ZAP70 deficiency
ZAP70 deficiency, or zeta-chain-associated protein 70 kD deficiency, is a rare autosomal recessive form of severe combined immunodeficiency (SCID).
It is associated with ZAP70.
Presentation
It is characterized by a lack of CD8+ T cells and the presence of circulating CD4+ T cells which are unresponsive to T-cell receptor (TCR)-mediated stimuli.
Treatment
No cure currently exists; however, gene therapy has been proposed.
References
External links
This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/ZAP70_deficiency
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