How Does Nerve Mechanical Interface Treatment Impact Pre-Surgical Carpal Tunnel Syndrome Patients? A Randomized Controlled Trial
Abstract
:1. Introduction
2. Materials and Methods
2.1. Design
2.2. Participants and Centers
2.3. Intervention
2.3.1. Intervention Group (IG)
2.3.2. Control Group (CG)
2.4. Outcome Measures
2.4.1. Primary Outcome
2.4.2. Secondary Outcome
2.5. Data Analysis
2.5.1. Sample Size Calculation
2.5.2. Statistical Analysis
3. Results
3.1. Between-Group Analyses
3.1.1. Boston Carpal Tunnel Questionnaire
3.1.2. Secondary Outcomes
3.2. Influence of Sociodemographic Variables
3.3. Patient Satisfaction
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Intervention Group (n = 20) | Control Group (n = 22) | p-Value | |
---|---|---|---|
Sex; n (%) | 0.721 | ||
Male | 8 (40%) | 10 (45.50%) | |
Female | 12 (60%) | 12 (54.50%) | |
Age (years) | 57.62 ± 8.24 | 60.37 ± 15.80 | 0.479 |
BMI (Kg·m2) | 31.16 ± 5.93 | 27.56 ± 4.84 | 0.036 |
Time with symptoms (years) | 4.00 (2.60) | 3.80 (3.00) | 0.563 |
Severity; n (%) | 0.349 | ||
Mild | 0 (0%) | 0 (0%) | |
Moderate | 5 (25%) | 3 (13.60%) | |
Severe | 15 (75%) | 19 (86.40%) | |
Bilaterality of symptoms; n (%) | 0.449 | ||
Yes | 18 (90%) | 18 (81.80%) | |
No | 2 (10%) | 4 (18.20%) | |
Patient’s perception of the etiology cause; n (%) | 0.758 | ||
None | 4 (20%) | 5 (22.70%) | |
Work | 13 (65%) | 12 (54.50%) | |
Age | 1 (5%) | 1 (4.50%) | |
Comorbidities | 1 (5%) | 2 (9.10%) | |
Other | 2 (10%) | 2 (9.10%) | |
Presence of comorbidities; n (%) | 0.067 | ||
Yes | 16 (80%) | 17 (77.30%) | |
No | 4 (20%) | 5 (22.70%) | |
Number of comorbidities; n (%) | 0.572 | ||
None | 5 (25%) | 5 (22.70%) | |
One | 8 (40%) | 5 (22.70%) | |
Two or more | 7 (35%) | 12 (54.60%) | |
Physical activity; n (%) | 0.303 | ||
150–300 min/week moderate or 75–150 min/week of vigorous aerobic activity | 6 (30%) | 10 (45.50%) | |
None | 14 (70%) | 12 (54.50%) | |
Actual profession; n (%) | 0.366 | ||
Active | 13 (65%) | 11 (50%) | |
Inactive | 7 (35%) | 11 (50%) | |
Work status; n (%) | 0.297 | ||
Employed | 13 (65%) | 11 (50%) | |
Off work | 1 (5%) | 2 (9.10%) | |
Unemployed | 3 (15%) | 1 (4.50%) | |
Retired | 3 (15%) | 8 (36.40%) | |
Alcohol consumption; n (%) | 0.846 | ||
Daily | 3 (15%) | 4 (18.20%) | |
Weekly | 6 (30%) | 5 (22.70%) | |
Monthly | 4 (20%) | 3 (13.60%) | |
No | 7 (35%) | 10 (45.50%) | |
Tabacco consumption; n (%) | 0.580 | ||
Yes | 16 (80%) | 19 (86.40%) | |
No | 4 (20%) | 3 (13.60%) |
T1—After Treatment | T2—3 Months | T3—6 Months | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mean ± SD | F | p-Value | η2 Power | Mean ± SD | F | p-Value | η2 Power | Mean ± SD | F | p-Value | η2 Power | ||
Boston Carpal Tunnel Questionnaire | |||||||||||||
Symptom Severity Scale (1–5) | CG | 3.20 ± 0.61 | 22.93 | <0.001 * | 0.37 0.99 | 3.20 ± 0.76 | 11.99 | 0.001 * | 0.24 0.92 | 3.11 ± 0.75 | 13.24 | 0.001 * | 0.25 0.94 |
IG | 2.45 ± 0.72 | 2.39 ± 0.81 | 2.29 ± 0.71 | ||||||||||
Function Severity Scale (1–5) | CG | 2.47 ± 0.66 | 9.72 | 0.003 * | 0.20 0.86 | 2.41 ± 0.68 | 7.44 | 0.010 * | 0.16 0.76 | 2.53 ± 0.69 | 8.47 | 0.006 * | 0.23 0.81 |
IG | 1.67 ± 0.70 | 1.62 ± 0.74 | 1.68 ± 0.70 | ||||||||||
Pain intensity (0–100) | CG | 48.2 ± 23.4 | 40.39 | <0.001 * | 0.51 0.99 | 54.0 ± 24.2 | 12.63 | 0.001 * | 0.25 0.93 | 56.4 ± 24.6 | 21.56 | <0.001 * | 0.36 0.99 |
IG | 15.7 ± 11.6 | 28.4 ± 23.5 | 24.0 ± 20.2 | ||||||||||
Hand mechanical threshold (1.65–6.65) | CG | 3.29 ± 0.54 | 1.82 | 0.186 | 0.04 0.26 | 3.24 ± 0.49 | 4.17 | 0.048 * | 0.10 0.51 | 3.10 ± 0.42 | 3.53 | 0.068 | 0.08 0.45 |
IG | 3.11 ± 0.80 | 2.96 ± 0.64 | 2.87 ± 0.46 | ||||||||||
Hand grip strength (Kg) | CG | 20.6 ± 10.0 | 0.054 | 0.817 | 0.01 0.06 | 21.1 ± 10.7 | 0.012 | 0.914 | 0.01 0.05 | 20.3 ± 9.5 | 3.72 | 0.061 | 0.09 0.47 |
IG | 24.9 ± 10.8 | 24.6 ± 9.3 | 26.7 ± 8.4 | ||||||||||
ULNT1 (°) | CG | 92.5 ± 7.9 | 91.61 | <0.001 * | 0.70 0.99 | 91.8 ± 7.0 | 34.68 | <0.001 * | 0.47 0.99 | 91.7 ± 3.6 | 44.12 | <0.001 * | 0.53 0.99 |
IG | 140.4 ± 19.6 | 128.9 ± 24.6 | 125.6 ± 21.2 | ||||||||||
Tampa Scale (11–44) | CG | 28.5 ± 8.6 | 6.32 | 0.016 * | 0.14 0.69 | 27.0 ± 9.1 | 1.36 | 0.250 | 0.25 0.21 | 27.4 ± 8.0 | 4.39 | 0.043 * | 0.10 0.53 |
IG | 23.3 ± 6.2 | 23.3 ± 7.0 | 22.4 ± 25.2 |
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Hernández-Secorún, M.; Abenia-Benedí, H.; Lucha-López, M.O.; Durán-Serrano, M.; Hamam-Alcober, J.S.; Krauss, J.; Hidalgo-García, C. How Does Nerve Mechanical Interface Treatment Impact Pre-Surgical Carpal Tunnel Syndrome Patients? A Randomized Controlled Trial. J. Pers. Med. 2024, 14, 801. https://doi.org/10.3390/jpm14080801
Hernández-Secorún M, Abenia-Benedí H, Lucha-López MO, Durán-Serrano M, Hamam-Alcober JS, Krauss J, Hidalgo-García C. How Does Nerve Mechanical Interface Treatment Impact Pre-Surgical Carpal Tunnel Syndrome Patients? A Randomized Controlled Trial. Journal of Personalized Medicine. 2024; 14(8):801. https://doi.org/10.3390/jpm14080801
Chicago/Turabian StyleHernández-Secorún, Mar, Hugo Abenia-Benedí, María Orosia Lucha-López, María Durán-Serrano, Javier Sami Hamam-Alcober, John Krauss, and César Hidalgo-García. 2024. "How Does Nerve Mechanical Interface Treatment Impact Pre-Surgical Carpal Tunnel Syndrome Patients? A Randomized Controlled Trial" Journal of Personalized Medicine 14, no. 8: 801. https://doi.org/10.3390/jpm14080801