Director/Senior Director, Project Management

Job Type

Full-time

Description

Position Title: Director/Senior Director, Project Management

Reports to: Head of Project Leadership

Company Background

Century Therapeutics, an innovative biotechnology company, is developing novel allogeneic living cell products for oncology and autoimmune diseases that overcome the limitations of current cell therapies. Century’s genetically-engineered, universal iPSC-derived immune effector cell products are designed to specifically target oncologic and autoimmune indications. Our commitment to developing off-the-shelf cell therapies will expand patient access and provide an unparalleled opportunity to advance the care of patients with high unmet need.

Century’s foundational technology is built on induced pluripotent stem cells (iPSCs) that have unlimited self-renewing capacity. This enables complex cellular engineering to produce controlled cell banks of modified cells that can be expanded and differentiated into desired immune effector cells, which can supply vast amounts of allogeneic, homogeneous therapeutic products. Key to Century’s platform is our Allo-EvasionTM technology that allows repeat dosing of the allogeneic product without allo-rejection. This platform differentiates Century from other approaches that utilize non-renewable donor-derived cells.

Role

This position reports directly to the Head of Project Leadership. The candidate will facilitate and manage cross-functional drug development teams through preclinical and clinical phases, focused on the development of Century’s novel iPSC-derived allogeneic iNK and iT cell therapies in oncologic and autoimmune indications. S/he will guide cross-functional teams for Century’s pipeline to successfully progress projects, timelines, and budgets, in collaboration with functional leads. S/he will be a driver of project management, portfolio, and governance excellence for Century.

Responsibilities

• Drive and manage allogeneic iPSC-derived targeted cell therapy therapeutic development projects in hematology, oncology, and autoimmune diseases, from preclinical development through clinical proof of concept, in collaboration with cross-functional project teams.
• Facilitate Drug Candidate selection-enabling, IND-enabling & clinical Phase I/II-enabling activities, including research, nonclinical safety, CMC, translational, regulatory, clinical and clinical operations activities.
• Strategic leadership to analyze scenarios and define options for programs.
• Along with functional leads, drive program strategy and decision making, considering impact to timelines, resources, budget.
• Independently lead sub teams reporting into through the project team
• Develop, own, and manage timelines and team tools.
• Identify project risks and issues; work with functional experts to mitigate and resolve.
• Develop and coordinate resource and budget planning.
• Prepare agendas, minutes, progress reports.
• Communicate effectively across all functional areas so that deliverables and interdependencies are clear.
• Ensure high-performing teams.
• Responsible for >1 pipeline project across indications.
• May directly manage alliance programs and serve as point of contact with partners.
• Ensure that all activities comply with company SOPs, GxPs, and any regional specific regulations.
• Define, recommend, and implement project management operational needs.
  
  

Qualifications

• Bachelor’s degree in science or engineering required. Advanced degree desirable (MS, MBA, PharmD, or PhD).
• +10 years of relevant biopharmaceutical experience.
• A minimum of 6 years project management in cross-functional drug development or team role required.
  
  

Requirements

• Direct project management experience in a therapeutic drug development setting in hematology, oncology, or autoimmune disease areas.
• Project management experience from IND-enabling phase to Phase I/II clinical studies.
• Experience in cell therapies, gene therapy, biologics, or vaccine development.
• Familiarity with regulatory requirements (e.g., FDA regulations, and ICH /GxP guidelines), technical (CMC) requirements, and clinical study execution.
• Alliance management or collaboration experience desired.
• Excellent project management, communication, and cross-functional collaboration skills, with a results-driven mindset.
• Able to motivate and develop individual team members and overall team performance.
• Proven ability to effectively manage conflicts and negotiations while providing impact and influence.
• Excellent organizational, analytical, and planning skills.
• Robust proficiency in project management and collaboration support tools and systems.
• Strong initiative and “can do” attitude, and dedicated work ethic.
  
  

Experience with industry-standard project management timeline and tracking tools (MS Project, Smartsheet) preferred.

Century Therapeutics Inc. is an Equal Employment Opportunity/Affirmative Action Employer - Minority/Female/Disability/Veteran. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or veteran status or any other characteristic protected by federal, state, or local law.