Ezetimibe /ɛˈzɛtᵻmɪb/ is a drug that lowers plasma cholesterol levels. It acts by decreasing cholesterol absorption in the small intestine. It may be used alone (marketed as Zetia or Ezetrol), when other cholesterol-lowering medications are not tolerated, or together with statins (e.g., ezetimibe/simvastatin, marketed as Vytorin and Inegy) when statins alone do not control cholesterol.
Ezetimibe is recommended as second line therapy for those intolerant of statins or unable to achieve target LDL cholesterol levels on statins alone by several major medical group practice guidelines, but not by those of the American Heart Association and American College of Cardiology.
As of mid-2014, treatment guidelines of the American Heart Association/American College of Cardiology recommend that people with dyslipidemia be treated with a statin. These guidelines recommend increasing the statin dose in certain populations, but do not recognize target serum cholesterol levels or recommend the use of non-statin cholesterol lowering drugs. Guidelines issued by the European Society of Cardiology/European Atherosclerosis Society, the Japan Atherosclerosis Society, the National Institute for Health and Clinical Excellence, and the International Atherosclerosis Society recommend ezetimibe as one of several second line treatment options for people who are intolerant of statins or who are unable to reach serum LDL goals using statins alone.
There's a voice inside our soul
Calling out so we don't fall
Nothing's lost that can't be found
Ain't a thing you can't get 'round
Turn it into something good
There's a chance you really could
Turn it into something special
When you see it's time to choose
Gonna find you'll never lose
Turn it into something special
When your calm is broken too
And you don't know what to do
Hold your fire and look above
Take the flame don't put it out
Turn it into something good
There's a chance you really could
Turn it into something special
When you see it's time to choose
Gonna find you'll never lose
Turn it into something special
Just believe in something new
We all have our part to do
Turn it into something special
And you'd still be standing strong
Hold your crown and carry on
Turn it into something special
When you know right from the start
Gonna play it from the heart
Take a chance and make things better
Leave the fears and doubts behind
Don't give in just keep on tryin'
Turn it into something special
Mmmmm. mmmmm... uuuuuu...
Turn it into something good
There's a chance you really could
Turn it into something special
When you see it's time to choose
Gonna find you'll never lose
Turn it into something special
Turn it into something new
We all have our part to do
take a chance and make it special
And you'd still be standing strong
Hold your crown and carry on
Turn it into something...
Just believe in something
Naa naa naa na na naa.
Just believe in something, yea yea.
Naa naa naa na na naa.
We gotta carry on, we gotta carry on and on.
Naa naa naa na na naa.
Oo oo oo ooooo.
You gotta believe in something
Naa naa naa na na naa...