Acute effects of aerobic exercise intensity on arterial stiffness after glucose ingestion in young men

Clin Physiol Funct Imaging. 2018 Jan;38(1):138-144. doi: 10.1111/cpf.12395. Epub 2016 Oct 18.

Abstract

Arterial stiffness increases after glucose ingestion. Acute low- and moderate-intensity aerobic exercise decreases arterial stiffness. However, the acute effects of 30 min of cycling at low- and moderate-intensity [25% (LE trial) and 65% (ME trial) peak oxygen uptake, respectively] on arterial stiffness at 30, 60 and 120 min of a postexercise glucose ingestion. Ten healthy young men (age, 22·4 ± 0·5 years) performed LE and ME trials on separate days in a randomized controlled crossover fashion. Carotid-femoral (aortic) pulse wave velocity (PWV), femoral-ankle (leg) PWV, carotid augmentation index (AIx) and carotid blood pressure (BP) (applanation tonometry), brachial and ankle BP (oscillometric device), heart rate (HR) (electrocardiography), blood glucose (UV-hexokinase method) and blood insulin (CLEIA method) levels were measured at before (baseline) and at 30, 60 and 120 min after the 75-g OGTT. Leg PWV, ankle pulse pressure and BG levels significantly increased from baseline after the 75-g OGTT in the LE trial (P<0·05), but not in the ME trial. Insulin levels and HR significantly increased from baseline after the 75-g OGTT in both trials (P<0·05). Aortic PWV, carotid AIx, brachial BP and carotid BP did not change from baseline after the 75-g OGTT in both trials. The present findings indicate that aerobic exercise at moderate intensity before glucose ingestion suppresses increases leg arterial stiffness after glucose ingestion.

Keywords: acute aerobic exercise; blood glucose; exercise intensity; glucose ingestion; leg arterial stiffness.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Age Factors
  • Ankle Brachial Index
  • Blood Glucose / metabolism
  • Carotid Arteries / physiology*
  • Cross-Over Studies
  • Exercise / physiology*
  • Glucose / administration & dosage*
  • Glucose / metabolism
  • Glucose Tolerance Test
  • Humans
  • Insulin / blood
  • Lower Extremity / blood supply*
  • Male
  • Manometry
  • Muscle Contraction*
  • Pulse Wave Analysis
  • Sex Factors
  • Time Factors
  • Vascular Stiffness*
  • Young Adult

Substances

  • Blood Glucose
  • Insulin
  • Glucose