XXXX may refer to:
Music
XXXX syndrome (also called tetrasomy X, quadruple X, or 48, XXXX) is a rare chromosomal disorder caused by the presence of four X chromosomes instead of two X chromosomes. This condition occurs only in females, as there are no Y chromosomes present. Tetrasomy X was first described in 1961, and since then approximately 100 cases have been reported worldwide. Approximately 60 females have been described in medical literature with this condition.
Tetrasomy X is a chromosomal aneuploidy, meaning it arises from a defect in meiosis. This can occur when homologous X chromosomes fail to separate in the formation of the egg or sperm. Tetrasomy X is usually suspected based on symptoms present in the individual and is confirmed via karyotyping, which reveals the extra X chromosomes.
Symptoms of tetrasomy X are highly variable, ranging from relatively mild to severe. Symptoms are often similar to those of trisomy X. Physically, tetrasomy X patients tend to have distinctive facial features such as epicanthal folds, flat nasal bridges, upslanting palpebral fissures, midface hypoplasia, small mouths, cleft or high arched palates, delayed or absent teeth, or enamel defects. The majority have also been reported as being longer and taller. Many also show joint and muscle tone abnormalities, including hypotonia and joint looseness in the hips. Skeletal problems may also be present, including abnormal curvatures of the spine. An informal study conducted by Tetrasomy & Pentasomy X Syndrome Information and Support found that 10% of girls had joint laxity in the hips and 20% had joint limitations in a sample size of 20 tetrasomy and pentasomy patients.
A speaking clock or talking clock is a live or recorded human voice service, usually accessed by telephone, that gives the correct time. The first telephone speaking clock service was introduced in France, in association with the Paris Observatory, on 14 February 1933.
The format of the service is similar to that of radio time signal services. At set intervals (e.g. ten seconds) a voice announces (for example) "At the third stroke, the time will be twelve forty-six and ten seconds...", with three beeps following. Some countries have sponsored time announcements and include the sponsor's name in the message.
In 1995, the ASEAN has set up nine speaking clocks.
Loss may refer to:
Loss is the debut album of Scottish indie pop band Mull Historical Society. It includes the singles "Barcode Bypass", "I Tried", "Animal Cannabus" and "Watching Xanadu". The album reached number 43 in the UK album chart. It was inspired by the sudden death of his father in 1999 and his upbringing on the Isle of Mull. It contains samples from a Caledonian MacBrayne ferry and the waves on Calgary Bay in Mull. "Barcode Bypass" is about a small shopkeeper threatened by the supermarkets, and "Watching Xanadu" is about watching the film Xanadu.
All songs written and composed by Colin MacIntyre.
The CD version of the album was released as an enhanced CD-ROM containing footage of Colin MacIntyre performing live acoustic versions of the songs "Barcode Bypass" and "I Tried".
In baseball and softball, a pitcher's win–loss record (also referred to simply as their record) indicates the number of wins (denoted "W") and losses (denoted "L") they have been credited with. For example, a 20–10 win–loss record would represent 20 wins and 10 losses.
In each game, one pitcher on the winning team is awarded a win (the "winning pitcher") and one pitcher on the losing team is given a loss (the "losing pitcher") in their respective statistics. These pitchers are collectively known as the pitchers of record. The designation of win or loss for a pitcher is known as a decision, and only one pitcher for each team receives a decision. A starting pitcher who does not receive credit for a win or loss is said to have no decision. In certain situations, another pitcher on the winning team who pitched in relief of the winning pitcher can be credited with a save, and holds can be awarded to relief pitchers on both sides, but these are never awarded to the same pitcher who is awarded the win.