Unlike folic acid, this biologically active form of
folate is easy for the body to metabolize: its formula does not require any extra steps to be absorbed and enter circulation once ingested.
The goal of the present study was to determine if varying
folate intake modifies iAs metabolism and metabolic phenotype in wild-type (WT) male and female C57BL/6J mice exposed to iAs in drinking water (100 ppb), with and without a high-fat diet (HFD) as an additional metabolic stressor.
This partnership with Merck KGaA will allow for a broader application of ITM's Theranostics platform to include diagnosis and therapy of patients with
folate receptor-positive cancers.
Perhaps the most far-reaching implication of
folate in the brain is its ability to modify gene expression.
The
folate status is associated with several chronic diseases with a large impact on public health [4].
Material and Methods: After obtaining blood from 141 low-birth-weight infants on the 1st day of life for serum and red cell
folate levels, the infants were randomly allocated into three groups according to the folic acid supplement dose.
Folate is found in many foods, such as legumes (beans, peas, and lentils), sunflower seeds, spinach, asparagus, artichokes, and turnip and collard greens.
"Maternal nutrition during pregnancy can have long-lasting effects on child health, as well as the health of a mother after pregnancy," said the study's principal investigator, Xiaobin Wang, MD, MPH, ScD, from Johns Hopkins University, Baltimore." Our results suggest that adequate maternal
folate may mitigate the effect of a mother's obesity on her child's health."
"Our study shows that germ stem cells in Caenorhabditis elegans are stimulated to divide by a specific
folate that comes from their bacterial diet," said the study's co-senior author Edward Kipreos, a professor in UGA's Franklin College of Arts and Sciences.
Chaudhari et al., "Bacterial
Folates Provide an Exogenous Signal for C.
The report provides comprehensive information on the
Folate Receptor Alpha (Adult
Folate Binding Protein or
Folate Receptor 1 or KB Cells FBP or Ovarian Tumor Associated Antigen MOv18 or FOLR1), targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.
(1) Once called vitamin B9, it is more commonly referred to as
folate (though there are multiple
folates) or folacin.
Take one last week warning that women exposed to too much of the ubiquitous vitamins
folate and B-12 during pregnancy face an increased risk of having an autistic child.
(1) Given that 50% of pregnancies are unplanned, inadequate maternal blood
folate concentrations pose a significant risk to this population as a NTD may occur before a woman even knows that she is pregnant.
Aim of this study was to determine serum iron, serum ferritin and red cell
folate levels among healthy breast fed, fortified milk and cow's milk fed infants.
