helper T cell

The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding.

Wilson et al., "Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus," Arthritis and Rheumatism, vol.

Meanwhile, concentrations of healthy helper T cells in the patients remained steady.

Wong et al., "Follicular helper T cells are required for systemic autoimmunity," Journal of Experimental Medicine, vol.

Heterogeneity of cytokine secretion patterns and functions of helper T cells. Adv Immunol 46:111-145.

Helper T cells are alerted of imminent danger by the cytokines of other cells of the immune system.

These class II major histocompatibility complex (MHC) proteins present the peptides to immune cells called helper T cells, which coordinate the body's response.

For the immune system to respond to a protein with a finely tuned, high-affinity antibody response, antigen-specific CD[4.sup.+] helper T cells must be activated.

London, January 21 ( ANI ): Researchers have discovered the mechanism that enables CD4 helper T cells to assume the more aggressive role of killer T cells in mounting an immune attack against viruses, cancerous tumors and other damaged or infected cells.

Although the basic cause of rheumatoid arthritis remains unclear, immune cells known as CD4 helper T cells seem to carry some blame.

In addition to getting instructions from the antigen-presenting cells, CD8 T cells need assistance from helper T cells to become effective killers.