We are BACK for SEASON FIVE of the pod! In this episode, Dr. Jessica Steier and Dr. Sarah Scheinman discuss Alzheimer's disease and cognitive decline. They cover essential topics including the definition and symptoms of Alzheimer's, the genetic and epigenetic basis of the disease, brain changes associated with Alzheimer's, risk factors such as age, genetics, and lifestyle, modifiable risk factors and prevention strategies, and current treatments and their controversies.
The scientists emphasize that maintaining overall health is crucial for brain health. They recommend a combination of lifestyle choices that promote general well-being, which in turn support cognitive health.
They explore various treatment options, including cholinesterase inhibitors, NMDA receptor antagonists, and monoclonal antibodies targeting amyloid beta. The conversation highlights the ongoing debates about treatment efficacy and the need for further research.
The episode aims to provide valuable insights and alleviate fears surrounding Alzheimer's disease. It concludes with a rapid-fire Q&A segment addressing listeners' questions.

All our sources from this episode are available at: https://www.unbiasedscipod.com/episodes/dont-you-forget-about-me-unraveling-alzheimers

(00:01) Music and Season Five Welcome
(04:30) Introducing Dr. Sarah Scheinman and the Topic of Alzheimer's
(07:49) Understanding Alzheimer's Disease and Its Symptoms
(10:50) The Genetic and Epigenetic Basis of Alzheimer's
(18:23) Risk Factors for Alzheimer's: Age, Genetics, and Lifestyle
(26:02) The Role of Amyloid Plaques and Tau Tangles in Alzheimer's
(30:37) Promoting Early Diagnosis and Intervention for Alzheimer's
(35:21) Breaking Down the Stigma and Building Scientific Literacy
(41:51) Treatments for Alzheimer's Disease
(46:27) Monoclonal Antibodies and Controversy
(53:50) Diagnosing Alzheimer's Disease
(55:32) Final Thoughts: Q&A: Common Questions About Alzheimer's Disease

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