Inman, "The genetic basis of ankylosing
spondylitis: new insights into disease pathogenesis," Application of Clinical Genetics, vol.
Abbreviations 25(OH)[D.sub.3]: 25-Hydroxycholecalciferol 1,25-[(OH).sub.2]: 1,25-Dihydroxycholecalciferol [D.sub.3] AS: Ankylosing
spondylitis AIDS: Acquired immunodeficiency syndrome BASDAI: Bath Ankylosing
Spondylitis Disease Activity Index BASFI: Bath Ankylosing
Spondylitis Functional Index BMD: Bone mineral density CRP: C-reactive protein CVD: Cardiovascular diseases DC: Dendritic cells DMARDs: Disease-modifying antirheumatic drugs ESR: Erythrocyte sedimentation rate HLA: Human leukocyte antigen IL: Interleukin IOM: Institute of Medicine MHC: Major histocompatibility complex NSAIDs: Nonsteroidal anti-inflammatory drugs Th: T helper TNF-[alpha]: Tumor necrosis factor alpha TNFi: Tumor necrosis factor inhibitors VDR: Vitamin D receptor.
Eli Lilly and Company (NYSE: LLY), a US-based pharmaceutical company, announced yesterday that the US Food and Drug Administration (FDA) has approved Taltz(R) (ixekizumab) injection 80mg/mL for the treatment of adults with active ankylosing
spondylitis (AS), also known as radiographic axial spondyloarthritis (r-axSpA).
Food and Drug Administration (FDA) has approved Taltz (ixekizumab) injection 80 mg/mL for the treatment of adults with active ankylosing
spondylitis (AS), also known as radiographic axial spondyloarthritis (r-axSpA).
The Ankylosing
Spondylitis Disease Activity Scale (ASDAS), Bath Ankylosing
Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing
Spondylitis Functional Index (BASFI), and Bath Ankylosing
Spondylitis Metrology Index (BASMI) scores were calculated for all patients.
In fact, as high as eighty percent of AS patients get the diagnosis before age 30, according to the
Spondylitis Association of America.
'Despite the seriousness of this disease, awareness of ankylosing
spondylitis is very low.
Ankylosing
spondylitis patients for whom full blood was available were selected from an existing disease registry for AS in Northern Norway.
He then discussed the ankylosing
spondylitis classification criteria in patients who have already been diagnosed.
Taltz also met the major secondary endpoints at week 16 and week 52, including improvement in Ankylosing
Spondylitis Disease Activity Score, or ASDAS, significant improvement in Bath Ankylosing
Spondylitis Disease Activity, or BASDAI, proportion of patients achieving low disease activity, improvement in sacroiliac joint inflammation as assessed by MRI and improvement in 36-Item Short Form Health Survey, or SF-36, physical component summary score.
Ankylosing
spondylitis is diagnosed under these parameters: pain persisting for more than three months, back pain with stiffness that worsens with immobility and that occurs especially at night and early morning.
Summary: New Delhi, [India] Nov 23 (ANI): Young adults in their late twenties and early thirties are experiencing a chronic condition called Ankylosing
Spondylitis (AS).
Objective: Ankylosing
Spondylitis (AS) is an inflammatory rheumatic disease that mainly affects the axial spine.
Recent studies have identified sensorineural hearing loss as a possible manifestation of ankylosing
spondylitis. We conducted a study of 30 patients with ankylosing
spondylitis to characterize their audiologic profile and to correlate their disease activity and functional indices with their hearing thresholds.
