In 1993, Cassidy had a malignant mole removed from her back. Three years later, during a promotional event for the Live at Blues Alley album in July 1996, Cassidy noticed an ache in her hips, which she attributed to stiffness from painting murals while perched atop a stepladder. The pain persisted and a few weeks later, X-rays revealed that the melanoma had spread to her lungs and bones. Her doctors estimated she had three to five months to live. Cassidy opted for aggressive treatment, but her health deteriorated rapidly. In the early autumn, at a benefit concert for her at the Bayou, she made her final public appearance, closing the set with "What a Wonderful World" in front of an audience of family, friends, and fans. Additional chemotherapy was ineffective and Cassidy died on November 2, 1996 at her family's home in Bowie, Maryland. In accordance with her wishes, her body was cremated and the ashes were scattered on the lake shores of St. Mary's River Watershed Park, a nature reserve near Callaway, Maryland.