XPO

XPO may refer to:

XPO6

Exportin-6 is a protein that in humans is encoded by the XPO6 gene.

Exportins, such as XPO6, recruit cargo in the nucleoplasm in the presence of RAN (MIM 601179)-GTP and form ternary export complexes. These complexes are transported through nuclear pore complexes to the cytoplasm, where GTP is hydrolyzed and the export complex is disassembled.[supplied by OMIM]

References

Further reading

XPO5

Exportin-5 is a protein that in humans is encoded by the XPO5 gene.

Exportin-5 belongs to a large family of karyopherins (see MIM 602738) that mediate the transport of proteins and other cargo between the nuclear and cytoplasmic compartments.[supplied by OMIM]

Interactions

XPO5 has been shown to interact with ILF3 and Ran (biology).

References

Further reading