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Genetic interplay between HLA-C and MIR148A in HIV control and Crohn disease
Smita Kulkarni, Ying Qi, Colm O’hUigin, Florencia Pereyra, Veron Ramsuran, Paul McLaren, Jacques Fellay, George Nelson, Haoyan Chen, Wilson Liao, Sara Bass, Richard Apps, Xiaojiang Gao, Yuko Yuki, Alexandra Lied, Anuradha Ganesan, Peter W. Hunt, Steven G. Deeks, Steven Wolinsky, Bruce D. Walker, Mary Carrington
Proc Natl Acad Sci U S A. 2013 Dec 17; 110(51): 20705–20710. Published online 2013 Nov 18. doi: 10.1073/pnas.1312237110
PMCID:
PMC3870724
Abstract Article PDF–716K

Is Cited by the Following 53 Articles in this Archive:

Nucleotide alterations in the HLA-C class I gene can cause aberrant splicing and marked changes in RNA levels in a polymorphic context-dependent manner
Akiko Mizutani, Shingo Suzuki, Atsuko Shigenari, Tadayuki Sato, Masafumi Tanaka, Jerzy K. Kulski, Takashi Shiina
Front Immunol. 2023; 14: 1332636. Published online 2024 Jan 24. doi: 10.3389/fimmu.2023.1332636
PMCID:
PMC10847315
Abstract Article PDF–2.0M
Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution
Joyce B. Kang, Amber Z. Shen, Saisriram Gurajala, Aparna Nathan, Laurie Rumker, Vitor R. C. Aguiar, Cristian Valencia, Kaitlyn A. Lagattuta, Fan Zhang, Anna Helena Jonsson, Seyhan Yazar, Jose Alquicira-Hernandez, Hamed Khalili, Ashwin N. Ananthakrishnan, Karthik Jagadeesh, Kushal Dey, Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network, Mark J. Daly, Ramnik J. Xavier, Laura T. Donlin, Jennifer H. Anolik, Joseph E. Powell, Deepak A. Rao, Michael B. Brenner, Maria Gutierrez-Arcelus, Yang Luo, Saori Sakaue, Soumya Raychaudhuri
Nat Genet. Author manuscript; available in PMC 2024 Feb 1.
Published in final edited form as: Nat Genet. 2023 Dec; 55(12): 2255–2268. Published online 2023 Nov 30. doi: 10.1038/s41588-023-01586-6
PMCID:
PMC10787945
Abstract Article PDF–4.4M
“HLA-C: evolution, epigenetics, and pathological implications in the major histocompatibility complex”
Erick Velastegui, Edwin Vera, Wim Vanden Berghe, Mindy S. Muñoz, Andrea Orellana-Manzano
Front Genet. 2023; 14: 1206034. Published online 2023 Jul 3. doi: 10.3389/fgene.2023.1206034
PMCID:
PMC10350511
Abstract Article PDF–1.6M
Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution
Joyce B. Kang, Amber Z. Shen, Saori Sakaue, Yang Luo, Saisriram Gurajala, Aparna Nathan, Laurie Rumker, Vitor R. C. Aguiar, Cristian Valencia, Kaitlyn Lagattuta, Fan Zhang, Anna Helena Jonsson, Seyhan Yazar, Jose Alquicira-Hernandez, Hamed Khalili, Ashwin N. Ananthakrishnan, Karthik Jagadeesh, Kushal Dey, Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network, Mark J. Daly, Ramnik J. Xavier, Laura T. Donlin, Jennifer H. Anolik, Joseph E. Powell, Deepak A. Rao, Michael B. Brenner, Maria Gutierrez-Arcelus, Soumya Raychaudhuri
Version 1. medRxiv. Preprint. 2023 Mar 20. doi: 10.1101/2023.03.14.23287257
Published in:
Nat Genet. 2023 Dec; 55(12): 2255–2268.
PMCID:
PMC10055604
Abstract Article PDF–9.1M
Comparison between qPCR and RNA-seq reveals challenges of quantifying HLA expression
Vitor R. C. Aguiar, Erick C. Castelli, Richard M. Single, Arman Bashirova, Veron Ramsuran, Smita Kulkarni, Danillo G. Augusto, Maureen P. Martin, Maria Gutierrez-Arcelus, Mary Carrington, Diogo Meyer
Immunogenetics. 2023; 75(3): 249–262. Published online 2023 Jan 28. doi: 10.1007/s00251-023-01296-7
PMCID:
PMC9883133
Abstract Article PDF–1.2M
Inflammatory Bowel Diseases Are Associated with Polymyositis and Dermatomyositis—A Retrospective Cohort Analysis
Kassem Sharif, Niv Ben-Shabat, Muhammad Mahagna, Uria Shani, Abdulla Watad, Arnon D. Cohen, Howard Amital
Medicina (Kaunas) 2022 Dec; 58(12): 1727. Published online 2022 Nov 25. doi: 10.3390/medicina58121727
PMCID:
PMC9781532
Abstract Article PDF–308K
HLA allele-specific expression: Methods, disease associations, and relevance in hematopoietic stem cell transplantation
Tiira Johansson, Jukka Partanen, Päivi Saavalainen
Front Immunol. 2022; 13: 1007425. Published online 2022 Sep 28. doi: 10.3389/fimmu.2022.1007425
PMCID:
PMC9554311
Abstract Article PDF–533K
Influence of Disease Severity and Gender on HLA-C Methylation in COVID-19 Patients
Mohsen Sharif-zak, Mojtaba Abbasi-Jorjandi, Gholamreza Asadikaram, Zohreh-al-Sadat Ghoreshi, Mitra Rezazadeh-Jabalbarzi, Hamidreza Rashidinejad
Iran J Sci Technol Trans A Sci. 2022; 46(5): 1309–1316. Published online 2022 Jul 27. doi: 10.1007/s40995-022-01334-1
PMCID:
PMC9325662
Abstract Article PDF–584K
Regulation of HLA class I expression by non-coding gene variations
Florence Bettens, Halit Ongen, Guillaume Rey, Stéphane Buhler, Zuleika Calderin Sollet, Emmanouil Dermitzakis, Jean Villard
PLoS Genet. 2022 Jun; 18(6): e1010212. Published online 2022 Jun 6. doi: 10.1371/journal.pgen.1010212
PMCID:
PMC9170083
Abstract Article PDF–3.2M
The Effect of miRNA Gene Regulation on HIV Disease
Romona Chinniah, Theolan Adimulam, Louansha Nandlal, Thilona Arumugam, Veron Ramsuran
Front Genet. 2022; 13: 862642. Published online 2022 May 4. doi: 10.3389/fgene.2022.862642
PMCID:
PMC9117004
Abstract Article PDF–1.0M
Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease
Julie E. Horowitz, Jack A. Kosmicki, Amy Damask, Deepika Sharma, Genevieve H. L. Roberts, Anne E. Justice, Nilanjana Banerjee, Marie V. Coignet, Ashish Yadav, Joseph B. Leader, Anthony Marcketta, Danny S. Park, Rouel Lanche, Evan Maxwell, Spencer C. Knight, Xiaodong Bai, Harendra Guturu, Dylan Sun, Asher Baltzell, Fabricio S. P. Kury, Joshua D. Backman, Ahna R. Girshick, Colm O’Dushlaine, Shannon R. McCurdy, Raghavendran Partha, Adam J. Mansfield, David A. Turissini, Alexander H. Li, Miao Zhang, Joelle Mbatchou, Kyoko Watanabe, Lauren Gurski, Shane E. McCarthy, Hyun M. Kang, Lee Dobbyn, Eli Stahl, Anurag Verma, Giorgio Sirugo, Regeneron Genetics Center, Marylyn D. Ritchie, Marcus Jones, Suganthi Balasubramanian, Katherine Siminovitch, William J. Salerno, Alan R. Shuldiner, Daniel J. Rader, Tooraj Mirshahi, Adam E. Locke, Jonathan Marchini, John D. Overton, David J. Carey, Lukas Habegger, Michael N. Cantor, Kristin A. Rand, Eurie L. Hong, Jeffrey G. Reid, Catherine A. Ball, Aris Baras, Gonçalo R. Abecasis, Manuel A. R. Ferreira
Nat Genet. 2022; 54(4): 382–392. Published online 2022 Mar 3. doi: 10.1038/s41588-021-01006-7
PMCID:
PMC9005345
Abstract Article PDF–6.5M
HLA imputation and its application to genetic and molecular fine-mapping of the MHC region in autoimmune diseases
Tatsuhiko Naito, Yukinori Okada
Semin Immunopathol. 2022; 44(1): 15–28. Published online 2021 Nov 16. doi: 10.1007/s00281-021-00901-9
PMCID:
PMC8837514
Abstract Article PDF–1.7M
The New Kid on the Block: HLA-C, a Key Regulator of Natural Killer Cells in Viral Immunity
Sarah Vollmers, Annabelle Lobermeyer, Christian Körner
Cells. 2021 Nov; 10(11): 3108. Published online 2021 Nov 10. doi: 10.3390/cells10113108
PMCID:
PMC8620871
Abstract Article PDF–2.5M
Tight Regulation of Major Histocompatibility Complex I for the Spatial and Temporal Expression in the Hippocampal Neurons
Yuqing Shen, Jianqiong Zhang
Front Cell Neurosci. 2021; 15: 739136. Published online 2021 Oct 1. doi: 10.3389/fncel.2021.739136
PMCID:
PMC8517433
Abstract Article PDF–773K
An immunogenetic view of COVID-19
Vitor R. C. Aguiar, Danillo G. Augusto, Erick C. Castelli, Jill A. Hollenbach, Diogo Meyer, Kelly Nunes, Maria Luiza Petzl-Erler
Genet Mol Biol. 2021; 44(1 Suppl 1): e20210036. Published online 2021 Aug 25. doi: 10.1590/1678-4685-GMB-2021-0036
PMCID:
PMC8388242
Abstract Article PDF–3.7M
Relevance of Polymorphic KIR and HLA Class I Genes in NK-Cell-Based Immunotherapies for Adult Leukemic Patients
Léa Dubreuil, Patrice Chevallier, Christelle Retière, Katia Gagne
Cancers (Basel) 2021 Aug; 13(15): 3767. Published online 2021 Jul 27. doi: 10.3390/cancers13153767
PMCID:
PMC8345033
Abstract Article PDF–2.4M
Genome-wide analysis in 756,646 individuals provides first genetic evidence that ACE2 expression influences COVID-19 risk and yields genetic risk scores predictive of severe disease
J. E. Horowitz, J. A. Kosmicki, A. Damask, D. Sharma, G. H. L. Roberts, A. E. Justice, N. Banerjee, M. V. Coignet, A. Yadav, J. B. Leader, A. Marcketta, D. S. Park, R. Lanche, E. Maxwell, S. C. Knight, X. Bai, H. Guturu, D. Sun, A. Baltzell, F. S. P. Kury, J. D. Backman, A. R. Girshick, C. O’Dushlaine, S. R. McCurdy, R. Partha, A. J. Mansfield, D. A. Turissini, A. H. Li, M. Zhang, J. Mbatchou, K. Watanabe, L. Gurski, S. E. McCarthy, H. M. Kang, L. Dobbyn, E. Stahl, A. Verma, G. Sirugo, Regeneron Genetics Center, M. D. Ritchie, M. Jones, S. Balasubramanian, K. Siminovitch, W. J. Salerno, A. R. Shuldiner, D. J. Rader, T. Mirshahi, A. E. Locke, J. Marchini, J. D. Overton, D. J. Carey, L. Habegger, M. N. Cantor, K. A. Rand, E. L. Hong, J. G. Reid, C. A. Ball, A. Baras, G. R. Abecasis, M. A. Ferreira
Version 3. medRxiv. Preprint. NaN NaN [revised 2021 Jun 10]. doi: 10.1101/2020.12.14.20248176
Published in:
Nat Genet. 2022; 54(4): 382–392.
PMCID:
PMC7899471
Abstract Article PDF–9.4M
HLA RNA Sequencing With Unique Molecular Identifiers Reveals High Allele-Specific Variability in mRNA Expression
Tiira Johansson, Dawit A. Yohannes, Satu Koskela, Jukka Partanen, Päivi Saavalainen
Front Immunol. 2021; 12: 629059. Published online 2021 Feb 25. doi: 10.3389/fimmu.2021.629059
PMCID:
PMC7949471
Abstract Article PDF–2.1M
MiR34a Regulates Neuronal MHC Class I Molecules and Promotes Primary Hippocampal Neuron Dendritic Growth and Branching
Yue Hu, Wenqin Pei, Ying Hu, Ping Li, Chen Sun, Jiawei Du, Ying Zhang, Fengqin Miao, Aifeng Zhang, Yuqing Shen, Jianqiong Zhang
Front Cell Neurosci. 2020; 14: 573208. Published online 2020 Oct 28. doi: 10.3389/fncel.2020.573208
PMCID:
PMC7655649
Abstract Article PDF–2.7M
Single Nucleotide Polymorphism in KIR2DL1 Is Associated With HLA-C Expression in Global Populations
Luciana de Brito Vargas, Renata M. Dourado, Leonardo M. Amorim, Brenda Ho, Verónica Calonga-Solís, Hellen C. Issler, Wesley M. Marin, Marcia H. Beltrame, Maria Luiza Petzl-Erler, Jill A. Hollenbach, Danillo G. Augusto
Front Immunol. 2020; 11: 1881. Published online 2020 Aug 21. doi: 10.3389/fimmu.2020.01881
PMCID:
PMC7478174
Abstract Article PDF–879K
Polymorphism at rs9264942 is associated with HLA-C expression and inflammatory bowel disease in the Japanese
Hiroshi Suzuki, Satoru Joshita, Atsuhiro Hirayama, Akihiro Shinji, Kenji Mukawa, Minako Sako, Naoki Yoshimura, Tomoaki Suga, Takeji Umemura, Norihiro Ashihara, Tomoo Yamazaki, Masao Ota
Sci Rep. 2020; 10: 12424. Published online 2020 Jul 24. doi: 10.1038/s41598-020-69370-8
PMCID:
PMC7381613
Abstract Article PDF–1.3M
Capturing Differential Allele-Level Expression and Genotypes of All Classical HLA Loci and Haplotypes by a New Capture RNA-Seq Method
Fumiko Yamamoto, Shingo Suzuki, Akiko Mizutani, Atsuko Shigenari, Sayaka Ito, Yoshie Kametani, Shunichi Kato, Marcelo Fernandez-Viña, Makoto Murata, Satoko Morishima, Yasuo Morishima, Masafumi Tanaka, Jerzy K. Kulski, Seiamak Bahram, Takashi Shiina
Front Immunol. 2020; 11: 941. Published online 2020 May 29. doi: 10.3389/fimmu.2020.00941
PMCID:
PMC7272581
Abstract Article PDF–1.1M
HLA‐G whole gene amplification reveals linkage disequilibrium between the HLA‐G 3′UTR and coding sequence
Jos J. M. Drabbels, Robert Welleweerd, Inge van Rooy, Guro M. Johnsen, Anne Cathrine Staff, Geert W. Haasnoot, Nienke Westerink, Frans H. J. Claas, Erik Rozemuller, Michael Eikmans
HLA. 2020 Aug; 96(2): 179–185. Published online 2020 May 17. doi: 10.1111/tan.13909
PMCID:
PMC7384165
Abstract Article PDF–865K
The Dual Role of HLA-C in Tolerance and Immunity at the Maternal-Fetal Interface
Henrieta Papúchová, Torsten B. Meissner, Qin Li, Jack L. Strominger, Tamara Tilburgs
Front Immunol. 2019; 10: 2730. Published online 2019 Dec 9. doi: 10.3389/fimmu.2019.02730
PMCID:
PMC6913657
Abstract Article PDF–1.0M
An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer
Marian L. Burr, Christina E. Sparbier, Kah Lok Chan, Yih-Chih Chan, Ariena Kersbergen, Enid Y.N. Lam, Elizabeth Azidis-Yates, Dane Vassiliadis, Charles C. Bell, Omer Gilan, Susan Jackson, Lavinia Tan, Stephen Q. Wong, Sebastian Hollizeck, Ewa M. Michalak, Hannah V. Siddle, Michael T. McCabe, Rab K. Prinjha, Glen R. Guerra, Benjamin J. Solomon, Shahneen Sandhu, Sarah-Jane Dawson, Paul A. Beavis, Richard W. Tothill, Carleen Cullinane, Paul J. Lehner, Kate D. Sutherland, Mark A. Dawson
Cancer Cell. 2019 Oct 14; 36(4): 385–401.e8. doi: 10.1016/j.ccell.2019.08.008
PMCID:
PMC6876280
Abstract Article
Tumor-induced escape mechanisms and their association with resistance to checkpoint inhibitor therapy
Michael Friedrich, Simon Jasinski-Bergner, Maria-Filothei Lazaridou, Karthikeyan Subbarayan, Chiara Massa, Sandy Tretbar, Anja Mueller, Diana Handke, Katharina Biehl, Jürgen Bukur, Marco Donia, Ofer Mandelboim, Barbara Seliger
Cancer Immunol Immunother. 2019 Oct; 68(10): 1689–1700. Published online 2019 Aug 3. doi: 10.1007/s00262-019-02373-1
PMCID:
PMC11028168
Abstract Article PDF–809K
Expression estimation and eQTL mapping for HLA genes with a personalized pipeline
Vitor R. C. Aguiar, Jônatas César, Olivier Delaneau, Emmanouil T. Dermitzakis, Diogo Meyer
PLoS Genet. 2019 Apr; 15(4): e1008091. Published online 2019 Apr 22. doi: 10.1371/journal.pgen.1008091
PMCID:
PMC6497317
Abstract Article PDF–2.7M
The MHC in the Era of Next-Generation Sequencing: Implications for Bridging Structure with Function
Effie W. Petersdorf, Colm S. O’hUigin
Hum Immunol. Author manuscript; available in PMC 2020 Jan 1.
Published in final edited form as: Hum Immunol. 2019 Jan; 80(1): 67–78. Published online 2018 Oct 12. doi: 10.1016/j.humimm.2018.10.002
PMCID:
PMC6542361
Abstract Article PDF–767K
HIV-1-Associated Neurocognitive Disorders: Is HLA-C Binding Stability to β2-Microglobulin a Missing Piece of the Pathogenetic Puzzle?
Donato Zipeto, Michela Serena, Simona Mutascio, Francesca Parolini, Erica Diani, Elisabetta Guizzardi, Valentina Muraro, Emanuela Lattuada, Sebastiano Rizzardo, Marina Malena, Massimiliano Lanzafame, Giovanni Malerba, Maria Grazia Romanelli, Stefano Tamburin, Davide Gibellini
Front Neurol. 2018; 9: 791. Published online 2018 Sep 21. doi: 10.3389/fneur.2018.00791
PMCID:
PMC6160745
Abstract Article PDF–474K
Integration of Genome-Wide DNA Methylation and Transcription Uncovered Aberrant Methylation-Regulated Genes and Pathways in the Peripheral Blood Mononuclear Cells of Systemic Sclerosis
Honglin Zhu, Chengsong Zhu, Wentao Mi, Tao Chen, Hongjun Zhao, Xiaoxia Zuo, Hui Luo, Quan-Zhen Li
Int J Rheumatol. 2018; 2018: 7342472. Published online 2018 Sep 2. doi: 10.1155/2018/7342472
PMCID:
PMC6139224
Abstract Article PDF–5.2M