Exact Sciences’ Post

A breakthrough paper in Nature describes driver mutations in colorectal cancer based on tumor DNA sequencing in over 2,000 patients! Colorectal cancer is the 3rd most common cancer. This paper highlights genetic underpinnings of colon cancer. This is why at PUER, we test the entire inherited, germline genome using whole genome sequencing. Whole genome sequencing is the anchor for PUER’s multiomic approach. PUER is the scientific and bespoke multigenerational concierge program for health, wellness, and longevity!

🚀 Revolutionizing Colorectal Cancer Treatment: Groundbreaking Study Unveils Key Genetic Drivers A new Nature paper uncovers critical driver mutations in colorectal cancer from DNA sequencing 2,000+ patients. At PUER, our whole genome sequencing anchors a cutting-edge, multiomic approach for personalized health and wellness! #PUER #PUERInsight #CancerResearch #longevity #health #wellness #healthspan #lifespan #wellness #healthyaging #futureofhealth #cancer #DNA #PrecisionMedicine #CancerScreening #HealthInnovation

New approaches to liquid biopsy are being discussed at #PMWC to impact patient care over the cancer care continuum. Daniel De Carvalho, PhD from Adela, Inc. shares the importance of measuring cell-free methylated DNA to understand the changes in cancer biology for dynamic patient monitoring. This will help us better determine how to treat the patient. #precisionmedicine #liquidbiopsy

Discover the power of genomic testing in the fight against breast cancer. Exact Sciences is here to offer advanced genomic testing to help with personalized treatment plans and improving outcomes. #BreastCancerAwareness #OncotypeDX #OncoExTra

Our latest eBook highlights the advanced technologies transforming cancer biology. Learn how these technologies are setting new standards in the accuracy and effectiveness of cancer diagnostics and treatment.  #CancerResearch #Innovation https://lnkd.in/g8V2xu-J

🔍 Defining minimal standards for #datacollection is key to creating interoperative, searchable genomic and clinical databases. Today’s #ELIXIRFridayReads is an article on 1+MG minimal dataset for #cancer. 🙌 The authors highlighted the 1+Million Genomes Minimal Dataset for Cancer, encompassing 140 items in 8 domains to foster the collection of #cancerdata, inform transnational cooperation and advance precision cancer medicine. Read more 👉 https://lnkd.in/eCUKCrz5 #1MGenomes

The age of cancer biomarkers and precision medicine begins with the discovery that HER2 is overexpressed in 20-25% of breast cancers and is associated with adverse outcomes. Herceptin, the first Ab therapeutic for the treatment of solid tumors that blocks the HER2 receptor, is approved in 1998, and ushers in the rise of targeted cancer treatments. What new biomarkers will you discover with spatial biology? Join our panel discussion tomorrow sponsored by Illumina and Life Science Washington to learn how our speakers are using spatial multiomics to advance research on women’s health. 👉https://bit.ly/3VhFfCP #cancertreatment #precisionmedicine #spatialbiology #biomarkerdiscovery #womenshealthwednesdays

Do you want to uncover the basic biology underlying this hallmark of cancer, and to exploit it to target cancer cells and eliminate tumors? Meet Professor Uri Ben-David, who uses state-of-the-art genomic and functional approaches to investigate why cancer cells are aneuploid, and how their aneuploidy can be used against them. Uri Ben-David

Delighted to announce our next publication titled: "GLUT and HK: Two Primary and Essential Key Players in Tumor Glycolysis" in Seminars in Cancer Biology (Impact factor-15). Our study delves deep into the intricate mechanisms of tumor glycolysis, shedding light on the pivotal roles played by GLUT and HK proteins. Through rigorous investigation, we uncover crucial insights that could revolutionize cancer treatment strategies. For those interested in exploring the complexities of tumor metabolism and its implications for cancer therapy, this article is a must-read. DOI- 10.1016/j.semcancer.2024.03.001 Gratitude and best wishes to all the co-authors and Prof. Vinit Kumar for guiding us. #CancerResearch #TumorGlycolysis #ScientificPublication #GLUT #HK #SeminarsinCancerBiology #ScientificDiscovery

Data from the 100,000 Genomes Project highlights that the most frequently mutated genes are not always included in current genomic panels, drawing support for moving whole-genome sequencing into the clinic. Read more from the largest whole-genome sequencing study in cancer: https://ow.ly/oZbr50RKkw8 #CancerResearch #PrecisionOncology