Ydc2 protein domain

In molecular biology, the protein domain, Ydc2 (also known as SpCce1), is a Holliday junction resolvase from the fission yeast Schizosaccharomyces pombe that is involved in the maintenance of mitochondrial DNA.

Function

In molecular biology, the Ydc2 domains are enzymes, or in other words biological catalysts, capable of resolving Holliday junctions into separate DNA duplexes by cleaving DNA after 5'-CT-3, and 5'-TT-3, sequences.

Properties

The junction resolving enzymes are very diverse, but have the following properties in common:

Essentially, they are highly specific.

Limiting factors

Furthermore, the cleavage efficiency is affected by:

Structure

This protein domain forms a ribonuclease H fold consisting of two beta sheets and one alpha helix, arranged as a beta-alpha-beta motif. Each beta sheet has five strands, arranged in a 32145 order, with the second strand being antiparallel to the rest.

Youth detention center

In American criminal justice systems a youth detention center, also known as a juvenile detention center (JDC),juvenile hall or, more colloquially as juvy, is a secure prison or jail for young people, often termed juvenile delinquents, awaiting court hearings and/or placement in long-term care facilities and programs. Juveniles go through a separate court system, the juvenile court, which sentences or commits juveniles to a certain program or facility.

Overview

Once processed in the juvenile court system there are many different pathways for juveniles. Whereas some juveniles are released directly back into the community to undergo community-based rehabilitative programs, some juveniles may pose a greater threat to society and to themselves and therefore are in need of a stay in a supervised juvenile detention center. If a juvenile is sent by the courts to a juvenile detention center there are two types of facilities: secure detention and secure confinement.

Secure detention means that juveniles are held for usually short periods of time in facilities in order to await current trial hearings and further placement decisions. By holding juveniles in secure detention, it ensures appearance in court while also keeping the community safe and risk-free of the juvenile. This type of facility is usually called a "juvenile hall," which is a holding center for juvenile delinquents. On the other hand, secure confinement implies that the juvenile has been committed by the court into the custody of a secure juvenile correctional facility for the duration of a specific program, which can span from a few months to many years.