Exciting news from our portfolio company Accent Therapeutics, Inc. on receiving IND clearance for ATX-559, a first-in-class oral #DHX9 inhibitor. ATX-559 Phase 1/2 trial (NCT06625515) will focus on patients with BRCA1/2-deficient breast cancer and MSI-H and/or dMMR cancers to evaluate safety, tolerability, PK/PD, and preliminary efficacy of ATX-559. Press release: https://lnkd.in/gXQQVKXV Mirae Asset Capital Life Science and the affiliates are pleased to support Shakti Narayan and the Accent team in making this breakthrough in developing and advancing a first-in-class DHX9 inhibitor and pushing the boundaries in #PrecisionOncology. Naveen Krishnan David Paik Daniel Kwon Ray Hyo Won Ahn Hansoo Kim Mirae Asset Capital #DHX9 #breastcancer #MSIhigh #dMMR #KIF18A #Oncology #AccentTherapeutics #biotech
📢 NEWS: The FDA has cleared our Investigational New Drug (IND) application for ATX-559, our first-in-class oral DHX9 inhibitor, paving the way for a Phase 1/2 trial focused on patients with BRCA1/2-deficient breast cancer and solid tumors with microsatellite instability and/or deficient mismatch repair (NCT06625515). Learn more: https://bit.ly/40bAbmq #cancerresearch #drugdevelopment #DHX9 #clinicaltrial #breastcancer #colorectalcancer