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    Spironolactone

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    Ninoska Garcia-Ortiz
    Spironolactone is a potassium-sparing diuretic prescribed to treat edema associated with congestive heart failure, hepatic cirrhosis, and nephritic syndrome. It works by promoting sodium and chloride excretion without loss of potassium. Major side effects include fatigue, nausea, vomiting, and electrolyte imbalances. When taking spironolactone, patients should be monitored for blood pressure, serum electrolytes, signs of fluid imbalance, and mental changes and notified not to replace fluid losses with excessive water or consume high potassium foods.

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    Spironolactone

    Uploaded by

    Ninoska Garcia-Ortiz
    5K views2 pages
    Spironolactone is a potassium-sparing diuretic prescribed to treat edema associated with congestive heart failure, hepatic cirrhosis, and nephritic syndrome. It works by promoting sodium and chloride excretion without loss of potassium. Major side effects include fatigue, nausea, vomiting, and electrolyte imbalances. When taking spironolactone, patients should be monitored for blood pressure, serum electrolytes, signs of fluid imbalance, and mental changes and notified not to replace fluid losses with excessive water or consume high potassium foods.

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    Spironolactone is a potassium-sparing diuretic prescribed to treat edema associated with congestive heart failure, hepatic cirrhosis, and nephritic syndrome. It works by promoting sodium and chloride excretion without loss of potassium. Major side effects include fatigue, nausea, vomiting, and electrolyte imbalances. When taking spironolactone, patients should be monitored for blood pressure, serum electrolytes, signs of fluid imbalance, and mental changes and notified not to replace fluid losses with excessive water or consume high potassium foods.

    Copyright:

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    Download as DOC, PDF, TXT or read online from Scribd
    Download as doc, pdf, or txt
    5K views2 pages

    Spironolactone

    Uploaded by

    Ninoska Garcia-Ortiz
    Spironolactone is a potassium-sparing diuretic prescribed to treat edema associated with congestive heart failure, hepatic cirrhosis, and nephritic syndrome. It works by promoting sodium and chloride excretion without loss of potassium. Major side effects include fatigue, nausea, vomiting, and electrolyte imbalances. When taking spironolactone, patients should be monitored for blood pressure, serum electrolytes, signs of fluid imbalance, and mental changes and notified not to replace fluid losses with excessive water or consume high potassium foods.

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    SPIRONOLACTONE

    1. Name & class of drug – generic and trade name.

    GENERIC NAME: Aldactone, Novospiroton


    BRAND NAME: Spironolactone
    CLASSIFICATION: Electrolyte and water balance agent; potassium sparing diuretic

    2. Dose range and routes for adult & geriatric client.

    PREPARATIONS: PO – (25, 50, 100) mg tablets

    DOSING: Edema – 25 – 200 mg/d in divided doses, continued for atleast 5 daysd

    3. Purpose prescribed. Underline reason your client is prescribed drug.

    THERAPEUTIC EFFECTS: a diuretic agent that promote sodium and chloride excretion without concomitant loss of K+.

    USES: clinical conditions associated with augmented aldosterone production, as in essential hypertension, refractory edema
    due to CHF, hepatic cirrhosis, nephritic syndrome and idiopathic edema

    4. Major side effects & drug interactions.

    DRUG INTERACTIONS: combination of spironolactone and acidifying doses of ammonium chloride may produce systemic
    acidosis. Effects may be antagonized by aspirin and other salicylates. Digoxin should be monitored for decreased effect.
    Hypokalemia may result with K+ supplements, ACE inhibitors, ARBS. May alter antiocoagulant response in warfarin. Salt
    subs may increase risk of hyperkalemia

    SIDE EFFECTS: lethargy, mental confusion, fatigue, N/V, abd cramps, fluid and electrolyte imbalance
    5. Nursing Implications & teaching.

    IMPLICATIONS:
    • Check blood pressure before initiation of therapy
    • Monitor serum electrolytes
    • Assess for signs for fluid electrolyte imbalance
    • Monitor daily I&O, check for edema
    • Weigh pt under standard conditions, and daily once therapy commences
    • Observe for and report immediately the onset of mental changes

    TEACHING:
    • Max diuretic effect may not occur until third day of therapy, diuresis may continue 2-3 days after d/c
    • Avoid replacing fluid losses with large amounts of free water
    • Weigh 2 – 3 times weekly
    • Avoid intake of high potassium foods and salt substitutes

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