UNLIMITED

The New Age of CRISPR

FromI AM BIO

Start listening View podcast show

UNLIMITED

The New Age of CRISPR

FromI AM BIO

ratings:

Length:

28 minutes

Released:

Apr 11, 2023

Format:

Podcast episode

Description

CRISPR has emerged as a powerful tool for altering DNA sequences with incredible precision, opening up new avenues of research into the treatment of disease. In this episode, we explore the science behind CRISPR, as well as its potential. From curing genetic disorders to creating new crop varieties, the possibilities seem endless. Our four guests today are scientists working to push these gene editing tools to the next frontier.

Released:

Apr 11, 2023

Format:

Podcast episode

Titles in the series (100)

Powerful stories of biotechnology breakthroughs, the people they help, and the global problems they solve. Hosted by BIO President & CEO Dr. Michelle McMurry-Heath.

Skip carousel

UNLIMITED
First Dose: One day before 16-year-old Izzy Thorpe-Wall takes her first dose of Vertex’s stunning Cystic Fibrosis breakthrough, Thorpe and her mother, Clare, open up about their emotional journey and one brave girl’s determination to stay healthy long enough to meet this day of her dreams. Hosted by Jim Greenwood. by I AM BIO
43 min listen
UNLIMITED
COVID-19 Could Generate 1st Computerized Vaccine: Futuristic biotech Moderna is the first to clinically test a coronavirus vaccine, created in weeks using only the virus’ genetic code. The company’s messenger RNA breakthrough may be just in time as a former CDC director warns that animal viruses spilling over to humans is the new normal. Hosted by Jim Greenwood. by I AM BIO
60 min listen
UNLIMITED
Superbuggin’: Incurable gonorrhea and the deadly hospital superbug C. diff offer a frightening window into the gathering public health menace of antibiotic resistance. If society doesn’t wake up and tackle the problem, we could be headed toward a calamity on the magnitude of climate change. Hosted by Jim Greenwood. by I AM BIO
28 min listen
UNLIMITED
“Herd” Immunity: Biotech companies are working feverishly to develop antibody therapies to provide short-term protection against COVID-19. But what if the novel coronavirus mutates and outwits traditional monoclonal antibodies? Well, that’s where the super cows come in. Hosted by Jim Greenwood. by I AM BIO
36 min listen
UNLIMITED
An Alternative to Flying Dirty: While Swedish climate activist Greta Thunberg has kindled a global dialogue about the ravages of climate change and the role of airline emissions, a Colorado biotech is putting forward a jaw-dropping alternative to flight shaming: actual jet fuel with no carbon footprint. Hosted by Jim Greenwood. by I AM BIO
40 min listen
UNLIMITED
Trying our Patients: As genetic sequencing gives scientists new tools to hone in on medical mysteries, Washington politicians flirt dangerously with policies that would stymie the genomic revolution while giving patients scant pricing relief at the pharmacy counter. Hosted by Jim Greenwood. by I AM BIO
36 min listen
UNLIMITED
The Frightening Campaign to Keep Us Unvaccinated: Historic distrust of government institutions, a growing partisan disdain for peer-reviewed science, Russian bots, physical threats against public health officials, and an open spigot of online misinformation and disinformation raise the troubling specter that tens of millions of Americans will forgo COVID vaccination and forestall herd immunity in the United States. Learn how believers in science are uniting to fight back. by I AM BIO
43 min listen
UNLIMITED
The Antibody Test Shortage: Only antibody testing can tell us who has been infected and recovered from coronavirus and when it might be safe to return to work. There’s a massive global shortage of these tests, and a Maryland biotech is racing to bolster the U.S. supply. Hosted by Jim Greenwood. by I AM BIO
27 min listen
UNLIMITED
COVID X-FACTOR: The diversity of our adaptive immune system is why people are reacting so differently to the novel coronavirus. No two people present the virus the exact same way to their immune systems. We’ve evolved in this way as humans to ensure no virus can eradicate our species. Hosted by Jim Greenwood. by I AM BIO
32 min listen
UNLIMITED
Sickle Cell Saviors: Need a dose of inspiration in a time of national tragedy? A remarkable biotech breakthrough from Global Blood Therapeutics offers fresh hope to patients living with sickle-cell disease. Hosted by Jim Greenwood. by I AM BIO
62 min listen
UNLIMITED
Clinical Trials and Tribulations: As Moderna breaks the record for speed in starting the final stage of human testing for its covid vaccine, new BIO CEO Dr. Michelle McMurry-Heath tackles the thorny issue of how to best structure the historic Phase 3 clinical trial. The Boston biotech’s Chief Medical Officer reveals the strategy to test vaccine efficacy on communities of color and others hardest hit by the coronavirus. Hosted by Dr. Michelle McMurry-Heath by I AM BIO
29 min listen
UNLIMITED
What Can Iceland Tell Us About COVID?: The people of Iceland — a country of 360,000 — eagerly volunteered for genetic research on how the coronavirus affects a homogeneous population. Amgen’s work in the Land of Fire and here at home could deliver answers and antibodies to help mitigate the pandemic threat. Hosted by Jim Greenwood. by I AM BIO
32 min listen
UNLIMITED
COVID-19: We Were Warned: For years, leaders on the Bipartisan Commission on Biodefense told Congress and the White House that it wasn’t a matter of if, but when, a pandemic would happen. Exploring the panel’s unheeded recommendations can give the United States a blueprint for what to do going forward to protect us from the coronavirus and future threats. Hosted by Jim Greenwood. by I AM BIO
50 min listen
UNLIMITED
The Other Pandemic: Beating “Nightmare Bugs” (Part 2 of 2): Viral pandemics can lead to secondary bacterial infections that kill millions, Dr. Anthony Fauci concluded after studying the 1918 Spanish flu. A century later, COVID and antibiotic resistance are proving to be a lethal combination. What are the biopharma industry and Congress doing to keep your loved ones safe from superbugs? Hosted by Jim Greenwood. by I AM BIO
32 min listen
UNLIMITED
At Last, COVID Treatments: Covid threatens those whose immune systems can’t make enough neutralizing antibodies to fight off the viral invaders. But what if scientists could make super-potent antibodies in the lab and infuse them into newly infected patients? That’s exactly what the first FDA-authorized coronavirus antibody treatment has achieved. Its maker, Eli Lilly, has generated clinical evidence that their therapy can significantly reduce COVID hospitalization rates when taken early. by I AM BIO
32 min listen
UNLIMITED
A Time to Heal: Joe Biden’s election as 46th President of the United States is a chance to soothe our bitter body politic so we can unite to defeat an enemy that infects and kills without regard to partisan affiliation. by I AM BIO
31 min listen
UNLIMITED
Coronavirus Lung Treatment Could be Ready In Weeks: Regeneron’s rheumatoid arthritis drug shows promise to treat coronavirus-related lung syndrome and stop the inflammation that leads to death. The company also expects to test a preventative antibody shot in June. Hosted by Jim Greenwood. by I AM BIO
40 min listen
UNLIMITED
COVID & the Plastics Problem: Fear and misinformation about how the coronavirus is transmitted has led to dangerous backsliding in society’s efforts to address plastic pollution. But we don’t have to lose this battle to win the COVID war. A Georgia biotech is first to market with a green biopolymer material that looks and feels like plastic but dissolves in ocean water. Hosted by Jim Greenwood. by I AM BIO
32 min listen
UNLIMITED
Biotech’s Finest Hour: As the world waits for biotechnology to deliver COVID-19 treatments and a vaccine, Ambassador Deborah Birx tells BIO’s scientists: “Expectations are high because you’ve delivered for us before and I know that you can deliver for us again.” BIO chairman Jeremy Levin, a biotech pioneer, explains how the industry will rise to meet this moment. Hosted by Jim Greenwood. by I AM BIO
53 min listen
UNLIMITED
Vaccines are a Virtue: As biotech researchers work around the clock on a covid vaccine, ill-informed, anti-science anti-vaxxers must be denounced and excoriated in the public square. BIO’s head of infectious disease policy Phyllis Arthur administers a vital dose of vaccine education, because none of us is safe until we all are. Hosted by Jim Greenwood. by I AM BIO
33 min listen
UNLIMITED
“Herd” Immunity (Redux): Biotech companies are working feverishly to develop antibody therapies to provide short-term protection against COVID-19. But what if the novel coronavirus mutates and outwits traditional monoclonal antibodies? Well, that’s where the super cows come in. Hosted by Jim Greenwood. by I AM BIO
36 min listen
UNLIMITED
COVID-19’s True Origins: There's a joke among ecological health scientists that if “you don’t believe one person can change the world, try eating an undercooked bat.” However, what EcoHealth Alliance’s Dr. William Karesh — a world-renowned expert on zoonotic disease transmission — reveals about the trend line for animal-to-human viral transmission is no laughing matter. Hosted by Jim Greenwood. by I AM BIO
39 min listen
UNLIMITED
Cancer in the COVID Era: Overcrowded hospitals during the pandemic can pose treatment challenges for patients with other serious illnesses. As Kite Pharma CEO Christi Shaw says, “Cancer doesn’t stop in a crisis.” Neither do her company’s employees, who go to extraordinary lengths to get personalized CAR-T treatments to patients around the world. Hosted by Jim Greenwood. by I AM BIO
20 min listen
UNLIMITED
COVID’s Essential Work: The physician-wife of Roivant Sciences CEO Vivek Ramaswamy rushed back to the front lines at the pandemic’s peak — less than a month after giving birth to the couple’s first son. Meanwhile, dad cared for their newborn while testing a promising therapeutic that seeks to overcome deadly cytokine storms caused by the novel coronavirus. Hosted by Jim Greenwood. by I AM BIO
30 min listen
UNLIMITED
Bats Don’t Have Passports: Modernity is plowing new frontiers, bringing us closer to exotic wildlife rich in viruses that our immune systems have not evolved to fight. Preventing future pandemics will require global cooperation, local action and a comprehensive strategy to monitor infectious disease hotspots to reduce the risk of zoonotic disease. Hosted by Jim Greenwood. by I AM BIO
33 min listen
UNLIMITED
Destroying COVID's Genome: Alnylam Pharmaceuticals, which take its name from the center and brightest star in Orion’s Belt, is working on an RNAi therapy to destroy the genome of the novel coronavirus — and with it, its ability to replicate and kill. Hosted by Jim Greenwood. by I AM BIO
39 min listen
UNLIMITED
Going Viral: Vir Biotechnology CEO George Scangos is the scientist selected by his peers to lead the biotechnology industry’s efforts to mitigate and ultimately end the pandemic. He explains how and why the novel coronavirus is so contagious and potentially dangerous to millions. Hosted by Jim Greenwood. by I AM BIO
23 min listen
UNLIMITED
Biotech's Finest Hour (Redux): As the world waits for biotechnology to deliver COVID-19 treatments and a vaccine, Ambassador Deborah Birx tells BIO’s scientists: “Expectations are high because you’ve delivered for us before and I know that you can deliver for us again.” BIO chairman Jeremy Levin, a biotech pioneer, explains how the industry will rise to meet this moment. Hosted by Jim Greenwood. by I AM BIO
48 min listen
UNLIMITED
Vaccine Velocity: How can global nonprofits like the Center for Epidemic Preparedness Innovations (CEPI) deliver a safe and effective vaccine against the novel coronavirus in just 12 to 18 months when the world record for vaccine approval is four years? CEPI CEO Richard Hatchett, a 9/11 hero, says it’s all about smart planning. By the time governments give the green light on the safety and efficacy of a covid vaccine, manufacturer capacity will be pre-scaled up and able to quickly churn out doses by the tens or hundreds of millions. Hosted by Jim Greenwood. by I AM BIO
33 min listen
UNLIMITED
COVID-19’s True Origins (Redux): There's a joke among ecological health scientists that if “you don’t believe one person can change the world, try eating an undercooked bat.” However, what EcoHealth Alliance’s Dr. William Karesh — a world-renowned expert on zoonotic disease transmission — reveals about the trend line for animal-to-human viral transmission is no laughing matter. Hosted by Jim Greenwood. by I AM BIO
39 min listen

More Episodes from I AM BIO

Skip carousel

UNLIMITED
The Faceless Middleman Between You and Your Doctor: A troubling disconnect between medical expertise and insurance mandates is putting patients' health at risk. Policies like step therapy and prior authorization are forcing individuals into treatments not recommended by their doctors—often with devastating consequences. In this episode, we hear from a patient who endured months of suffering due to her insurer's 'fail-first' requirements. We also talk with a doctor navigating this impossible system and a biotech leader fighting to ensure innovative treatments reach the patients who need them most. Follow us on LinkedIn, X, Facebook and Instagram. Visit us at https://www.bio.org/ by I AM BIO
27 min listen
UNLIMITED
The Horseshoe Crab Saved Us. Can We Save the Horseshoe Crab? (REDUX): The horseshoe crab has endured for over 450 million years. It has survived several mass extinctions including the one that killed off the dinosaurs. One reason for their incredible resiliency is their ability to fend off bacterial infection. Their blood contains cells that clot around invading bacteria, thereby protecting them from the attacking toxins. In this episode we talk with three experts about how this animal’s unique blue blood has become essential to modern medicine. We also talk about why horseshoe crab populations are dwindling, and what biotech is doing to address the shortfall. by I AM BIO
28 min listen
UNLIMITED
How Love Combined with Science Leads to Hope for Rare Disease: There are over 7000 rare diseases identified in the U.S. alone. Many of these diseases affect children, leaving families desperate for answers. In this episode, we talk with one of those families and the biotech company offering them new hope. We also talk with an expert on policy that has jump-started R&D for rare diseases. by I AM BIO
27 min listen
UNLIMITED
How Will We Secure our Food Future?: As the global population approaches 10 billion by 2050, the challenge of providing safe, nutritious food is growing more urgent. Climate change is further straining food systems, impacting water availability, crop yields, and livestock health. In this episode, two experts discuss innovative biotech solutions aimed at addressing these pressing issues, offering hope for a sustainable path forward in feeding the world. by I AM BIO
26 min listen
UNLIMITED
Biotechnology is a National Security Asset: Since Watson and Crick discovered DNA's double helix structure in 1953, the US has been a leader in biotechnology innovation. American excellence in this field has greatly benefited people around the world. In this episode, we talk about why this leadership position may be threatened and why that matters to our national security. by I AM BIO
27 min listen
UNLIMITED
A Doctor Fights to Save His Own Life: The David Fajgenbaum Story.: David Fajgenbaum was in his third year of medical school when he was diagnosed with a rare and life-threatening disease that began shutting down his organs, bringing him perilously close to death. Although he survived the initial episode, he faced four additional relapses, each pushing him to the brink of death. In this episode, we speak with David about his relentless journey to discover the treatment that ultimately put his disease into remission. We also explore how his personal battle inspired the creation of a groundbreaking approach to help others suffering from rare diseases. by I AM BIO
22 min listen
UNLIMITED
What We Know About the Microbiome (REDUX): The gut microbiome, which consists of trillions of bacteria, viruses, and fungi, plays a crucial role in our health. However, there is still much to learn about this complex ecosystem. On this episode we talk with experts who tell us where the science is—how much we know, and how much we don’t. Two companies, Bloom Science and Seres Therapeutics, are leveraging the microbiome to develop new therapeutics. The potential of the microbiome is vast, and further research and technological advancements will continue to unlock its benefits. by I AM BIO
27 min listen
UNLIMITED
Is CRISPR the New Sickle Cell Savior? (REDUX): 2023 ended with an exciting biotech breakthrough for sickle cell patients. A gene-editing therapy using the revolutionary CRISPR technology provides new hope and options for the nearly 100,000 Americans with sickle cell disease. In this episode, we talk with the company behind one of the life-changing therapies, CASGEVY, and speak with two advocates for sickle cell patients. by I AM BIO
25 min listen
UNLIMITED
Listener takeover: Your Biotech Questions Answered: YOU asked, and we answered. In this episode, we had our experts on standby to answer questions from you, our listeners. We discuss topics ranging from the safety of genetically modified foods (GMOs), to the new era of personalized medicine, feeding the world by 2050, and even what makes start-up companies attractive to investors. by I AM BIO
21 min listen
UNLIMITED
Editing Cells Within the Body—a New CRISPR Frontier: With its potential to expand the horizons of what’s possible for patients, CRISPR is the new darling of biotech. Reaching an important milestone in 2023 with the FDA approval of a sickle cell treatment using CRISPR, the technology is poised to break new barriers for treating patients in the near future. In this episode we talk with two companies working together on the next generation of CRISPR: editing cells within the body. We discuss the progress and the challenge in making this breakthrough a reality. by I AM BIO
21 min listen
UNLIMITED
Biotech is Climate Tech: Biotech companies are addressing climate change through innovation—from carbon neutral facilities to agricultural innovations to reduce greenhouse gas emissions. BIO was on the ground at the COP28 UN Climate Change Conference in Dubai to deliver the message that biotech is climate tech. by I AM BIO
21 min listen
UNLIMITED
Biotech for our Pets: More than half of U.S. households include pets, but there has been a lack of medical treatments developed specifically for small animals. Biotech companies are working to change that with new treatment options that both borrow from and, potentially, advance human health discoveries. by I AM BIO
28 min listen
UNLIMITED
What We Know About the Microbiome: The gut microbiome, which consists of trillions of bacteria, viruses, and fungi, plays a crucial role in our health. However, there is still much to learn about this complex ecosystem. On this episode we talk with experts who tell us where the science is—how much we know, and how much we don’t. Two companies, Bloom Science and Seres Therapeutics, are leveraging the microbiome to develop new therapeutics. The potential of the microbiome is vast, and further research and technological advancements will continue to unlock its benefits. by I AM BIO
27 min listen
UNLIMITED
Is CRISPR the New Sickle Cell Savior?: 2023 ended with an exciting biotech breakthrough for sickle cell patients. A gene-editing therapy using the revolutionary CRISPR technology provides new hope and options for the nearly 100,000 Americans with sickle cell disease. In this episode, we talk with the company behind one of the life-changing therapies, CASGEVY, and speak with two advocates for sickle cell patients. by I AM BIO
25 min listen
UNLIMITED
“On My Own”—Desperate to Stop a Resistant Bacterial Infection (REDUX): Bradley Burnam woke up one morning, looked in the mirror and found one ear twice it’s normal size and his face swollen and discolored. He would spend the next several years in and out of the hospital fighting a relentless infection that would not respond to available treatments. The experience took him from patient to mad scientist, to biotech company founder. In this episode, Bradley takes us through his desperate journey to find a cure. We also talk with the leader of an organization helping to get more antimicrobials to the marketplace. by I AM BIO
28 min listen
UNLIMITED
The Synbio Revolution is Here (REDUX): Innovative companies are using synthetic biology to engineer organisms and create new materials that could transform every sector of our economy, from health care to food and energy production. Those companies say we’ve entered a synbio revolution, and it holds potential to improve the health of people and our planet. In this episode, we talk with three synbio experts about how this convergence of genetic engineering, computer science and other scientific disciplines is making our world more sustainable. by I AM BIO
26 min listen
UNLIMITED
How Biotechs Survive the Valley of Death (REDUX): For biotech companies, the valley of death describes the difficult path from initial discovery to FDA approval and commercialization. It's a treacherous journey—one that even promising innovations often don't complete. Adequate funding, regulatory hurdles and the immense complexity of the biotech landscape are among the never-ending challenges faced by early stage biotechs. In this episode we talk with two biotech executives about what it’s like to struggle and survive in this rough-and-tumble industry. by I AM BIO
25 min listen
UNLIMITED
Biotech Women Striking at the Glass Ceiling (REDUX): The biotech industry offers unique opportunities for women to advance as executives and entrepreneurs. There are headwinds, however, including unequal access to venture capital. In this episode, we talk with three executives who are part of a wave of women-led companies in biotech. Our guests speak to why women’s leadership matters and the barriers that remain to breaking the glass ceiling. They also tell us about a new networking initiative—the biotech sisterhood—to catalyze women’s success in corporate leadership and mentor the next generation of women executives. by I AM BIO
25 min listen
UNLIMITED
The Horseshoe Crab Saved Us. Can We Save the Horseshoe Crab? (REDUX): The horseshoe crab has endured for over 450 million years. It has survived several mass extinctions including the one that killed off the dinosaurs. One reason for their incredible resiliency is their ability to fend off bacterial infection. Their blood contains cells that clot around invading bacteria, thereby protecting them from the attacking toxins. In this episode we talk with three experts about how this animal’s unique blue blood has become essential to modern medicine. We also talk about why horseshoe crab populations are dwindling, and what biotech is doing to address the shortfall. by I AM BIO
28 min listen
UNLIMITED
“On My Own”—Desperate to Stop a Resistant Bacterial Infection: Bradley Burnam woke up one morning, looked in the mirror and found one ear twice it’s normal size and his face swollen and discolored. He would spend the next several years in and out of the hospital fighting a relentless infection that would not respond to available treatments. The experience took him from patient to mad scientist, to biotech company founder. In this episode, Bradley takes us through his desperate journey to find a cure. We also talk with the leader of an organization helping to get more antimicrobials to the marketplace. by I AM BIO
28 min listen
UNLIMITED
The Synbio Revolution is Here: Innovative companies are using synthetic biology to engineer organisms and create new materials that could transform every sector of our economy, from health care to food and energy production. Those companies say we’ve entered a synbio revolution, and it holds potential to improve the health of people and our planet. In this episode, we talk with three synbio experts about how this convergence of genetic engineering, computer science and other scientific disciplines is making our world more sustainable. by I AM BIO
26 min listen
UNLIMITED
How Biotechs Survive the Valley of Death: For biotech companies, the valley of death describes the difficult path from initial discovery to FDA approval and commercialization. It's a treacherous journey—one that even promising innovations often don't complete. Adequate funding, regulatory hurdles and the immense complexity of the biotech landscape are among the never-ending challenges faced by early stage biotechs. In this episode we talk with two biotech executives about what it’s like to struggle and survive in this rough-and-tumble industry. by I AM BIO
25 min listen
UNLIMITED
Biotech Women Striking at the Glass Ceiling: The biotech industry offers unique opportunities for women to advance as executives and entrepreneurs. There are headwinds, however, including unequal access to venture capital. In this episode, we talk with three executives who are part of a wave of women-led companies in biotech. Our guests speak to why women’s leadership matters and the barriers that remain to breaking the glass ceiling. They also tell us about a new networking initiative—the biotech sisterhood—to catalyze women’s success in corporate leadership and mentor the next generation of women executives. by I AM BIO
25 min listen
UNLIMITED
We Need Bees. Bees Need Biotech.: Bees and other pollinators are critical to our survival, with one out of every three bites of food we eat depending on pollination to produce. That’s why reports of a decline in bee populations and rising threats from pests, viruses and environmental pressures, including climate change, are alarming. In this episode we talk with an expert on bees and other pollinators about how bees are doing and why it’s important to save them. We also talk with two biotech leaders whose companies are working to improve bee health through development of innovative treatments for some of the worst threats faced by bees. by I AM BIO
27 min listen
UNLIMITED
The Horseshoe Crab Saved Us. Can We Save the Horseshoe Crab?: The horseshoe crab has endured for over 450 million years. It has survived several mass extinctions including the one that killed off the dinosaurs. One reason for their incredible resiliency is their ability to fend off bacterial infection. Their blood contains cells that clot around invading bacteria, thereby protecting them from the attacking toxins. In this episode we talk with three experts about how this animal’s unique blue blood has become essential to modern medicine. We also talk about why horseshoe crab populations are dwindling, and what biotech is doing to address the shortfall. by I AM BIO
28 min listen
UNLIMITED
Stand Up for Science—The Fight Against Misinformation (Redux): Wading through the torrent of information available online is challenging for everyone. It can be hard to know what and whom to believe. We talk with the FDA Commissioner and other leaders on the frontlines of health and science about how to be more aware of false and misleading information, and its risks to our wellbeing and future innovation. And we discuss ways to stand up for science and stop the spread of misinformation. by I AM BIO
26 min listen
UNLIMITED
Is Space the Next Frontier for Biotech? (Redux): The International Space Station has been orbiting in lower earth since 1998 and has been continually inhabited since November 2000. The ISS was originally conceived as a staging base for future missions into deep space. As it turns out, lower earth orbit is an ideal setting for scientific research, from physics and meteorology to astronomy and the life sciences. In this episode we talk with three scientists whose projects are using lower earth orbit to deepen our knowledge of biotechnology and its benefits for mankind. by I AM BIO
27 min listen
UNLIMITED
The New Age of CRISPR (Redux): CRISPR has emerged as a powerful tool for altering DNA sequences with incredible precision, opening up new avenues of research into the treatment of disease. In this episode, we explore the science behind CRISPR, as well as its potential. From curing genetic disorders to creating new crop varieties, the possibilities seem endless. Our four guests today are scientists working to push these gene editing tools to the next frontier. by I AM BIO
28 min listen
UNLIMITED
Accelerating Hope: The Pathway for Cures (Redux): When people were dying from AIDS in the 1980s and 90s, Congress found a way to expedite the drug approval process and saved countless lives. Established in 1992, the Accelerated Approval Program allows the FDA to speed approval of drugs for patients with serious and life-threatening conditions. In this episode we talk with the father of children with a rare disease, a company CEO working to treat rare diseases and two policy experts on Accelerated Approval. by I AM BIO
23 min listen

Related podcast episodes

Skip carousel

UNLIMITED
Stephanie Cherqui Discusses Clinical Development of CRISPR Therapies for Rare Diseases by CRISPR Cuts
20 min listen
UNLIMITED
Why AI and Biotech are BFFs (Redux): The convergence of Artificial Intelligence (AI) and biotechnology has emerged as one of the most exciting and transformative areas of science. Researchers are developing new tools and technology that could bring about breakthroughs to revolutionize the fields of medicine and health care. In this episode, we talk with scientists who are using AI to unlock new possibilities in the search for novel drugs, cures, and treatments. by I AM BIO
22 min listen
UNLIMITED
Sunil Sharma and Raffaella Soldi Talk CRISPR For Unbiased Drug Screening for Rare Pediatric Cancers: Dr. Sunil Sharma and Dr. Raffaella Soldi of the Translational Genomics Research Institute chat about using CRISPR arrayed screens to identify novel drug targets for Ewing's Sarcoma, outlooks for the future of cancer therapies, and the Arizona heat. by CRISPR Cuts
25 min listen
UNLIMITED
Accelerating Hope: The Pathway for Cures: When people were dying from AIDS in the 1980s and 90s, Congress found a way to expedite the drug approval process and saved countless lives. Established in 1992, the Accelerated Approval Program allows the FDA to speed approval of drugs for patients with serious and life-threatening conditions. In this episode we talk with the father of children with a rare disease, a company CEO working to treat rare diseases and two policy experts on Accelerated Approval. by I AM BIO
23 min listen
UNLIMITED
A gene’s-eye view: Useful tool or narrow lens? (Ep 73) by Big Biology
87 min listen
UNLIMITED
Proteomics and Deep Learning with Melih Yilmaz by Axial Podcast
69 min listen
UNLIMITED
Why AI and Biotech are BFFs: The convergence of Artificial Intelligence (AI) and biotechnology has emerged as one of the most exciting and transformative areas of science. Researchers are developing new tools and technology that could bring about breakthroughs to revolutionize the fields of medicine and health care. In this episode, we talk with scientists who are using AI to unlock new possibilities in the search for novel drugs, cures, and treatments. by I AM BIO
22 min listen
UNLIMITED
Bryce Olson Relays His Experience on Personalized Therapies for Cancer Patients: After being diagnosed with aggressive prostate cancer, Bryce Olson quickly learned the science behind it and has leveraged NGS to understand his tumor genomics and find opportunities in personalized therapies. Hear the patient perspective for the first t... by CRISPR Cuts
43 min listen
UNLIMITED
627: Sorting Out the Science of Fruit Fly Flight and Behavior - Dr. Michael Dickinson: Dr. Michael Dickinson is the Esther M. and Abe M. Zarem Professor of Bioengineering at the California Institute of Technology. His work focuses on the biomechanics and the biophysics of life with a particular focus on how animals fly. He... by People Behind the Science Podcast Stories from Scientists about Science, Life, Research, and Science Careers
45 min listen
UNLIMITED
Nessa Carey and Xand Van Tulleken on How Gene Editing Will Rewrite Our Futures: In this week's episode of the Intelligence Squared podcast we were joined by Nessa Carey, the molecular biologist and author of Hacking The Code Of Life. She was interviewed by the doctor and TV presenter Xand Van Tulleken in a wide-rangi... by Intelligence Squared
65 min listen
UNLIMITED
Spotlight on CRISPR (Neurology Recall Special Report): Spotlight on CRISPR (Neurology Recall Special Report) by Neurology® Podcast
49 min listen
UNLIMITED
Gene Hack, Man: ENCORE Computers and DNA have a few things in common. Both use digital codes and are prone to viruses. And, it seems, both can be hacked. From restoring the flavor of tomatoes to hacking into the president’s DNA, discover the promise and... by Big Picture Science
54 min listen
UNLIMITED
Dr. Vera Gorbunova — Applying Lessons From Long-Living Animals to Combat Human Aging by Longevity by Design
34 min listen
UNLIMITED
You Can't Handle the Tooth: Hardened plaque harvested from Neanderthal teeth is loaded with genetic material from plants and animals these prehistoric hominins ate, as well as remnants of microbes that reveal a surprising amount about how they lived and even what made them sick. Re by We Have Concerns
21 min listen
UNLIMITED
Is CRISPR the New Sickle Cell Savior?: 2023 ended with an exciting biotech breakthrough for sickle cell patients. A gene-editing therapy using the revolutionary CRISPR technology provides new hope and options for the nearly 100,000 Americans with sickle cell disease. In this episode, we talk with the company behind one of the life-changing therapies, CASGEVY, and speak with two advocates for sickle cell patients. by I AM BIO
25 min listen
UNLIMITED
Dr. George Church—Gene Therapy and Aging by Longevity by Design
29 min listen
UNLIMITED
Ep. 232: “Neurodegenerative Diseases” Featuring Dr. Clive Svendsen: Dr. Clive Svendsen is the Executive Director of the Regenerative Medicine Institute at Cedars-Sinai. His lab uses stem cells to develop models and treatments for neurodegenerative diseases. He talks about using stem cells to model spinal muscular atrop... by The Stem Cell Podcast
75 min listen
UNLIMITED
Dr. Haim Cohen — The Protective Role of SIRT6 on Aging and Longevity by Longevity by Design
43 min listen
UNLIMITED
Crowding, Braces, and Sleep—Sandra Kahn and Paul Ehrlich—Jaws: The Story of a Hidden Epidemic: What do braces or crowding in the mouth have to do with sleep? At first, you may think there’s no connection, but according to Sandra Kahn, Paul Ehrlich, and a growing body of research, they’re directly related. Kahn and Ehrlich join the podcast... by Finding Genius Podcast
53 min listen
UNLIMITED
Episode 52. Neurological Disorders: Sara Manning Peskin: The brain is the most mysterious and complex organ of the body, and when things go awry, we may be confronted with personal tragedy and we may gain insights on what it means to be human. With us to discuss neurological disorders and the history of... by Science History Podcast
78 min listen
UNLIMITED
Dr. Ronald Krauss—A Proactive Approach to Heart Health by Longevity by Design
54 min listen
UNLIMITED
Disruptive Innovation in the Era of Big Tech by HBR On Strategy
48 min listen
UNLIMITED
Heidi J. Larson, "Stuck: How Vaccine Rumors Start--and Why They Don't Go Away" (Oxford UP, 2020): An interview with Heidi J. Larson by New Books in the History of Science
50 min listen
UNLIMITED
Dr. Andrew Huberman — How The Gut Microbiome, Sleep, and Sunlight Impact The Brain by Longevity by Design
61 min listen
UNLIMITED
Eric Schmidt by Theory and Practice
47 min listen
UNLIMITED
The amphibian omnivore’s dilemma: Plasticity-led evolution in spadefoot tadpoles (Ep 78) by Big Biology
63 min listen
UNLIMITED
Prime Minister Jacinda Ardern: Can we work together to end violent extremism online?: New Zealand Prime Minister Jacinda Ardern is determined to stop the spread of extremism and radicalization online. In the aftermath of the 2019 terrorist attack on two mosques in Christchurch, she saw the livestream of the tragedy go viral across social media feeds, including her own. In response, she led the creation of the Christchurch Call, a commitment by governments and tech companies to eliminate terrorist and violent extremist content online. In this episode, Brad and Prime Minister Ardern discuss the Christchurch Call, how algorithms fan the flames of extremism and the need to address misinformation to create a stronger, more connected society. by Tools and Weapons with Brad Smith
24 min listen
UNLIMITED
105. Jennifer Doudna (Geneticist) - Intelligent Redesign?: Spontaneous talk on surprise topics. Geneticist Jennifer Doudna on the profound implications of her CRISPR-Cas-9 gene editing technology for the future of humanity. by Think Again - a Big Think Podcast
56 min listen
UNLIMITED
Steven Johnson wants to know how enlightenment happens: It’s official, the TED Interview has a new host! In Chris’s last episode as head of the show, he interviews his successor, bestselling science and technology author Steven Johnson. by The TED Interview
55 min listen
UNLIMITED
S4E21 Exploratory Structural Equation Modeling by Quantitude
44 min listen

Discover this podcast and so much more

The New Age of CRISPR

The New Age of CRISPR

Description

Titles in the series (100)

More Episodes from I AM BIO

Related podcast episodes