Fast-Setting Calcium Silicate-Based Pulp Capping Cements—Integrated Antibacterial, Irritation and Cytocompatibility Assessment
Abstract
:1. Introduction
2. Material and Methods
2.1. Calcium Silicate-Based Cements
2.2. Topography and Elemental Analysis of the Set Cements
2.3. In Vitro Prevention of Antibiofilm Formation by the Set Cements
2.4. In Vivo Irritation Potential of the Undiluted Extracts
2.5. In Vitro Cytocompatibility of the Extracts
2.6. Statistical Analysis
3. Results
3.1. Topography and Elemental Composition of the Set Cements
3.2. Prevention of Antibiofilm Formation
3.3. In Vivo Irritation Potential
3.4. Cytotoxicity to Eukaryotic Cells
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Material | Composition | Manufacturer | Batch No. |
---|---|---|---|
Dycal® | Base paste: titanium dioxide, barium sulphate, glycol disalicylate Catalyst paste: calcium hydroxide, zinc oxide, zinc stearate, ethyl toluene sulphonamide | Dentsply DeTrey GmbH, Dresden, Germany | 00071192 |
ProRoot® MTA | Tricalcium silicate, dicalcium silicate, tricalcium aluminate and calcium sulfate | Dentsply DeTrey GmbH, Dresden, Germany | 0000301574 |
BiodentineTM | Powder: tricalcium silicate, dicalcium silicate, calcium carbonate, iron oxide, zirconium oxide Liquid: water with calcium chloride and soluble polymer (polycarboxylate) | Septodont, Saint-Maur-des-Fossés, France | B27532 |
TotalFill® BC RRMTM Fast Putty | Zirconium oxide, tantalum oxide, calcium silicate, calcium phosphate monobasic and fillers | FKG Dentaire SA, La Chaux-de-Fonds, Switzerland | 2100004308 |
Theracal LC® | Portland cement, BisGMA, barium zirconate | Bisco, INC., Schaumburg, IL, USA | 2100004308 |
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Kato, G.; Gomes, P.S.; Neppelenbroek, K.H.; Rodrigues, C.; Fernandes, M.H.; Grenho, L. Fast-Setting Calcium Silicate-Based Pulp Capping Cements—Integrated Antibacterial, Irritation and Cytocompatibility Assessment. Materials 2023, 16, 450. https://doi.org/10.3390/ma16010450
Kato G, Gomes PS, Neppelenbroek KH, Rodrigues C, Fernandes MH, Grenho L. Fast-Setting Calcium Silicate-Based Pulp Capping Cements—Integrated Antibacterial, Irritation and Cytocompatibility Assessment. Materials. 2023; 16(1):450. https://doi.org/10.3390/ma16010450
Chicago/Turabian StyleKato, Gabriel, Pedro Sousa Gomes, Karin Hermana Neppelenbroek, Cláudia Rodrigues, Maria Helena Fernandes, and Liliana Grenho. 2023. "Fast-Setting Calcium Silicate-Based Pulp Capping Cements—Integrated Antibacterial, Irritation and Cytocompatibility Assessment" Materials 16, no. 1: 450. https://doi.org/10.3390/ma16010450