antigen

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Related to class I antigens: major histocompatibility complex, MHC, HLA complex
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antigenantigen
  • noun

Words related to antigen

nounany substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies)

Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
T cells possess HLA Class I antigens, whereas B cells possess both Class I and II HLA antigens.
He suggests cancer cells may evade the host immune system by omitting one group of these proteins, called class I antigens, from cell surfaces.
Another approach to the problem is to enhance the immune system's sensitivity to the scarce class I antigens that may be present on malignant cells.
138 unique epitopes were defined for one or a group of two or more intact HLA class I antigens. 110 unique epitopes were defined by using SA beads (Table 1, partial list; complete table in the supplemental information available online at https://doi.org/10.1155/2017/3406230) assays to test eluted alloantibodies that were adsorbed from human sera onto the surface of mammalian rHLA single antigen cells then eluted, and murine monoclonal antibodies to determine specificity of each antibody.
In the present study we tried to improve the efficiency of this assay by enhancing uptake of HLA class I antigens via targeting of endocytic receptors on either monocytes or moDCs.