WTAP-TV is the NBC-affiliated television station for the Mid-Ohio Valley that is licensed to Parkersburg, West Virginia. It broadcasts a high definition digital signal on UHF channel 49 (or virtual channel 15.1 via PSIP) from a transmitter in Independence Township, Ohio. The station can also be seen on Suddenlink channel 4 and CAS Cable channel 7. There's a high definition feed offered on Suddenlink digital channel 104 and CAS Cable digital channel 384. Owned by Gray Television, WTAP is sister to low-powered Fox affiliate WOVA-LD and low-powered CBS outlet WIYE-LD. The three television stations share studios on Market Street (official address is One Television Plaza) in downtown Parkersburg. Syndicated programming on WTAP includes Wheel of Fortune, Jeopardy!, Inside Edition and Dr. Phil among others.
The station signed-on Veterans Day 1953. It was the first television station to launch in North-Central West Virginia. WTAP aired an analog signal on UHF channel 15 and, early in its life, aired programming from all three major networks of the time—NBC, ABC and CBS—but, then as now, was a primary NBC affiliate. WJPB-TV in Fairmont (channel 35, now WDTV on channel 5) would launch four months later and take on exactly the same affiliation. Original plans called for WTAP to join WJPB and turn North-Central West Virginia into one giant television market. However, the area is a very rugged dissected plateau and neither station's signal was strong enough to carry across the terrain. Additionally, Parkersburg and Fairmont are 70 miles apart, and UHF stations don't carry very well across long distances in any event.
Pre-mRNA-splicing regulator WTAP is a protein that in humans is encoded by the WTAP gene.
The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes. This gene encodes a WT1-associating protein, which is a ubiquitously expressed nuclear protein. Like WT1 protein, this protein is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors. Alternative splicing of this gene results in three transcript variants, two of which encode the same isoform.
WTAP (gene) has been shown to interact with WT1.