Bark is a municipality in the district of Segeberg, in Schleswig-Holstein, Germany.
The Sonic the Hedgehog video game franchise began in 1991 with the game Sonic the Hedgehog for the Sega Genesis, which pitted a blue anthropomorphic hedgehog named Sonic against a rotund human man named Doctor Eggman (or Doctor Ivo Robotnik). The sequel, Sonic 2, gave Sonic a fox friend named Tails. Shortly afterward, Sonic CD introduced Amy Rose, a female hedgehog with a persistent crush on Sonic, and Sonic 3 introduced Knuckles the Echidna, Sonic's rival and, later, friend. All five of these have remained major characters and appeared in dozens of games.
The series has introduced dozens of additional recurring characters over the years. These have ranged from anthropomorphic animal characters like Shadow the Hedgehog and Cream the Rabbit to robots created by Eggman like Metal Sonic and E-123 Omega, as well as human characters like Eggman's grandfather Gerald Robotnik. The series also features two fictional species: Chao, which have usually functioned as digital pets and minor gameplay and plot elements, and Wisps, which have been used as power-ups.
A barque, barc, or bark is a type of sailing vessel with three or more masts having the fore- and mainmasts rigged square and only the mizzen (the aftermost mast) rigged fore-and-aft.
The word barque entered English via French, which in turn came from the Latin barca by way of Occitan, Spanish or Italian. The Latin barca may stem from Celtic "barc" (per Thurneysen) or Greek "baris" (per Diez), a term for an Egyptian boat. The Oxford English Dictionary considers the latter improbable.
In the 18th century, the British Royal Navy used the term bark for a nondescript vessel that did not fit any of its usual categories. Thus, when the British Admiralty purchased a collier for use by James Cook in his journey of exploration, she was registered as HM Bark Endeavour to distinguish her from another Endeavour, a sloop already in service at the time. She happened to be a ship-rigged sailing vessel with a plain bluff bow and a full stern with windows.
William Falconer's Dictionary of the Marine defined "bark", as "A general name given to small ships: it is however peculiarly appropriated by seamen to those which carry three masts without a mizzen topsail. Our Northern Mariners, who are trained in the coal-trade, apply this distinction to a broad-sterned ship, which carries no ornamental figure on the stem or prow."
Rap GTP-binding protein also known as Ras-related proteins or simply RAP is a type of small GTPase, similar in structure to Ras.
These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. RAP counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner.
Human genes that encode Ras-related proteins include:
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
Rap may refer to:
Rap may refer to:
Rapper may refer to:
RAP may refer to:
RAP was a Dutch football (soccer) club based in Amsterdam, Netherlands, that played in the Netherlands Football League Championship. The club played from 1887 to 1914, and were the first official football champion of the Netherlands ever in the 1899 season. (The unofficial winner of the first edition in 1888-1889 was won by VV Concordia from Rotterdam).
Founded in Amsterdam, on November 14, 1887 a football club was formed from members of three cricket clubs, R.U.N., Amstels and Progress: RAP. The team managed to win the Netherlands Football League Championship five times, and were undefeated in the 1898-99 season. The dominance of R.A.P. in that season was demonstrated by the fact that HVV Den Haag, who finished second that year, were eight points behind R.A.P. in the end. Furthermore, they won the De Telegraaf Cup in 1898-99 for the first time, making R.A.P. the first team in the Netherlands to win the League title and the Cup in the same season.
In 1900-1901 they finished fourth place, followed by a fifth-place finish in 1901-1902. in 1902-03 RAP hit rock bottom and finished last in the league, forcing them to play in a relegation playoff series, which they won, very narrowly escaping relegation. A few years later the club would eventually be relegated to the second division anyway.