Laparoscopic sacral colpopexy and a new approach to mesh fixation: a randomized clinical trial

Arch Gynecol Obstet. 2018 Nov;298(5):939-944. doi: 10.1007/s00404-018-4916-0. Epub 2018 Sep 25.

Abstract

Purpose: Laparoscopic sacral colpopexy (LSC) plus supracervical hysterectomy (LSH) for pelvic organ prolapse (POP) is a high-complexity surgical procedure. The aim of the present study was to evaluate a new approach to vaginal-mesh fixation during LSC with continuous locked suture.

Methods: This is a prospective randomized double-blinded clinical trial enrolling 90 patients with severe POP from January 2016 to April 2017. Patients underwent LSH plus a "two-meshes" LSC and were randomized, regarding mesh fixation, in Group 1 (extracorporeal interrupted 3-0 delayed absorbable sutures) and Group 2 (running locked 3-0 delayed absorbable suture). Our primary endpoints were the operative times and the secondary endpoints the incidence of intra- or post-operative complications.

Results: A total of 42 patients for group completed the study. Baseline characteristics were similar between the groups. Overall mesh fixation time (24 vs. 39 min; p < 0.01), and operative time (121 vs. 138 min; p < 0.05) resulted significantly lower in Group 2. No differences were found in terms of anatomic failure, vaginal mesh erosion or intra- or post-operative complications.

Conclusions: Laparoscopic continuous locked 3-0 absorbable suture for anterior and posterior mesh fixation during LSC guaranteed a faster and effective alternative to multiple interrupted sutures. The significant operative time reduction linked to this technique should be considered even more helpful when performing a highly complex surgery such as LSC.

Keywords: Continuous suture; Laparoscopy; Mesh fixation; Pelvic organ prolapse; Running suture; Sacral colpopexy.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Double-Blind Method
  • Female
  • Humans
  • Hysterectomy
  • Laparoscopy / methods*
  • Middle Aged
  • Operative Time
  • Pelvic Organ Prolapse / surgery*
  • Postoperative Complications / epidemiology
  • Prospective Studies
  • Sacrum
  • Surgical Mesh*
  • Suture Techniques*
  • Sutures
  • Treatment Outcome
  • Vagina / surgery