restlessness Tremor Headache Insomnia Chest pain Palpitations Angina Arrhythmias Hypertension Nausea and vomiting Hyperglycemia Hypokalemia
Nursing Considerations
Brand name: Alrovent
Route: Inhalation
Dosage: 2.5 ml
Frequency: q 12 hours
Classification Bronchodilator (therapeutic); adrenergics (pharmacologic)
It relieves nasal congestion and reversible bronchospasm by relaxing the smooth muscles of the bronchioles. The relief from nasal congestion and bronchospasm is made possible by the following mechanism that takes place when Salbutamol is administered. First, it binds to the beta2-adrenergic receptors in the airway of the smooth muscle which then leads to the activation of the adenyl cyclase and increased levels of cyclic- 35adenosine monophosphate (cAMP). When cAMP increases, kinases are activated. Kinases inhibit the phosphorylation of
Hypersensitivity to adrenergic amines Hypersensitivity to fluorocarbons
1. Assess lung sounds, PR and BP before drug administration and during peak of medication. 2. Observe fore paradoxical spasm and withhold medication and notify physician if condition occurs.
3. Administer PO medications with meals to minimize gastric irritation. 4. Extended-release tablet should be swallowedwhole. It should not be crushed or chewed. 5. If administering medication through inhalation, allow at least 1 minute between inhalation of aerosol
myosin and decrease intracellular calcium. Decreased in intracellular calcium will result to the relaxation of the smooth muscle airways.
medication. 6. Advise the patient to rinse mouth with water after each inhalation to minimize dry mouth. 7. Inform the patient that Albuterol may cause an unusual or bad taste.
