Pathogenesis of sciatic pain: role of herniated nucleus
pulposus and deformation of spinal nerve root and dorsal root ganglion.
Secondly, in adults, it involves annulus fibrosus in addition to nucleus
pulposus. Thirdly, it is mainly a degenerative process; however, it can also reflect a systemic disease.
Efficacy of a new navigable percutaneous disc decompression device (L'DISQ) in patients with herniated nucleus
pulposus related to radicular pain.
* 4th stage is sequestration where nucleus
pulposus breaks through the annulus fibrosus and moves outside the disc.
(23) Yeung's technique borrowed from Kambin's arthroscopic discectomy technique (24) and Schreiber and Suezawa's use of injecting indigo carmine into the disc space to stain the abnormal nucleus
pulposus and annular fissures.
Scientists trying to find early therapy options to fight degenerative disc disease have shown considerable interest in harnessing stem cells to restore nucleus
pulposus.
Spinal cord infarction secondary to nucleus
pulposus embolization in pregnancy.
Total ADC values of L1 intervertebral discs in Groups A (0.00154 [+ or -] 0.00008), B (0.00130 [+ or -] 0.00005), C (0.00122 [+ or -] 0.00007), and D (0.00107 [+ or -] 0.00007) significantly decreased with age ( P < 0.01); nucleus
pulposus ADC values of L1 intervertebral discs in Groups A (0.00164 [+ or -] 0.00005), B (0.00156 [+ or -] 0.00007), C (0.00147 [+ or -] 0.00008), and D (0.00140 [+ or -] 0.00007) significantly decreased with age ( P < 0.01); annulus fibrosis ADC values of L1 intervertebral discs in Groups A (0.00129 [+ or -] 0.00014), B (0.00110 [+ or -] 0.00011), C (0.00095 [+ or -] 0.00009), and D (0.00082 [+ or -] 0.00012) significantly decreased with age ( P < 0.01).
Park, "Effect of high glucose on stress-induced senescence of nucleus
pulposus cells of adult rats," Asian Spine Journal, vol.
Xu, "Effect of Yaobitong capsule on histomorphology of dorsal root ganglion and on expression of p38mark phosphorylation in autologous nucleus
pulposus transplantation model of rats," Asian Pacific Journal of Tropical Medicine, vol.
Evidence has been found in latest researches that nucleus
pulposus mesenchymal stem cells (NP-MSCs) exist naturally in the IVD [10, 11] and participate in IVD regeneration [9].
Whitecloud, "A comparison of computed tomography-myelography, magnetic resonance imaging, and myelography in the diagnosis of herniated nucleus
pulposus and spinal stenosis," Journal of Spinal Disorders, vol.
Intradiscal electrothermal treatment has been used by specialists for more than ten years in discogenic pain treatment.3 Collagen structure of the disc is changed and nociceptors are coagulated by penetrating into nucleus
pulposus through annulus fibrosis posterior using a percutaneous needle or a cannula in intradiscal treatment techniques similar to IDET.3 Clinical success of the procedure is generally about 60%.3 Complications may develop after the procedure.
Compressive forces in the intervertebral discs are predominately handled by the nucleus
pulposus which is also made up of PGs within a loose framework of collagen fibers.
It results in the degeneration of the intervertebral disc--especially the nucleus
pulposus, the soft hydrated center of the disc--the jelly part of the doughnut.
